A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
NCT07225946
This study is recruiting at 59 US sites in 29 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to find out whether treatment with pasritamig and docetaxel prolongs radiographic progression free survival (rPFS) (the length of time from start of treatment until disease worsens as determined by scans or death due to any cause) when compared to treatment with docetaxel in participants with metastatic castrate-resistant prostate cancer (mCRPC; a cancer of prostate, a male reproductive gland found below the bladder, that grows despite low levels of male hormones).
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Prostatic Neoplasms, Castration-Resistant
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Janssen Research & Development, LLC
- Last updated on ClinicalTrials.gov
- September 25, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 1
- Arizona Clinical Trials · Chandler, AZ
Arkansas · 1
- Arkansas Urology · Little Rock, AR
California · 9
- MemorialCare Orange Coast Medical Center · Fountain Valley, CA
- University Of California San Diego · La Jolla, CA
- Cancer and Blood Specialty Clinic · Los Alamitos, CA
- Ronald Reagan UCLA Medical Center · Los Angeles, CA
- USC Norris Comprehensive Cancer Center · Los Angeles, CA
- Valkyrie Clinical Trials · Los Angeles, CA
- Kaiser Permanente Southern California · Riverside, CA
- Sharp Center for Research · San Diego, CA
- Providence Saint John s Health Center · Santa Monica, CA
Colorado · 5
- Rocky Mountain Cancer Centers · Aurora, CO
- AdventHealth Porter Oncology Research · Denver, CO
- Vail Health Shaw Cancer Center · Edwards, CO
- Grand Valley Oncology · Grand Junction, CO
- Colorado Clinical Research · Lakewood, CO
Florida · 2
- AdventHealth Orlando · Orlando, FL
- Florida Cancer Specialists · Sarasota, FL
Georgia · 1
- Winship Cancer Institute Emory University · Atlanta, GA
Illinois · 1
- Duly Health and Care · Lisle, IL
Kansas · 1
- Cancer Center of Kansas Heritage Plaza Medical Building · Wichita, KS
Kentucky · 2
- St Elizabeth Healthcare · Edgewood, KY
- Norton Cancer Institute · Louisville, KY
Louisiana · 1
- East Jefferson General Hospital · Metairie, LA
Maryland · 4
- Johns Hopkins Hospital · Baltimore, MD
- Johns Hopkins Medical Institutions · Baltimore, MD
- University of Maryland · Baltimore, MD
- Chesapeake Urology Research Associates · Towson, MD
Massachusetts · 1
- Massachusetts General · Boston, MA
Michigan · 1
- Profound Research LLC at Cancer and Leukemia Center · Sterling Heights, MI
Minnesota · 2
- HealthPartners Frauenshuh Cancer Center CRC West · Saint Louis Park, MN
- HealthPartners Cancer Center at Regions Hospital CRC East · Saint Paul, MN
Mississippi · 1
- University of Mississippi Medical Center · Jackson, MS
Missouri · 1
- Washington University · St Louis, MO
Nebraska · 1
- NHO Revive Research Institute, LLC · Lincoln, NE
New Jersey · 2
- Astera Cancer Care · East Brunswick, NJ
- Rutgers Cancer Institute of New Jersey · New Brunswick, NJ
New York · 3
- Laura & Isaac Perlmutter Cancer Center at NYU Langone Hospital - Long Island · Mineola, NY
- NYU Langone Health Laura and Isaac Perlmutter Cancer Center · New York, NY
- Montefiore Medical Center · The Bronx, NY
North Carolina · 1
- Duke University Medical Center · Durham, NC
Ohio · 1
- University of Cincinnati · Cincinnati, OH
Oregon · 1
- Oregon Urology Institute · Springfield, OR
Pennsylvania · 4
- Lehigh Valley Hospital · Allentown, PA
- MidLantic Urology · Bala-Cynwyd, PA
- Penn State Milton S. Hershey Medical Center · Hershey, PA
- University Of Pittsburgh Medical Center UPMC Hillman Cancer Center · Pittsburgh, PA
South Carolina · 1
- Carolina Urologic Research Center · Myrtle Beach, SC
South Dakota · 2
- Avera Medical Group · Sioux Falls, SD
- Prairie Lakes Health Care System · Watertown, SD
Tennessee · 1
- Tennessee Cancer Specialists · Knoxville, TN
Texas · 5
- Texas Oncology · Austin, TX
- UT Southwestern Medical Center · Dallas, TX
- Houston Metro Urology · Houston, TX
- Texas Oncology 1 · Sugar Land, TX
- Renovatio Clinical · The Woodlands, TX
Virginia · 1
- Virginia Cancer Specialists · Fairfax, VA
Washington · 2
- Fred Hutch Cancer Center Sloan Clinic 2 · Seattle, WA
- Fred Hutchinson Cancer Research Center · Seattle, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.