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Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

NCT05422911

This study is recruiting at 12 US sites in 10 states, according to its ClinicalTrials.gov record last updated .

Summary

The investigators have used national VHA data to demonstrate real-world efficacy of abiraterone and enzalutamide in Veterans with mCRPC. In the real-world that is the VHA, the investigators have successfully estimated g values that accurately predict OS and the use of this metric in other settings should now be explored. In the egalitarian system that is the VHA the treatment of prostate cancer is excellent and uniform across the US. The choices made are clearly personalized, given not all men received all therapies and that younger Veterans were treated more aggressively.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Metastatic Cancer
  • Neoplasm, Prostate
  • Castrate-sensitive
  • Castrate-sensitive Prostate Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 years and older
Sex
Male
Healthy volunteers
Not accepted
Sponsor
Sun Pharmaceutical Industries Limited
Last updated on ClinicalTrials.gov
June 15, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • VA Greater Los Angeles Healthcare System · Los Angeles, CA

Florida · 1

  • James A. Haley Veterans Administration Hospital · Tampa, FL

Michigan · 1

  • VA Ann Arbor Healthcare System · Ann Arbor, MI

Missouri · 1

  • VA St. Louis Health Care System · St Louis, MO

New York · 3

  • VA New York Harbor Healthcare System · New York, NY
  • James J. Peters VA Medical Center · The Bronx, NY
  • VA Hudson Valley Health Care System · Wappingers Falls, NY

North Carolina · 1

  • W.G. Bill Hefner Medical Center · Salisbury, NC

Oregon · 1

  • VA Portland Health Care System · Portland, OR

Pennsylvania · 1

  • Corporal Michael J. Crescenz VA Medical Center · Philadelphia, PA

Texas · 1

  • Michael E. DeBakey VA Medical Center · Houston, TX

Washington · 1

  • VA Puget Sound Health Care System · Seattle, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.