Clinical Trials Recruiting near Philadelphia, PA

1,863 clinical trials have a recruiting site within 25 miles of Philadelphia, Pennsylvania, according to ClinicalTrials.gov data processed October 15, 2026. The closest recruiting site is within 1 mile of the city center.

Distances are measured from the city center to each site's city, so they are approximate.

Recruiting now

Studies enrolling near Philadelphia

Showing 30 studies, nearest first.

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
NCT03072927
- Observational
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
54 sites within 25 mi
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
NCT05879926
- Phase 3
- Ages 18 to 60 years
- Sex: Female
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
19 sites within 25 mi
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
NCT05929768
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
12 sites within 25 mi
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
NCT03851445
- Phase 2/3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
11 sites within 25 mi
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
NCT05624996
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
11 sites within 25 mi
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
NCT04251052
- Interventional
- Ages 35 to 50 years
- Sex: Female
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
10 sites within 25 mi
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
NCT06580314
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
10 sites within 25 mi
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
NCT05174169
- Phase 2/3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
9 sites within 25 mi
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers
NCT04239573
- Observational
- Ages 50 to 75 years
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
8 sites within 25 mi
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
NCT04267848
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
8 sites within 25 mi
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
NCT04852887
- Phase 3
- Ages 50 to 70 years
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
8 sites within 25 mi
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
NCT05564377
- Phase 2
- Ages Any age
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
8 sites within 25 mi
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
NCT05812807
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
8 sites within 25 mi
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
NCT06876714
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
8 sites within 25 mi
Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention
NCT05748730
- Interventional
- Ages 12 to 18 years
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
7 sites within 25 mi
Assessment of CCM in HF With Higher Ejection Fraction
NCT05064709
- Interventional
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
6 sites within 25 mi
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
NCT05677490
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
6 sites within 25 mi
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
NCT06958328
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
6 sites within 25 mi
Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma
NCT07068074
- Phase 3
- Ages 75 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
6 sites within 25 mi
Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
NCT04031677
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
NCT04858334
- Phase 2
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi
Time Restricted Eating for the Improvement of Outcomes in Patients With Stage I-III Breast Cancer Receiving Chemotherapy Before Surgery
NCT05327608
- Interventional
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
NCT05640999
- Phase 2
- Ages 18 years and older
- Sex: Female
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
NCT05675410
- Phase 3
- Ages 5 to 60 years
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
NCT05987241
- Phase 2/3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
NCT06096844
- Phase 3
- Ages 70 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
NCT06203600
- Phase 2/3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
NCT06492616
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
NCT06498635
- Phase 3
- Ages 18 years and older
- Sex: All
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
NCT06513962
- Phase 3
- Ages Up to 39 years
- Sex: Female
Distance to nearest recruiting site
<1 mi (city-level)
Recruiting sites
5 sites within 25 mi

By condition

Clinical trials in Philadelphia by condition

Source: ClinicalTrials.gov, data processed October 15, 2026. Recruiting US sites filtered by distance and site status; summaries shortened.