A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC
NCT06785636
This study is recruiting at 19 US sites in 16 states, according to its ClinicalTrials.gov record last updated .
Summary
This is a dose-finding study to assess the safety and preliminary antitumor activity of Pocenbrodib alone or with darolutamide in patients with metastatic castration-resistant prostate cancer (mCRPC)
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- mCRPC (Metastatic Castration-resistant Prostate Cancer)
- Prostate Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 1/2
- Ages
- 18 years and older
- Sex
- Male
- Healthy volunteers
- Not accepted
- Sponsor
- Pathos AI, Inc.
- Last updated on ClinicalTrials.gov
- August 20, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 2
- MemorialCare Orange Coast Medical Center · Fountain Valley, CA
- Cancer and Blood Research Center · Los Alamitos, CA
Colorado · 1
- University of Colorado Health · Aurora, CO
Florida · 1
- Mount Sinai Medical Center · Miami, FL
Georgia · 1
- Emory University Hospital · Atlanta, GA
Illinois · 1
- University of Chicago · Chicago, IL
Indiana · 1
- Community Health Network · Indianapolis, IN
Louisiana · 1
- Ochsner · Jefferson, LA
Maryland · 1
- Johns Hopkins Hospital · Baltimore, MD
Michigan · 1
- Karmanos Cancer Institute · Detroit, MI
Missouri · 1
- Siteman Cancer Center · St Louis, MO
Nebraska · 1
- Nebraska Cancer Specialists · Omaha, NE
New York · 1
- Memorial Sloan-Kettering Cancer Center (Mskcc) · New York, NY
North Carolina · 1
- Duke University medical center · Durham, NC
Ohio · 2
- The Ohio State University · Columbus, OH
- Taylor Cancer Research Center · Maumee, OH
Texas · 2
- University of Texas Southwestern Medical Center · Dallas, TX
- Oncology Consultants, P.A · Houston, TX
Virginia · 1
- NEXT Oncology - Virginia · Fairfax, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.