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The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

NCT05502523

This study is recruiting at 4 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

This clinical trial compares the effect of pulmonary vein-first surgical technique to pulmonary artery-first surgical technique in decreasing circulating tumor cell deoxyribonucleic acid (ctDNA) in patients with stage I-III non-small cell lung cancer. Pulmonary vein first and pulmonary artery first surgical techniques are standard surgical techniques for the division of the blood vessels during lung resection surgery. Pulmonary vein-first surgical technique may reduce the risk of shedding tumor cells during surgery and influence long term overall survival.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Lung Non-Small Cell Carcinoma
  • Stage I Lung Cancer AJCC v8
  • Stage II Lung Cancer AJCC v8
  • Stage III Lung Cancer AJCC v8

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Thomas Jefferson University
Last updated on ClinicalTrials.gov
January 23, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Pennsylvania · 4

  • Abington Memorial Hospital · Abington, PA
  • Jefferson Health Northeast · Philadelphia, PA
  • Thomas Jefferson University Hospital · Philadelphia, PA
  • Asplundh Cancer Pavilion at Jefferson Health · Willow Grove, PA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.