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Lung Cancer Clinical Trials near Philadelphia, PA

107 studies for Lung Cancer are recruiting at 237 sites within 50 miles of Philadelphia, Pennsylvania, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Lung Cancer trials in the US or all trials near Philadelphia.

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Recruiting now

Lung Cancer studies enrolling near Philadelphia

Showing the 50 nearest of 107 studies.
  1. Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

    NCT03851445

    • Phase 2/3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Fox Chase Cancer Center (Philadelphia, PA); Temple University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    17 sites within 50 mi
  2. Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

    NCT05624996

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Fox Chase Cancer Center (Philadelphia, PA); Temple University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    15 sites within 50 mi
  3. Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

    NCT04267848

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Fox Chase Cancer Center (Philadelphia, PA); Temple University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    13 sites within 50 mi
  4. Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

    NCT06498635

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Jefferson Torresdale Hospital (Philadelphia, PA); Thomas Jefferson University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    10 sites within 50 mi
  5. Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

    NCT06616584

    • Phase 2/3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Fox Chase Cancer Center (Philadelphia, PA); Temple University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  6. Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

    NCT04181060

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Fox Chase Cancer Center (Philadelphia, PA); Lankenau Medical Center (Wynnewood, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  7. Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

    NCT06096844

    • Phase 3
    • Ages 70 years and older
    • Sex: All

    Nearest sites: ECOG-ACRIN Cancer Research Group (Philadelphia, PA); Lankenau Medical Center (Wynnewood, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  8. The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

    NCT05502523

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Jefferson Health Northeast (Philadelphia, PA); Thomas Jefferson University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  9. A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

    NCT06667076

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Jefferson Health Northeast (Philadelphia, PA); Thomas Jefferson University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  10. Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

    NCT06890598

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Jefferson Hospital Northeast (Philadelphia, PA); Thomas Jefferson University, Sidney Kimmel Cancer Center - Clinical Trials Office (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  11. Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulES

    NCT05968898

    • Interventional
    • Ages 35 to 89 years
    • Sex: All

    Nearest sites: Penn Medicine University City (Philadelphia, PA); Penn Medicine Washington Square (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  12. Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

    NCT06122077

    • Observational
    • Ages 50 years and older
    • Sex: All

    Nearest sites: Temple University (Philadelphia, PA); Inspira Medical Center (Mullica Hill, NJ)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  13. Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

    NCT06422143

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Thomas Jefferson University - Clinical Research Institute ( Site 0147) (Philadelphia, PA); Capital Health Medical Center - Hopewell ( Site 0034) (Pennington, NJ)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  14. A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

    NCT06868277

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Research Site (Philadelphia, PA); Research Site (Newark, DE)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  15. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    NCT03452774

    • Observational
    • Ages Any age
    • Sex: All

    Nearest sites: Massive Bio SYNERGY-AI site (Philadelphia, PA); Massive Bio SYNERGY-AI site (Newark, DE)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  16. The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

    NCT04585750

    • Phase 1/2
    • Ages 12 years and older
    • Sex: All

    Nearest sites: Abramson Cancer Center of the University of Pennsylvania (Philadelphia, PA); Medical Oncology Hematology Consultants (Newark, DE)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  17. Empathic Communication Skills (ECS) Training

    NCT05456841

    • Interventional
    • Ages 18 to 100 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Fox Chase Cancer Center (Data Collection Only) (Philadelphia, PA); University of Pennsylvania (Data Collection Only) (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  18. A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

    NCT06119581

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Thomas Jefferson University, Sidney Kimmel Cancer Center - Clinical Trials Office (Philadelphia, PA); USO - Alliance Cancer Specialists, PC (Horsham, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  19. A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

    NCT06362252

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Thomas Jefferson University Hospital - Central (Philadelphia, PA); University of Pennsylvania, Abramson Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  20. CT-95 in Advanced Cancers Associated With Mesothelin Expression

    NCT06756035

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Context Investigational Site (Philadelphia, PA); University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  21. Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

    NCT06767514

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Clinical Study Site (Philadelphia, PA); Clinical Study Site (Mullica Hill, NJ)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  22. A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

    NCT06778863

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Fox Chase Cancer Center (Philadelphia, PA); Thomas Jefferson University, Sidney Kimmel Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  23. A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

    NCT07182149

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Normunity Investigational Site (Philadelphia, PA); Normunity Investigational Site (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  24. A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

    NCT03526835

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

    NCT03546829

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

    NCT04165070

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Abramson Cancer Center of the University of Pennsylvania ( Site 0010) (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)

    NCT04165798

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Abramson Cancer Center of the University of Pennsylvania ( Site 0010) (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

    NCT04332367

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Abramson Cancer Center of the University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy

    NCT04691817

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Abramson Cancer Center of the University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

    NCT04777994

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Perelman Center for Advanced Medicine /ID# 250188 (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

    NCT05059444

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

    NCT05098132

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Fox Chase Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

    NCT05176483

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Exelixis Clinical Site #98 (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

    NCT05456256

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Fox Chase Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking

    NCT05679349

    • Interventional
    • Ages 50 to 77 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Sidney Kimmel Cancer Center at Thomas Jefferson University (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial

    NCT05775939

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Thomas Jefferson University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

    NCT05800587

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Fox Chase Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

    NCT05948865

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Fox Chase Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

    NCT06043817

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Thomas Jefferson University Research Facility (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

    NCT06179160

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Jefferson University Hospitals (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

    NCT06216301

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Abramson Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

    NCT06218914

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Research Site (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

    NCT06244771

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. A Registry for People With Lung Cancer

    NCT06424327

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Thomas Jefferson University Hospital (Data Collection Only) (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

    NCT06586957

    • Phase 1
    • Ages 19 years and older
    • Sex: All

    Nearest site: Sidney Kimmell Cancer Center - Jefferson Health (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

    NCT06667908

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Pennsylvania (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

    NCT06681220

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

    NCT06686771

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Thomas Jefferson University Hospital (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

    NCT06706076

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Thomas Jefferson University, Sidney Kimmel Cancer Center (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  50. A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

    NCT06731907

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Abramson Cancer Center ( Site 0010) (Philadelphia, PA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Lung Cancer clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.