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His-Bundle Corrective Pacing in Heart Failure

NCT05265520

This study is recruiting at 14 US sites in 10 states, according to its ClinicalTrials.gov record last updated .

Summary

The investigators aim to prospectively evaluate the efficacy and mechanism of benefit of His-bundle pacing enhanced cardiac resynchronization therapy (His-CRT) vs. cardiac resynchronization therapy (BIV-CRT) in patients with heart failure and right bundle branch block (RBBB).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Right Bundle-Branch Block
  • Heart Failure
  • His-bundle Pacing
  • Cardiac Resynchronization Therapy

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
University of Rochester
Last updated on ClinicalTrials.gov
February 9, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 1

  • University of Arizona · Phoenix, AZ

California · 1

  • Cedars-Sinai Medical Center · Los Angeles, CA

Florida · 1

  • University of South Florida · Tampa, FL

Illinois · 3

  • Northwestern Memorial Hospital · Chicago, IL
  • Rush University Medical Center · Chicago, IL
  • University of Chicago · Chicago, IL

New Jersey · 1

  • Valley Health System · Ridgewood, NJ

New York · 2

  • Mount Sinai Hospital · New York, NY
  • Weill Cornell Medical College · New York, NY

North Carolina · 1

  • Mission Health · Asheville, NC

Pennsylvania · 2

  • University of Pennsylvania · Philadelphia, PA
  • Geisinger Wyoming Valley · Wilkes-Barre, PA

Vermont · 1

  • University of Vermont · Burlington, VT

Virginia · 1

  • Virginia Commonwealth University · Richmond, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.