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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

NCT03452774

This study is recruiting at 67 US sites in 40 states, according to its ClinicalTrials.gov record last updated .

Summary

International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinical impact on pts with advanced cancer to facilitate clinical trial enrollment (CTE), as well as the financial impact, and potential outcomes of the intervention.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Cancer, Metastatic
  • Cancer
  • Cancer of Pancreas
  • Cancer of Liver
  • Cancer of Stomach
  • Cancer Liver
  • Cancer of Rectum
  • Cancer of Kidney
  • Cancer of Esophagus
  • Cancer of Cervix
  • Cancer of Colon
  • Cancer of Larynx
  • Cancer, Lung
  • Cancer, Breast
  • Cancer, Advanced
  • Cancer Prostate
  • Cancer of Neck
  • Cancer of Skin
  • Neuroendocrine Tumors
  • Carcinoma
  • Mismatch Repair Deficiency
  • BRCA Gene Rearrangement
  • Non Hodgkin Lymphoma
  • Leukemia
  • Non Small Cell Lung Cancer
  • Cholangiocarcinoma
  • Glioblastoma
  • Central Nervous System Tumor
  • Melanoma
  • Urothelial Carcinoma
  • Bladder Cancer
  • Ovarian Cancer
  • Endometrial Cancer
  • Testicular Cancer
  • Breast Cancer
  • COVID
  • Myelofibrosis
  • Myeloproliferative Neoplasm
  • Myeloproliferative Disorders
  • Follicular Lymphoma
  • Mantle Cell Lymphoma
  • Marginal Zone Lymphoma
  • Myelodysplastic Syndromes

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
Any age
Sex
All
Healthy volunteers
Not accepted
Sponsor
Massive Bio, Inc.
Last updated on ClinicalTrials.gov
October 28, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Alabama · 2

  • Massive Bio SYNERGY-AI site · Birmingham, AL
  • Massive Bio SYNERGY-AI site · Mobile, AL

Arizona · 1

  • Massive Bio SYNERGY-AI site · Scottsdale, AZ

Arkansas · 1

  • Massive Bio SYNERGY-AI site · Little Rock, AR

California · 6

  • Massive Bio SYNERGY-AI site · Duarte, CA
  • Massive Bio SYNERGY-AI site · Irvine, CA
  • Massive Bio SYNERGY-AI site · La Jolla, CA
  • Massive Bio SYNERGY-AI site · Orange, CA
  • Massive Bio SYNERGY-AI site · San Francisco, CA
  • Massive Bio SYNERGY-AI site · Stanford, CA

Colorado · 3

  • Massive Bio SYNERGY-AI site · Aurora, CO
  • Massive Bio SYNERGY-AI site · Denver, CO
  • Massive Bio SYNERGY-AI site · Littleton, CO

Connecticut · 2

  • Massive Bio SYNERGY-AI site · Hartford, CT
  • Massive Bio SYNERGY-AI site · Norwalk, CT

Delaware · 1

  • Massive Bio SYNERGY-AI site · Newark, DE

Florida · 3

  • Massive Bio SYNERGY-AI site · Jacksonville, FL
  • Massive Bio SYNERGY-AI site · Miami, FL
  • Massive Bio SYNERGY-AI site · Tampa, FL

Georgia · 2

  • Massive Bio SYNERGY-AI site · Atlanta, GA
  • Massive Bio SYNERGY-AI site · Savannah, GA

Idaho · 1

  • Massive Bio SYNERGY-AI site · Boise, ID

Illinois · 1

  • Massive Bio SYNERGY-AI site · Chicago, IL

Iowa · 1

  • Massive Bio SYNERGY-AI site · Iowa City, IA

Louisiana · 1

  • Massive Bio SYNERGY-AI site · New Orleans, LA

Maine · 1

  • Massive Bio SYNERGY-AI site · Scarborough, ME

Maryland · 4

  • Massive Bio SYNERGY-AI site · Baltimore, MD
  • Massive Bio SYNERGY-AI site · Bethesda, MD
  • Massive Bio SYNERGY-AI site · Silver Spring, MD
  • Massive Bio SYNERGY-AI site · Towson, MD

Massachusetts · 1

  • Massive Bio SYNERGY-AI site · Worcester, MA

Michigan · 2

  • Massive Bio SYNERGY-AI site · Ann Arbor, MI
  • Massive Bio SYNERGY-AI site · Lansing, MI

Minnesota · 1

  • Massive Bio SYNERGY-AI site · Duluth, MN

Mississippi · 1

  • Massive Bio SYNERGY-AI site · Hattiesburg, MS

Missouri · 2

  • Massive Bio SYNERGY-AI site · Kansas City, MO
  • Massive Bio SYNERGY-AI site · St Louis, MO

Montana · 1

  • Massive Bio SYNERGY-AI site · Billings, MT

Nebraska · 1

  • Massive Bio SYNERGY-AI site · Omaha, NE

New Jersey · 1

  • Massive Bio SYNERGY-AI site · New Brunswick, NJ

New Mexico · 1

  • Massive Bio SYNERGY-AI site · Albuquerque, NM

New York · 5

  • Massive Bio SYNERGY-AI site · Buffalo, NY
  • Massive Bio SYNERGY-AI site · Hempstead, NY
  • Massive Bio SYNERGY-AI site · Manhasset, NY
  • Massive Bio SYNERGY-AI site · New York, NY
  • Massive Bio SYNERGY-AI site · Staten Island, NY

North Carolina · 2

  • Massive Bio SYNERGY-AI site · Chapel Hill, NC
  • Massive Bio SYNERGY-AI site · Winston-Salem, NC

North Dakota · 1

  • Massive Bio SYNERGY-AI site · Fargo, ND

Ohio · 3

  • Massive Bio SYNERGY-AI site · Cincinnati, OH
  • Massive Bio SYNERGY-AI site · Columbus, OH
  • Massive Bio SYNERGY-AI site · Mayfield Heights, OH

Oklahoma · 1

  • Massive Bio SYNERGY-AI site · Tulsa, OK

Oregon · 1

  • Massive Bio SYNERGY-AI site · Portland, OR

Pennsylvania · 1

  • Massive Bio SYNERGY-AI site · Philadelphia, PA

Rhode Island · 1

  • Massive Bio SYNERGY-AI site · Providence, RI

South Carolina · 1

  • Massive Bio SYNERGY-AI site · Greenville, SC

Tennessee · 2

  • Massive Bio SYNERGY-AI site · Memphis, TN
  • Massive Bio SYNERGY-AI site · Nashville, TN

Texas · 3

  • Massive Bio SYNERGY-AI site · Dallas, TX
  • Massive Bio SYNERGY-AI site · Houston, TX
  • Massive Bio SYNERGY-AI site · Temple, TX

Utah · 1

  • Massive Bio SYNERGY-AI site · Salt Lake City, UT

Virginia · 1

  • Massive Bio SYNERGY-AI site · Charlottesville, VA

Washington · 1

  • Massive Bio SYNERGY-AI site · Seattle, WA

West Virginia · 1

  • Massive Bio SYNERGY-AI site · Morgantown, WV

Wisconsin · 1

  • Massive Bio SYNERGY-AI site · Milwaukee, WI

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.