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Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

NCT06686771

This study is recruiting at 71 US sites in 18 states, according to its ClinicalTrials.gov record last updated .

Summary

This study is being done to answer the following question: Can the chance of lung cancer growing or spreading be lowered by adding targeted radiotherapy to the usual combination of drugs? This study is being done to find out if this approach is better or worse than the usual approach for lung cancer. The usual approach is defined as the care most people get for non-small cell lung cancer.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Non-small Cell Lung Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Canadian Cancer Trials Group
Last updated on ClinicalTrials.gov
July 14, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 1

  • Mayo Clinic Hospital in Arizona · Phoenix, AZ

California · 2

  • City of Hope Comprehensive Cancer Center · Duarte, CA
  • City of Hope at Irvine Lennar · Irvine, CA

Colorado · 1

  • Saint Mary's Hospital and Regional Medical Center · Grand Junction, CO

Georgia · 1

  • CTCA at Southeastern Regional Medical Center · Newnan, GA

Idaho · 4

  • Saint Luke's Cancer Institute - Boise · Boise, ID
  • Saint Luke's Cancer Institute - Fruitland · Fruitland, ID
  • Saint Luke's Cancer Institute - Meridian · Meridian, ID
  • Saint Luke's Cancer Institute - Nampa · Nampa, ID

Illinois · 14

  • Alton Memorial Hospital · Alton, IL
  • Northwestern University · Chicago, IL
  • Decatur Memorial Hospital · Decatur, IL
  • Northwestern Medicine Cancer Center Kishwaukee · DeKalb, IL
  • Crossroads Cancer Center · Effingham, IL
  • Northwestern Medicine Cancer Center Delnor · Geneva, IL
  • Northwestern Medicine Glenview Outpatient Center · Glenview, IL
  • Northwestern Medicine Grayslake Outpatient Center · Grayslake, IL
  • Northwestern Medicine Lake Forest Hospital · Lake Forest, IL
  • HSHS Saint Elizabeth's Hospital · O'Fallon, IL
  • Northwestern Medicine Oak Brook · Oak Brook, IL
  • Northwestern Medicine Orland Park · Orland Park, IL
  • Memorial Hospital East · Shiloh, IL
  • Northwestern Medicine Cancer Center Warrenville · Warrenville, IL

Iowa · 10

  • UI Health Care Mission Cancer and Blood - Ankeny Clinic · Ankeny, IA
  • Mercy Hospital · Cedar Rapids, IA
  • Oncology Associates at Mercy Medical Center · Cedar Rapids, IA
  • UI Health Care Mission Cancer and Blood - West Des Moines Clinic · Clive, IA
  • Iowa Methodist Medical Center · Des Moines, IA
  • Mercy Medical Center - Des Moines · Des Moines, IA
  • UI Health Care Mission Cancer and Blood - Des Moines Clinic · Des Moines, IA
  • UI Health Care Mission Cancer and Blood - Laurel Clinic · Des Moines, IA
  • UI Healthcare Mission Cancer and Blood - Pella · Pella, IA
  • UI Health Care Mission Cancer and Blood - Waukee Clinic · Waukee, IA

Minnesota · 3

  • Miller-Dwan Hospital · Duluth, MN
  • Mayo Clinic in Rochester · Rochester, MN
  • Coborn Cancer Center at Saint Cloud Hospital · Saint Cloud, MN

Missouri · 6

  • Saint Francis Medical Center · Cape Girardeau, MO
  • Siteman Cancer Center at Saint Peters Hospital · City of Saint Peters, MO
  • Siteman Cancer Center at West County Hospital · Creve Coeur, MO
  • Siteman Cancer Center at Christian Hospital · St Louis, MO
  • Siteman Cancer Center-South County · St Louis, MO
  • Washington University School of Medicine · St Louis, MO

Nebraska · 3

  • Nebraska Medicine-Bellevue · Bellevue, NE
  • Nebraska Medicine-Village Pointe · Omaha, NE
  • University of Nebraska Medical Center · Omaha, NE

New York · 12

  • Northwell Health/Center for Advanced Medicine · Lake Success, NY
  • Lenox Hill Hospital · New York, NY
  • Manhattan Eye Ear and Throat Hospital · New York, NY
  • Mount Sinai Chelsea · New York, NY
  • Mount Sinai Hospital · New York, NY
  • Mount Sinai West · New York, NY
  • Queens Cancer Center · Rego Park, NY
  • University of Rochester · Rochester, NY
  • Stony Brook University Medical Center · Stony Brook, NY
  • State University of New York Upstate Medical University · Syracuse, NY
  • Montefiore Medical Center - Moses Campus · The Bronx, NY
  • Montefiore Medical Center-Einstein Campus · The Bronx, NY

Ohio · 1

  • Ohio State University Comprehensive Cancer Center · Columbus, OH

Oklahoma · 1

  • University of Oklahoma Health Sciences Center · Oklahoma City, OK

Pennsylvania · 7

  • Geisinger Medical Center · Danville, PA
  • Penn State Milton S Hershey Medical Center · Hershey, PA
  • Geisinger Medical Oncology-Lewisburg · Lewisburg, PA
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion · Mechanicsburg, PA
  • Thomas Jefferson University Hospital · Philadelphia, PA
  • UPMC-Shadyside Hospital · Pittsburgh, PA
  • Geisinger Wyoming Valley/Henry Cancer Center · Wilkes-Barre, PA

Tennessee · 1

  • Vanderbilt University/Ingram Cancer Center · Nashville, TN

Texas · 1

  • The Don and Sybil Harrington Cancer Center · Amarillo, TX

Virginia · 2

  • VCU Massey Cancer Center at Stony Point · Richmond, VA
  • VCU Massey Comprehensive Cancer Center · Richmond, VA

Wisconsin · 1

  • Northwest Wisconsin Cancer Center · Ashland, WI

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.