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A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

NCT06440005

This study is recruiting at 7 US sites in 6 states, according to its ClinicalTrials.gov record last updated .

Summary

AGX101 is an antibody-drug conjugate (ADC) therapy for tumor-forming cancers. The purpose of this study is to learn about AGX101 effects and safety at various dose levels in an all-comers advanced solid cancer patient population. AGX101will be administered intravenously. Dosing of AGX101 will be repeated once every 3, 6 or 9 weeks. Participants may continue study treatment until disease progression, unacceptable toxicity, or consent withdrawal.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Cancer
  • Advanced Cancer
  • Locally Advanced Carcinoma
  • Metastatic Solid Tumor
  • Breast Cancer
  • Prostate Cancer
  • Colorectal Cancer
  • Pancreatic Cancer
  • Liver Cancer
  • Angiosarcoma
  • Solid Tumor

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Angiex, Inc.
Last updated on ClinicalTrials.gov
September 9, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • USC/Norris Comprehensive Cancer Center · Los Angeles, CA

Florida · 1

  • Florida Cancer Specialist · Sarasota, FL

Missouri · 1

  • Washington University School of Medicine · St Louis, MO

Tennessee · 1

  • Sarah Cannon Research Center · Nashville, TN

Texas · 2

  • UT MD Anderson · Houston, TX
  • NEXT Oncology · San Antonio, TX

Virginia · 1

  • NEXT Oncology · Fairfax, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.