The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
NCT03142152
This study is recruiting at 51 US sites in 22 states, according to its ClinicalTrials.gov record last updated .
Summary
The objective of this prospective, randomized, double- blinded (patient and assessors), sham-controlled clinical trial is to assess the safety and efficacy of the CMCS in treating heart failure with functional regurgitation (FMR).
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Functional Mitral Regurgitation
- Heart Failure
- Mitral Valve Insufficiency
- Heart Diseases
- Cardiovascular Diseases
- Heart Valve Diseases
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Cardiac Dimensions, Inc.
- Last updated on ClinicalTrials.gov
- April 13, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 4
- Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers · Gilbert, AZ
- Banner Health - Phoenix · Phoenix, AZ
- Banner University Tuscon · Tucson, AZ
- Tucson Medical Center Health · Tucson, AZ
California · 5
- Keck School of Medicine of USC · Los Angeles, CA
- UCLA Medical Center · Los Angeles, CA
- Stanford University · Redwood City, CA
- Scripps Health · San Diego, CA
- University of California- San Francisco · San Francisco, CA
Colorado · 1
- South Denver Cardiology · Littleton, CO
Florida · 3
- Advent Health Hospital · Orlando, FL
- Palm Beach Gardens Medical · Palm Beach, FL
- Tampa General Hospital · Tampa, FL
Illinois · 2
- Advocate Good Samaritan · Downers Grove, IL
- Midwest Cardiovascular Institute (MCI) · Naperville, IL
Indiana · 1
- Community Health Network · Indianapolis, IN
Louisiana · 2
- Cardiovascular Institute South · Houma, LA
- Ochsner Health System · New Orleans, LA
Maryland · 1
- Johns Hopkins · Baltimore, MD
Massachusetts · 3
- Beth Israel Deaconess · Boston, MA
- Massachusetts General Hospital · Boston, MA
- St Elizabeth's Medical Center · Boston, MA
Minnesota · 1
- CentraCare Heart and Vascular · Saint Cloud, MN
Missouri · 1
- St. Louis Heart and Vascular · St Louis, MO
New Jersey · 3
- Deborah Heart & Lung · Browns Mills, NJ
- Hackensack University Medical Center · Edison, NJ
- St Michael/Prime Healthcare Services · Newark, NJ
New York · 4
- University at Buffalo · Buffalo, NY
- Northwell Staten Island · New York, NY
- Vassar Brothers- Hudson Valley Cardiovascular Practice · Poughkeepsie, NY
- Rochester Regional Hospital · Rochester, NY
Ohio · 4
- Lindner Research Center at the Christ Hospital · Cincinnati, OH
- Cleveland Clinic · Cleveland, OH
- The Ohio State University · Columbus, OH
- Kettering Health Research Institute · Dayton, OH
Oklahoma · 2
- Oklahoma Heart Institute Hospital · Tulsa, OK
- Saint Francis Hospital, · Tulsa, OK
Oregon · 2
- Oregon Health & Science University (OHSU) · Portland, OR
- Providence Heart Institute · Portland, OR
Pennsylvania · 5
- Penn Medicine Lancaster General Health · Lancaster, PA
- UPMC Pinnacle Hospitals · Mechanicsburg, PA
- University of Pennsylvania · Philadelphia, PA
- Allegheny Health Network · Pittsburgh, PA
- Lankenau Institute of Medical Research · Wynnewood, PA
South Dakota · 1
- North Central Heart-Avera · Sioux Falls, SD
Tennessee · 1
- Centennial Medical Center · Nashville, TN
Texas · 1
- Houston Healthcare Medical Center · Houston, TX
Virginia · 3
- Henrico Doctors Hospital · Henrico, VA
- HCA Chippenham Medical Center · Richmond, VA
- Carilion Hospital · Roanoke, VA
Wisconsin · 1
- Advocate Aurora Research Institute · Milwaukee, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.