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Heart Failure Clinical Trials near Philadelphia, PA

35 studies for Heart Failure are recruiting at 58 sites within 50 miles of Philadelphia, Pennsylvania, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Heart Failure trials in the US or all trials near Philadelphia.

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Heart Failure studies enrolling near Philadelphia

Showing 35 studies, nearest first.
  1. Assessment of CCM in HF With Higher Ejection Fraction

    NCT05064709

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Hospital of the University of Pennsylvania (Philadelphia, PA); Penn Presbyterian Medical Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  2. Left vs Left Randomized Clinical Trial

    NCT05650658

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Thomas Jefferson University Hospital (Philadelphia, PA); University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  3. Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

    NCT00271180

    • Observational
    • Ages Any age
    • Sex: All

    Nearest sites: (Philadelphia, PA); (Marlton, NJ)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  4. Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

    NCT06677060

    • Phase 3
    • Ages 40 years and older
    • Sex: All

    Nearest sites: Research Site (Philadelphia, PA); Research Site (Horsham, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  5. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

    NCT03142152

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: University of Pennsylvania (Philadelphia, PA); Lankenau Institute of Medical Research (Wynnewood, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  6. Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

    NCT05677100

    • Interventional
    • Ages 21 years and older
    • Sex: All

    Nearest sites: Penn Presbyterian Medical Center (Philadelphia, PA); Jefferson Abington Hospital (Abington, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  7. A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

    NCT06008197

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Philadelphia, PA Investigative Site 10068 (Philadelphia, PA); Camden, NJ Investigative Site 10033 (Camden, NJ)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  8. Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

    NCT06307652

    • Phase 3
    • Ages 18 to 130 years
    • Sex: All

    Nearest sites: Research Site (Philadelphia, PA); Research Site (Abington, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  9. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

    NCT06526195

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: University of Pennsylvania (Philadelphia, PA); Abington Memorial Hospital (Abington, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  10. Matching Perfusion and Metabolic Activity in HFpEF

    NCT04913805

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial

    NCT05138575

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania Health System (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. His-Bundle Corrective Pacing in Heart Failure

    NCT05265520

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

    NCT05714085

    • Phase 2/3
    • Ages 29 days to 17 years
    • Sex: All

    Nearest site: Children's Hospital of Philadelphia (CHOP) ( Site 0004) (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets

    NCT05873634

    • Observational
    • Ages 30 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

    NCT06024746

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Philadelphia, PA Investigative Site CON-10068 (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

    NCT06291922

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

    NCT06310031

    • Interventional
    • Ages 18 to 100 years
    • Sex: All

    Nearest site: Thomas Jefferson University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

    NCT06517186

    • Observational
    • Ages 30 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure

    NCT06552637

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction

    NCT06670001

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: The University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

    NCT06736574

    • Phase 3
    • Ages 18 to 85 years
    • Sex: All

    Nearest site: Hospital of the University of Pennsylvania (University of Pennsylvania School of Medicine) (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

    NCT06898515

    • Interventional
    • Ages 22 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. Cholate Clearance in Fontan and Heart Failure

    NCT07009132

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Hospital of the University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

    NCT07069738

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Penn Presbyterian Medical Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. NORM-HF Pivotal Study

    NCT07574593

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. The HEARTFELT Study

    NCT06222099

    • Interventional
    • Ages 22 years and older
    • Sex: All

    Nearest site: Connect America (Bala-Cynwyd, PA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. ELEVATE-HFpEF Clinical Study

    NCT06678841

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest site: Lankenau Institute for Medical Research (Wynnewood, PA)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

    NCT07567001

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Heart House - Sewell (Sewell, NJ)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

    NCT07037459

    • Phase 3
    • Ages 18 to 99 years
    • Sex: All

    Nearest sites: Virtua Health Incorporated (Marlton, NJ); Abington Medical Specialists (Horsham, PA)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  30. Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure

    NCT07209098

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Impulse Dynamics (Marlton, NJ)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Tezspire Cardiac Events PASS

    NCT06951867

    • Observational
    • Ages 12 to 130 years
    • Sex: All

    Nearest site: Healthcare Integrated Research Database (HIRD) (Wilmington, DE)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

    NCT06935370

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Cardiology Consultants of Philadelphia (Yardley, PA)

    Distance to nearest recruiting site
    ~26 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Alleviant ALLAY-HFrEF Study

    NCT06812533

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Deborah Heart & Lung Center (Browns Mills, NJ)

    Distance to nearest recruiting site
    ~31 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

    NCT06424288

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Garden State Heart Care, PC (Manalapan, NJ)

    Distance to nearest recruiting site
    ~46 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

    NCT05489705

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: St. Luke's University Health Network (Bethlehem, PA)

    Distance to nearest recruiting site
    ~48 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Heart Failure clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.