Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
NCT05174169
This study is recruiting at 922 US sites in 49 states, according to its ClinicalTrials.gov record last updated .
Summary
This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon cancer.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Stage III Colon Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2/3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- NRG Oncology
- Last updated on ClinicalTrials.gov
- September 2, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 3
- Thomas Hospital · Fairhope, AL
- Mobile Infirmary Medical Center · Mobile, AL
- University of South Alabama Mitchell Cancer Institute · Mobile, AL
Arizona · 4
- Kingman Regional Medical Center · Kingman, AZ
- Cancer Center at Saint Joseph's · Phoenix, AZ
- Banner University Medical Center - Tucson · Tucson, AZ
- University of Arizona Cancer Center-North Campus · Tucson, AZ
Arkansas · 3
- Mercy Hospital Fort Smith · Fort Smith, AR
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro · Jonesboro, AR
- University of Arkansas for Medical Sciences · Little Rock, AR
California · 103
- Kaiser Permanente-Anaheim · Anaheim, CA
- Kaiser Permanente-Deer Valley Medical Center · Antioch, CA
- Mission Hope Medical Oncology - Arroyo Grande · Arroyo Grande, CA
- PCR Oncology · Arroyo Grande, CA
- Sutter Auburn Faith Hospital · Auburn, CA
- Sutter Cancer Centers Radiation Oncology Services-Auburn · Auburn, CA
- AIS Cancer Center at San Joaquin Community Hospital · Bakersfield, CA
- Kaiser Permanente-Baldwin Park · Baldwin Park, CA
- Kaiser Permanente-Bellflower · Bellflower, CA
- Alta Bates Summit Medical Center-Herrick Campus · Berkeley, CA
- Tower Cancer Research Foundation · Beverly Hills, CA
- Mills-Peninsula Medical Center · Burlingame, CA
- Marshall Cancer Center · Cameron Park, CA
- Sutter Cancer Centers Radiation Oncology Services-Cameron Park · Cameron Park, CA
- Mercy Cancer Center - Carmichael · Carmichael, CA
- Mercy San Juan Medical Center · Carmichael, CA
- Eden Hospital Medical Center · Castro Valley, CA
- Enloe Medical Center · Chico, CA
- Sutter Davis Hospital · Davis, CA
- City of Hope Comprehensive Cancer Center · Duarte, CA
- Kaiser Permanente Dublin · Dublin, CA
- Mercy Cancer Center - Elk Grove · Elk Grove, CA
- Kaiser Permanente-Fontana · Fontana, CA
- Orange Coast Memorial Medical Center · Fountain Valley, CA
- Kaiser Permanente-Fremont · Fremont, CA
- Palo Alto Medical Foundation-Fremont · Fremont, CA
- Washington Health · Fremont, CA
- Kaiser Permanente Fresno Orchard Plaza · Fresno, CA
- Kaiser Permanente-Fresno · Fresno, CA
- Kaiser Permanente South Bay · Harbor City, CA
- City of Hope at Irvine Lennar · Irvine, CA
- Kaiser Permanente-Irvine · Irvine, CA
- UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care · Irvine, CA
- Saddleback Memorial Medical Center · Laguna Hills, CA
- UCI Health Laguna Hills · Laguna Hills, CA
- Loma Linda University Medical Center · Loma Linda, CA
- Veterans Affairs Loma Linda Healthcare System · Loma Linda, CA
- Long Beach Memorial Medical Center-Todd Cancer Institute · Long Beach, CA
- Cedars-Sinai Medical Center · Los Angeles, CA
- Kaiser Permanente Los Angeles Medical Center · Los Angeles, CA
- Kaiser Permanente West Los Angeles · Los Angeles, CA
- Keck Medicine of USC Koreatown · Los Angeles, CA
- Los Angeles General Medical Center · Los Angeles, CA
- USC / Norris Comprehensive Cancer Center · Los Angeles, CA
- Fremont - Rideout Cancer Center · Marysville, CA
- Kaiser Permanente- Modesto MOB II · Modesto, CA
- Kaiser Permanente-Modesto · Modesto, CA
- Memorial Medical Center · Modesto, CA
- Palo Alto Medical Foundation-Camino Division · Mountain View, CA
- Palo Alto Medical Foundation-Gynecologic Oncology · Mountain View, CA
- USC Norris Oncology/Hematology-Newport Beach · Newport Beach, CA
- Sutter Cancer Research Consortium · Novato, CA
- Kaiser Permanente-Oakland · Oakland, CA
- Kaiser Permanente-Ontario · Ontario, CA
- Saint Joseph Hospital - Orange · Orange, CA
- UC Irvine Health/Chao Family Comprehensive Cancer Center · Orange, CA
- Palo Alto Medical Foundation Health Care · Palo Alto, CA
- Kaiser Permanente - Panorama City · Panorama City, CA
- Eisenhower Medical Center · Rancho Mirage, CA
- Kaiser Permanente- Marshall Medical Offices · Redwood City, CA
- Kaiser Permanente-Richmond · Richmond, CA
- Kaiser Permanente-Riverside · Riverside, CA
- Mercy Cancer Center - Rocklin · Rocklin, CA
- Kaiser Permanente-Roseville · Roseville, CA
- Sutter Cancer Centers Radiation Oncology Services-Roseville · Roseville, CA
- Sutter Roseville Medical Center · Roseville, CA
- Kaiser Permanente Downtown Commons · Sacramento, CA
- Kaiser Permanente-South Sacramento · Sacramento, CA
- Mercy Cancer Center - Sacramento · Sacramento, CA
- Sutter Medical Center Sacramento · Sacramento, CA
- University of California Davis Comprehensive Cancer Center · Sacramento, CA
- Salinas Valley Memorial · Salinas, CA
- Kaiser Permanente-San Diego Zion · San Diego, CA
- California Pacific Medical Center-Pacific Campus · San Francisco, CA
- Kaiser Permanente-San Francisco · San Francisco, CA
- Kaiser Permanente-Santa Teresa-San Jose · San Jose, CA
- Kaiser Permanente San Leandro · San Leandro, CA
- Pacific Central Coast Health Center-San Luis Obispo · San Luis Obispo, CA
- Kaiser Permanente-San Marcos · San Marcos, CA
- Mills Health Center · San Mateo, CA
- Kaiser San Rafael-Gallinas · San Rafael, CA
- Ridley-Tree Cancer Center · Santa Barbara, CA
- Kaiser Permanente Medical Center - Santa Clara · Santa Clara, CA
- Palo Alto Medical Foundation-Santa Cruz · Santa Cruz, CA
- Santa Cruz Radiation Oncology Medical Group · Santa Cruz, CA
- Mission Hope Medical Oncology - Santa Maria · Santa Maria, CA
- Kaiser Permanente-Santa Rosa · Santa Rosa, CA
- Sutter Pacific Medical Foundation · Santa Rosa, CA
- City of Hope South Pasadena · South Pasadena, CA
- Kaiser Permanente-South San Francisco · South San Francisco, CA
- Kaiser Permanente-Stockton · Stockton, CA
- Palo Alto Medical Foundation-Sunnyvale · Sunnyvale, CA
- City of Hope South Bay · Torrance, CA
- Torrance Memorial Physician Network - Cancer Care · Torrance, CA
- Gene Upshaw Memorial Tahoe Forest Cancer Center · Truckee, CA
- City of Hope Upland · Upland, CA
- Kaiser Permanente Medical Center-Vacaville · Vacaville, CA
- Kaiser Permanente-Vallejo · Vallejo, CA
- Sutter Solano Medical Center/Cancer Center · Vallejo, CA
- John Muir Medical Center-Walnut Creek · Walnut Creek, CA
- Kaiser Permanente-Walnut Creek · Walnut Creek, CA
- Woodland Memorial Hospital · Woodland, CA
- Kaiser Permanente-Woodland Hills · Woodland Hills, CA
Colorado · 29
- UCHealth University of Colorado Hospital · Aurora, CO
- Intermountain Health Platte Valley Hospital · Brighton, CO
- Memorial Hospital North · Colorado Springs, CO
- Penrose-Saint Francis Healthcare · Colorado Springs, CO
- Rocky Mountain Cancer Centers-Penrose · Colorado Springs, CO
- Saint Francis Cancer Center · Colorado Springs, CO
- UCHealth Memorial Hospital Central · Colorado Springs, CO
- Denver Health Medical Center · Denver, CO
- Kaiser Permanente-Franklin · Denver, CO
- Saint Joseph Hospital - Cancer Centers of Colorado · Denver, CO
- UCHealth - Cherry Creek · Denver, CO
- Dillon Health Center/Shaw Cancer Center · Dillon, CO
- CommonSpirit Cancer Center Mercy · Durango, CO
- Mercy Medical Center · Durango, CO
- Shaw Cancer Center · Edwards, CO
- Cancer Care and Hematology-Fort Collins · Fort Collins, CO
- Poudre Valley Hospital · Fort Collins, CO
- Lutheran Hospital - Cancer Centers of Colorado · Golden, CO
- Grand Valley Oncology · Grand Junction, CO
- Saint Mary's Hospital and Regional Medical Center · Grand Junction, CO
- UCHealth Greeley Hospital · Greeley, CO
- UCHealth Highlands Ranch Hospital · Highlands Ranch, CO
- Kaiser Permanente-Rock Creek · Lafayette, CO
- CommonSpirit Saint Anthony Hospital Cancer Center · Lakewood, CO
- Kaiser Permanente-Lone Tree · Lone Tree, CO
- UCHealth Lone Tree Health Center · Lone Tree, CO
- Longmont United Hospital · Longmont, CO
- Medical Center of the Rockies · Loveland, CO
- Saint Mary Corwin Medical Center · Pueblo, CO
Connecticut · 8
- Danbury Hospital · Danbury, CT
- Smilow Cancer Hospital-Derby Care Center · Derby, CT
- Smilow Cancer Hospital Care Center-Fairfield · Fairfield, CT
- Smilow Cancer Hospital Care Center at Glastonbury · Glastonbury, CT
- Smilow Cancer Hospital Care Center at Greenwich · Greenwich, CT
- Smilow Cancer Hospital Care Center - Guilford · Guilford, CT
- Smilow Cancer Hospital Care Center at Saint Francis · Hartford, CT
- Smilow Cancer Center/Yale-New Haven Hospital · New Haven, CT
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.