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Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

NCT06545942

This study is recruiting at 8 US sites in 7 states, according to its ClinicalTrials.gov record last updated .

Summary

This Phase 1, multi-center, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and preliminary clinical activity of MOMA-313 administered orally as a single agent or combination therapy in patients with homologous recombinant deficient solid tumors.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Advanced Solid Tumor
  • Metastatic Solid Tumor
  • Prostate Cancer
  • Pancreas Cancer
  • Breast Cancer
  • Ovarian Cancer
  • Homologous Recombination Deficiency

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
MOMA Therapeutics
Last updated on ClinicalTrials.gov
July 23, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 1

  • Investigative Site #108 · Goodyear, AZ

California · 1

  • Investigative Site #101 · La Jolla, CA

Florida · 1

  • Investigative Site #104 · Lake Mary, FL

Missouri · 1

  • Investigative Site #110 · St Louis, MO

New York · 2

  • Investigative Site #103 · New York, NY
  • Investigative Site #106 · New York, NY

Pennsylvania · 1

  • Investigative Site #109 · Philadelphia, PA

Tennessee · 1

  • Investigative Site #102 · Nashville, TN

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.