Skip to content
Trial Eligibility
Menu

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

NCT05489705

This study is recruiting at 48 US sites in 27 states, according to its ClinicalTrials.gov record last updated .

Summary

This registry evaluates patient characteristics, real-world treatment patterns, and short- and long-term outcomes in a population of patients in the United States and Europe with symptomatic obstructive hypertrophic cardiomyopathy (HCM) who are receiving mavacamten, receiving other treatment for obstructive HCM, or not receiving treatment for obstructive HCM due to intolerance or failure of prior treatment. United States Sub-Study: The purpose of this study is to evaluate the safety of mavacamten in patients with symptomatic obstructive HCM in the real-world setting.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Obstructive Hypertrophic Cardiomyopathy

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Bristol-Myers Squibb
Last updated on ClinicalTrials.gov
August 19, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Alaska · 1

  • Alaska Heart Institute · Anchorage, AK

Arizona · 1

  • Pima Heart and Vascular · Tucson, AZ

Arkansas · 1

  • UAMS · Little Rock, AR

California · 3

  • Keck School of Medicine of USC-Usc · Los Angeles, CA
  • Stanford Health Care Hospital & Clinics · Palo Alto, CA
  • University Of California San Francisco Medical Center · San Francisco, CA

Colorado · 1

  • UC Denver, AMC · Aurora, CO

District of Columbia · 1

  • MedStar Washington Hospital Center · Washington D.C., DC

Illinois · 1

  • University of Chicago Dept of Medicine · Chicago, IL

Indiana · 2

  • Franciscan Physician Network-Indiana Heart Physicians · Indianapolis, IN
  • Indiana. University · Indianapolis, IN

Maryland · 1

  • MedStar Health Research Institute · Baltimore, MD

Massachusetts · 2

  • Harvard (Massachusetts General Hospital) · Boston, MA
  • Harvard Medical School - Brigham and Women's Hospital (BWH) · Boston, MA

Michigan · 2

  • Spectrum Health Medical Group · Grand Rapids, MI
  • Henry Ford Health System · West Bloomfield, MI

Minnesota · 1

  • Minneapolis Heart Institute Foundation · Minneapolis, MN

Mississippi · 1

  • Cardiology Associates Research, Llc · Tupelo, MS

Missouri · 2

  • St. Luke's Mid-America Heart Institute · Kansas City, MO
  • Washington University · St Louis, MO

Nebraska · 1

  • CHI Health Reseach Center · Omaha, NE

New Jersey · 1

  • Hackensack University Medical Center · Hackensack, NJ

New York · 4

  • Bassett Medical Center · Cooperstown, NY
  • Mount Sinai Hospital · New York, NY
  • Saint Francis Hospital · Roslyn, NY
  • WMCHealth Advanced Physician Services · Valhalla, NY

North Carolina · 2

  • Focus Clinical Research · Charlotte, NC
  • Duke University Health System · Durham, NC

Ohio · 2

  • Christ Hospital Health Network · Cincinnati, OH
  • University Hospitals Cleveland Medical Center · Cleveland, OH

Pennsylvania · 3

  • St. Luke's University Health Network · Bethlehem, PA
  • University Of Pittsburgh · Pittsburgh, PA
  • Geisinger Health System · Wilkes-Barre, PA

South Carolina · 1

  • Prisma Health - Upstate · Greenville, SC

Tennessee · 2

  • Saint Thomas Health · Nashville, TN
  • Tristar Centennial Medical Ctr · Nashville, TN

Texas · 6

  • Baylor Scott & White Research Institute · Dallas, TX
  • North Texas Cardiology Center · Dallas, TX
  • BI Research Center · Houston, TX
  • The Methodist Hospital, Methodist Cancer Cencer · Houston, TX
  • Baylor Scott & White The Heart Hospital Plano · Plano, TX
  • Baylor Scott & White Medical Centre - Temple · Temple, TX

Virginia · 3

  • The Rector and Visitors of the Univ of Virginia · Charlottesville, VA
  • VCU Medical Center · Richmond, VA
  • Carilion Clinic; Virginia Tech-Carilion School of Medicine · Roanoke, VA

Washington · 1

  • Virginia Mason Medical Center · Seattle, WA

West Virginia · 1

  • WVU Hospitals · Morgantown, WV

Wisconsin · 1

  • Medical College of Wisconsin, Inc (PI Address) · Milwaukee, WI

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.