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Prostate Cancer Clinical Trials near St Louis, MO

56 studies for Prostate Cancer are recruiting at 139 sites within 50 miles of St Louis, Missouri, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Prostate Cancer trials in the US or all trials near St Louis.

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Recruiting now

Prostate Cancer studies enrolling near St Louis

Showing the 50 nearest of 56 studies.
  1. Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

    NCT04423211

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    13 sites within 50 mi
  2. Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

    NCT05334069

    • Observational
    • Ages 40 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    11 sites within 50 mi
  3. Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

    NCT05946213

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Missouri Baptist Medical Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    11 sites within 50 mi
  4. Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

    NCT06931340

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    11 sites within 50 mi
  5. Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

    NCT03866382

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    10 sites within 50 mi
  6. Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

    NCT03678025

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Missouri Baptist Medical Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    8 sites within 50 mi
  7. Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

    NCT06632977

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Siteman Cancer Center at Christian Hospital (St Louis, MO); Siteman Cancer Center-South County (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  8. Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment

    NCT06235697

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Siteman Cancer Center at Christian Hospital (St Louis, MO); Siteman Cancer Center-South County (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  9. Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

    NCT06592924

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Siteman Cancer Center at Christian Hospital (St Louis, MO); Siteman Cancer Center-South County (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  10. Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

    NCT06470243

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Missouri Baptist Medical Center (St Louis, MO); BJC Outpatient Center at Sunset Hills (Sunset Hills, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  11. Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

    NCT07200830

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Missouri Baptist Medical Center (St Louis, MO); Cancer Care Center of O'Fallon (O'Fallon, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  12. Vitamin D for Prostate Endocrine Therapy

    NCT05838716

    • Phase 3
    • Ages 50 years and older
    • Sex: Male

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Cancer Care Center of O'Fallon (O'Fallon, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  13. An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

    NCT05939414

    • Phase 3
    • Ages 18 to 100 years
    • Sex: Male

    Nearest sites: St Louis University (St Louis, MO); Wash U School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  14. CARE Tool Study Aim 3

    NCT07296887

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Washington University School of Medicine (St Louis, MO); Alton Memorial Hospital (Alton, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  15. Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

    NCT00969111

    • Interventional
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Mercy David C. Pratt Cancer Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate Brachytherapy

    NCT03424850

    • Phase 1/2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    NCT03452774

    • Observational
    • Ages Any age
    • Sex: All

    Nearest site: Massive Bio SYNERGY-AI site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy

    NCT03821246

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Alvin J. Siteman Cancer Center at Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

    NCT04221542

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

    NCT04354064

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Diffusion Basis Spectrum Imaging of the Prostate

    NCT04420702

    • Interventional
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. 64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)

    NCT04868604

    • Phase 1/2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Washington University School of Medicine at Barnes-Jewish Hospital (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

    NCT05011383

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: St. Louis VA Medical Center John Cochran Division, St. Louis, MO (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

    NCT05422911

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: VA St. Louis Health Care System (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

    NCT05519449

    • Phase 1
    • Ages 18 to 100 years
    • Sex: Male

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss

    NCT05593497

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: St. Louis VA Medical Center John Cochran Division, St. Louis, MO (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

    NCT05652686

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (Siteman Cancer Center) (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

    NCT05803941

    • Phase 4
    • Ages 18 to 100 years
    • Sex: Male

    Nearest site: Wash U School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

    NCT05804318

    • Interventional
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Washington University in St. Louis (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

    NCT05818683

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Washington University School Of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. FOG-001 in Locally Advanced or Metastatic Solid Tumors

    NCT05919264

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T

    NCT06134232

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Specialty Clinical Research of St. Louis (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

    NCT06136624

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine-Internal Medicine/Oncology ( Site 0062) (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

    NCT06172478

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University, School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. Study of AZD0754 in Participants With Metastatic Prostate Cancer

    NCT06267729

    • Phase 1/2
    • Ages 18 to 130 years
    • Sex: Male

    Nearest site: Research Site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

    NCT06440005

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

    NCT06465069

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine in St. Louis (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

    NCT06531499

    • Phase 1
    • Ages 18 to 100 years
    • Sex: Male

    Nearest site: Wash U School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

    NCT06533644

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Mercy Hospital (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

    NCT06545942

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Investigative Site #110 (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

    NCT06613100

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

    NCT06780670

    • Phase 2/3
    • Ages 18 to 100 years
    • Sex: Male

    Nearest site: WA Uni School Of Med (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

    NCT06785636

    • Phase 1/2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Siteman Cancer Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

    NCT06855277

    • Phase 3
    • Ages 18 to 100 years
    • Sex: Male

    Nearest site: Wash U School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. IDOV-Immune for Advanced Solid Tumors

    NCT06910657

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

    NCT06966024

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. The Vanguard Study: Testing a New Way to Screen for Cancer

    NCT06995898

    • Interventional
    • Ages 45 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. PSMA PET Combined With MRI for the Detection of PCa

    NCT07052214

    • Phase 3
    • Ages 18 years and older
    • Sex: Male
    • Accepts healthy volunteers

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System

    NCT07109427

    • Interventional
    • Ages 40 to 75 years
    • Sex: Male
    • Accepts healthy volunteers

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  50. A Study of LY4257496 in Participants With Cancer (OMNIRAY)

    NCT07114601

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Prostate Cancer clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.