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A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

NCT06868277

This study is recruiting at 27 US sites in 15 states, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of ARTEMIDE-Lung04 is to assess the efficacy and safety of rilvegostomig compared with pembrolizumab monotherapy as 1L treatment in participants with mNSCLC and whose tumors express PD-L1.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Carcinoma, Non-Small Cell Lung

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
AstraZeneca
Last updated on ClinicalTrials.gov
September 25, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Delaware · 1

  • Research Site · Newark, DE

Florida · 4

  • Research Site · Bay Pines, FL
  • Research Site · Clearwater, FL
  • Research Site · Gainesville, FL
  • Research Site · St. Petersburg, FL

Georgia · 1

  • Research Site · Marietta, GA

Illinois · 2

  • Research Site · Chicago, IL
  • Research Site · Decatur, IL

Iowa · 1

  • Research Site · Des Moines, IA

Kansas · 1

  • Research Site · Leawood, KS

Kentucky · 1

  • Research Site · Owensboro, KY

Maryland · 4

  • Research Site · Bethesda, MD
  • Research Site · Frederick, MD
  • Research Site · Silver Spring, MD
  • Research Site · Towson, MD

Missouri · 1

  • Research Site · Bridgeton, MO

Nebraska · 1

  • Research Site · Lincoln, NE

Nevada · 1

  • Research Site · Reno, NV

New York · 4

  • Research Site · Buffalo, NY
  • Research Site · East Syracuse, NY
  • Research Site · Fresh Meadows, NY
  • Research Site · Westbury, NY

Pennsylvania · 2

  • Research Site · Fountain Hill, PA
  • Research Site · Philadelphia, PA

Washington · 1

  • Research Site · Aberdeen, WA

West Virginia · 2

  • Research Site · Charleston, WV
  • Research Site · Morgantown, WV

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.