A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
NCT07164443
This study is recruiting at 52 US sites in 23 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to evaluate the overall survival (length of time from the start of study to date of death from any cause) for pasritamig (JNJ-78278343) in Part 1 in combination with best supportive care (BSC) and in Part 2 with JNJ-87189401+BSC as compared to placebo with BSC in participants with metastatic castration-resistant prostate cancer (mCRPC; a stage of cancer that has spread beyond the prostate gland and is no longer responding to hormone therapies).
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Metastatic Castration-resistant Prostatic Neoplasms
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- Male
- Healthy volunteers
- Not accepted
- Sponsor
- Janssen Research & Development, LLC
- Last updated on ClinicalTrials.gov
- September 25, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 4
- University of California at San Diego · La Jolla, CA
- Cedars Sinai Medical Center · Los Angeles, CA
- Ronald Reagan UCLA Medical Center · Los Angeles, CA
- San Francisco VA Medical Center · San Francisco, CA
Colorado · 3
- Rocky Mountain Cancer Centers · Aurora, CO
- University of Colorado Cancer Center · Aurora, CO
- Colorado Clinical Research · Lakewood, CO
Connecticut · 1
- Hartford Hospital · Hartford, CT
District of Columbia · 1
- Johns Hopkins Office of Capital Region Research - Sibley Memorial Hospital · Washington D.C., DC
Florida · 3
- Bay Pines VA Healthcare System · Bay Pines, FL
- Florida Cancer Specialists & Research Institute · Fort Myers, FL
- Moffitt Cancer Center · Tampa, FL
Iowa · 2
- University of Iowa Hospital and Clinics · Iowa City, IA
- Mission Cancer Blood · Waukee, IA
Louisiana · 1
- East Jefferson General Hospital · Metairie, LA
Maryland · 1
- Johns Hopkins University · Baltimore, MD
Massachusetts · 1
- Dana Farber Cancer Institute · Boston, MA
Michigan · 2
- University of Michigan Health System · Ann Arbor, MI
- Henry Ford Cancer Detroit · Detroit, MI
Minnesota · 1
- University Of Minnesota Medical Center · Minneapolis, MN
Nebraska · 1
- XCancer Omaha / Urology Cancer Center · Omaha, NE
New York · 4
- NYU Langone Hospitals · Brooklyn, NY
- NYU Langone Hospital Long Island · Mineola, NY
- Columbia University Medical Center · New York, NY
- NYU Langone Health Laura and Isaac Perlmutter Cancer Center · New York, NY
North Carolina · 2
- Levine Cancer Institute · Charlotte, NC
- Atrium Health Wake Forest Baptist Comprehensive Cancer Center · Winston-Salem, NC
Ohio · 2
- University of Cincinnati · Cincinnati, OH
- University Hospital of Cleveland · Cleveland, OH
Oregon · 2
- VA Portland Health Care System · Portland, OR
- Oregon Urology Institute · Springfield, OR
Pennsylvania · 4
- MidLantic Urology · Bala-Cynwyd, PA
- Keystone Urology Specialists · Lancaster, PA
- Penn Medicine Abramson Cancer Center · Philadelphia, PA
- UPMC Cancer Centers · Pittsburgh, PA
South Carolina · 4
- Ralph H Johnson Veterans Hospital · Charleston, SC
- Gibbs Cancer Center and Research Institute Pelham · Greer, SC
- Carolina Urologic Research Center · Myrtle Beach, SC
- Gibbs Cancer Center · Spartanburg, SC
Tennessee · 2
- Tennessee Oncology - Chattanooga · Chattanooga, TN
- Tennessee Oncology Nashville · Nashville, TN
Texas · 4
- UT Southwestern Medical Center · Dallas, TX
- MD Anderson Cancer Center · Houston, TX
- Michael E DeBakey VA Medical Center · Houston, TX
- Texas Oncology West Texas · Wichita Falls, TX
Utah · 1
- Utah Cancer Specialists · Salt Lake City, UT
Virginia · 3
- Virginia Cancer Specialists · Fairfax, VA
- Virginia Oncology Associates · Norfolk, VA
- Blue Ridge Cancer Care · Roanoke, VA
Washington · 3
- Fred Hutchinson Cancer Research Center · Seattle, WA
- University of Washington · Seattle, WA
- VA Puget Sound Healthcare System · Seattle, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.