FOG-001 in Locally Advanced or Metastatic Solid Tumors
NCT05919264
This study is recruiting at 30 US sites in 19 states, according to its ClinicalTrials.gov record last updated .
Summary
The goal of this clinical trial is to determine if FOG-001 is safe and effective in participants with locally advanced or metastatic solid tumors or in participants with familial adenomatous polyposis (FAP).
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Cancer
- Colorectal Cancer
- Solid Tumor
- Locally Advanced Solid Tumor
- Metastatic Cancer
- WNT Pathway
- HCC
- Desmoid
- Microsatellite Stable Colorectal Cancer
- Metastatic Castration-resistant Prostate Cancer
- Familial Adenomatous Polyposis (FAP)
- Endometrial Carcinoma
- Prostate Cancer
- Microsatellite Instability-High Colorectal Cancer
- Adamantinomatous Craniopharyngioma
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 1/2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Parabilis Medicines, Inc.
- Last updated on ClinicalTrials.gov
- October 7, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 3
- Mayo Clinic · Phoenix, AZ
- Honor Health · Scottsdale, AZ
- Arizona Cancer Center at University of Arizona · Tucson, AZ
California · 4
- University of California, Los Angeles (UCLA) · Los Angeles, CA
- Stanford Cancer Institute, Stanford University · Palo Alto, CA
- University of California San Francisco, Helen Diller Family Comprehensive Cancer Center · San Francisco, CA
- Sarcoma Oncology Center · Santa Monica, CA
Colorado · 1
- University of Colorado · Aurora, CO
Connecticut · 1
- Yale University School of Medicine · New Haven, CT
District of Columbia · 1
- Johns Hopkins University, Sibley Memorial Hospital · Washington D.C., DC
Florida · 1
- Mayo Clinic · Jacksonville, FL
Maryland · 1
- Johns Hopkins University, The Sidney Kimmel Comprehensive Cancer Center · Baltimore, MD
Massachusetts · 2
- Dana Farber Cancer Institute · Boston, MA
- Massachusetts General Hospital · Boston, MA
Minnesota · 2
- M Health Fairview University of Minnesota Medical Center · Minneapolis, MN
- Mayo Clinic · Rochester, MN
Missouri · 1
- Washington University School of Medicine · St Louis, MO
New York · 1
- Memorial Sloan Kettering Cancer Center · New York, NY
North Carolina · 1
- Duke University · Durham, NC
Ohio · 2
- Cleveland Clinic · Cleveland, OH
- University Hospitals Cleveland Medical Center, Seidman Cancer Center · Cleveland, OH
Oregon · 1
- Oregon Health and Science University · Portland, OR
Pennsylvania · 2
- University of Pennsylvania, Perelman School of Medicine · Philadelphia, PA
- University of Pittsburgh Medical Center, Hillman Cancer Center · Pittsburgh, PA
Tennessee · 2
- Sarah Cannon Research Institute · Nashville, TN
- Vanderbilt Ingram Cancer Center · Nashville, TN
Texas · 2
- The University of Texas MD Anderson Cancer Center · Houston, TX
- South Texas Accelerated Research Therapeutics, LLC · San Antonio, TX
Virginia · 1
- University of Virginia · Charlottesville, VA
Wisconsin · 1
- University of Wisconsin, Carbone Cancer Center · Madison, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.