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Prostate Cancer Clinical Trials near Philadelphia, PA

58 studies for Prostate Cancer are recruiting at 107 sites within 50 miles of Philadelphia, Pennsylvania, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Prostate Cancer trials in the US or all trials near Philadelphia.

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Prostate Cancer studies enrolling near Philadelphia

Showing the 50 nearest of 58 studies.
  1. Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

    NCT06592924

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Philadelphia Veterans Administration Medical Center (Philadelphia, PA); Christiana Care Health System-Concord Health Center (Chadds Ford, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  2. Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

    NCT06931340

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Jefferson Torresdale Hospital (Philadelphia, PA); Thomas Jefferson University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  3. Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

    NCT04423211

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Penn Presbyterian Medical Center (Philadelphia, PA); Thomas Jefferson University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  4. A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

    NCT05125016

    • Phase 1/2
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Fox Chase Cancer Center (Philadelphia, PA); Penn Medicine University of Pennsylvania Health System (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  5. International Registry for Men With Advanced Prostate Cancer (IRONMAN)

    NCT03151629

    • Observational
    • Ages 21 years and older
    • Sex: Male

    Nearest sites: Fox Chase Cancer Center - Temple Health (Philadelphia, PA); Reading Health System (West Reading, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  6. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    NCT03452774

    • Observational
    • Ages Any age
    • Sex: All

    Nearest sites: Massive Bio SYNERGY-AI site (Philadelphia, PA); Massive Bio SYNERGY-AI site (Newark, DE)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  7. The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

    NCT04585750

    • Phase 1/2
    • Ages 12 years and older
    • Sex: All

    Nearest sites: Abramson Cancer Center of the University of Pennsylvania (Philadelphia, PA); Medical Oncology Hematology Consultants (Newark, DE)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  8. A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

    NCT06136650

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Fox Chase Cancer Center ( Site 0076) (Philadelphia, PA); MidLantic urology ( Site 0022) (Bala-Cynwyd, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  9. A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

    NCT06778863

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Fox Chase Cancer Center (Philadelphia, PA); Thomas Jefferson University, Sidney Kimmel Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  10. A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

    NCT06925737

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Abramson Cancer Center - Penn Medicine ( Site 0079) (Philadelphia, PA); Perelman Center for Advanced Medicine ( Site 0067) (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  11. A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

    NCT07164443

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Penn Medicine Abramson Cancer Center (Philadelphia, PA); MidLantic Urology (Bala-Cynwyd, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  12. A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors

    NCT03972657

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Thomas Jefferson University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

    NCT04038502

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Philadelphia MultiService Center, Philadelphia, PA (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

    NCT04104776

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Abramson Cancer Center of the University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

    NCT04221542

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Thomas Jefferson University (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

    NCT04373564

    • Phase 4
    • Ages 18 to 64 years
    • Sex: All

    Nearest site: Albert Einstein Healthcare Network (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

    NCT04472338

    • Observational
    • Ages 40 years and older
    • Sex: Male
    • Accepts healthy volunteers

    Nearest site: University of Pennsylvania/Abramson Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

    NCT04787744

    • Phase 2/3
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

    NCT05176483

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Exelixis Clinical Site #98 (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. TERPS Trial for de Novo Oligometastic Prostate Cancer

    NCT05223803

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Sidney Kimmel Cancer Center at Jefferson Health (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. FTT PET/CT in Metastatic Prostate Cancer

    NCT05242744

    • Observational
    • Ages 18 years and older
    • Sex: Male

    Nearest site: University of Pennsylvania Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

    NCT05422911

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Corporal Michael J. Crescenz VA Medical Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation

    NCT05487846

    • Interventional
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

    NCT05519449

    • Phase 1
    • Ages 18 to 100 years
    • Sex: Male

    Nearest site: Thomas Jefferson University Honickman Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network

    NCT05627219

    • Observational
    • Ages 18 years and older
    • Sex: Male
    • Accepts healthy volunteers

    Nearest site: Sidney Kimmel Cancer Center at Thomas Jefferson University (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

    NCT05818683

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Sidney Kimmel Cancer Center - Jefferson Health (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. FOG-001 in Locally Advanced or Metastatic Solid Tumors

    NCT05919264

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania, Perelman School of Medicine (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

    NCT06095089

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Sidney Kimmel Cancer Center - Jefferson Health (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Study of AZD0754 in Participants With Metastatic Prostate Cancer

    NCT06267729

    • Phase 1/2
    • Ages 18 to 130 years
    • Sex: Male

    Nearest site: Research Site (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

    NCT06395519

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Thomas Jefferson University, Sidney Kimmel Comprehensive Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

    NCT06545942

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Investigative Site #109 (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Hypofractionated WPPT With HDR Boost

    NCT06591819

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

    NCT06613100

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Thomas Jefferson University (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. Prostate Tissue BioBank

    NCT06659614

    • Observational
    • Ages 18 years and older
    • Sex: Male

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

    NCT06780670

    • Phase 2/3
    • Ages 18 to 100 years
    • Sex: Male

    Nearest site: Fox Chase Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide

    NCT06844383

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Abramson Cancer Center of the University of Pennsylvania, Hospital of the University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

    NCT06966024

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Fox Chase Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. PSMA PET Combined With MRI for the Detection of PCa

    NCT07052214

    • Phase 3
    • Ages 18 years and older
    • Sex: Male
    • Accepts healthy volunteers

    Nearest site: MidLantic Urology (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. A Study of Tarlatamab for People With Prostate Cancer

    NCT07111507

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Thomas Jefferson University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. DESTINY-PANTUMOUR04

    NCT07124000

    • Observational
    • Ages 18 to 130 years
    • Sex: All

    Nearest site: Research Site (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

    NCT07140900

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Thomas Jefferson University (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. Adaptive Radiation Therapy for Men With Intermediate- or High-Risk Prostate Cancer

    NCT07219303

    • Interventional
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Fox Chase Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. First-Time-in-Human Study of GSK5471713 in Adults With mCRPC

    NCT07332455

    • Phase 1/2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: GSK Investigational Site (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

    NCT07493512

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Thomas Jefferson University (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

    NCT07225946

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: MidLantic Urology (Bala-Cynwyd, PA); Lehigh Valley Hospital (Allentown, PA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  46. A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

    NCT04729114

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: MidLantic Urology (Bala-Cynwyd, PA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T

    NCT06134232

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: MidLantic Urology (Bala-Cynwyd, PA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. Sacral Neuromodulation for Male Overactive Bladder (MOAB)

    NCT06511141

    • Interventional
    • Ages 18 years and older
    • Sex: Male

    Nearest site: MidLantic Urology (Bala-Cynwyd, PA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

    NCT07028853

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest site: MidLantic urology (Bala-Cynwyd, PA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  50. Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

    NCT05334069

    • Observational
    • Ages 40 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Inspira Medical Center Mullica Hill (Mullica Hill, NJ); Reading Hospital McGlinn Cancer Institute at Phoenixville (Phoenixville, PA)

    Distance to nearest recruiting site
    ~15 mi (city-level)
    Recruiting sites
    8 sites within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Prostate Cancer clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.