LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
NCT06216301
This study is recruiting at 38 US sites in 13 states, according to its ClinicalTrials.gov record last updated .
Summary
This study, known as LUNAR-2, aims to investigate the effectiveness and safety of using TTFields, delivered by the NovoTTF-200T device, concomitantly administered with pembrolizumab and platinum-based chemotherapy for patients with advanced non-small cell lung cancer that has spread to other parts of the body. The primary goals of the study are to assess overall survival and progression-free survival. Secondary objectives include analyzing outcomes based on the specific histology (subtype) of the lung cancer.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Metastatic Non-small Cell Lung Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- NovoCure GmbH
- Last updated on ClinicalTrials.gov
- October 6, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- Central Alabama Research · Birmingham, AL
Arizona · 1
- Western Regional Medical Center, LLC · Goodyear, AZ
California · 3
- St. Jude Herritage Medical Group · Fullerton, CA
- Hoag Family Cancer Institute - Hoag Memorial Hospital · Newport Beach, CA
- Sutter Institute for Medical Research · Sacramento, CA
Florida · 3
- Baptist MD Anderson Cancer Center, Baptist Health · Jacksonville, FL
- Florida Cancer Affiliates - Ocala Oncology · Ocala, FL
- Moffitt Cancer Center · Tampa, FL
Illinois · 4
- Northwest Oncology & Hematology · Barrington, IL
- Elmhurst Hospital Nancy Knowles Cancer Center · Elmhurst, IL
- Edward Cancer Center · Naperville, IL
- Cancer Treatment Centers of America (CTCA) · Zion, IL
Indiana · 2
- Parkview Packnett Family Cancer Institute · Fort Wayne, IN
- Franciscan Health Indianapolis · Indianapolis, IN
Kansas · 1
- University of Kansas Cancer Center · Westwood, KS
Missouri · 4
- Luminis Health Radiation Oncology - Anne Arundel Health System · Annapolis, MO
- University of Kansas Cancer Center - North · Kansas City, MO
- University of Kansas Cancer Center - Lee's Summit · Lee's Summit, MO
- University of Kansas Cancer Center - Overland Park · Overland, MO
New York · 5
- New York Cancer & Blood Specialists (NYCBS) · New Hyde Park, NY
- New York Cancer & Blood Specialists (NYCBS) · New York, NY
- University of Rochester Medical Center · Rochester, NY
- New York Cancer & Blood Specialists (NYCBS) · Shirley, NY
- New York Cancer & Blood Specialists (NYCBS) · The Bronx, NY
North Carolina · 1
- WakeMed Health & Hospitals · Cary, NC
Pennsylvania · 2
- Abramson Cancer Center · Philadelphia, PA
- AHN Cancer Center · Pittsburgh, PA
Texas · 6
- Old Parkland Hospital Hematology Oncology Clinic · Dallas, TX
- UT Southwestern Medical Center · Dallas, TX
- DHR Health Oncology Institute · Edinburg, TX
- Houston Methodist Cancer Center · Houston, TX
- Methodist Richardson Cancer Center · Richardson, TX
- Jason Bates at University of Texas Health Science Center · San Antonio, TX
Washington · 5
- MultiCare Regional Cancer Center · Auburn, WA
- MultiCare Regional Cancer Center · Gig Harbor, WA
- MultiCare Regional Cancer Center · Puyallup, WA
- MultiCare Deaconess Cancer and Blood Specialty Center - Downtown · Spokane, WA
- MultiCare Institute for Research & Innovation · Tacoma, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.