DESTINY-PANTUMOUR04
NCT07124000
This study is recruiting at 18 US sites in 13 states, according to its ClinicalTrials.gov record last updated .
Summary
This study will evaluate the effectiveness of T-DXd in patients with HER2-positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have received prior systemic treatment for metastatic or advanced disease and have no satisfactory alternative treatment options in a real-world setting in the US
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Adenocarcinoma (NOS)
- Anal Cancer
- Bladder Cancer
- Cervical Cancer
- Endometrial Cancer
- Esophageal Cancer
- Gall Bladder Cancer
- Gastrointestinal Stromal Tumour
- Head and Neck Cancer
- Liver Cancer
- Melanoma
- Mouth Cancer
- Nasopharangeal Cancer
- Neuroendocrine, Gastrointestinal Cancer
- Ovarian Cancer
- Pancreatic Cancer
- Prostate Cancer
- Renal Cell Carcinoma
- Salivary Gland Cancer
- Sarcoma
- Small Cell Lung Cancer
- Testicular Cancer
- Throat Cancer
- Thyroid Cancer
- Urethral Cancer
- Vaginal Cancer
- Vulvar Cancer
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- 18 to 130 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- AstraZeneca
- Last updated on ClinicalTrials.gov
- September 25, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- Research Site · Birmingham, AL
Arizona · 2
- Research Site · Bullhead City, AZ
- Research Site · Casa Grande, AZ
California · 1
- Research Site · San Diego, CA
Colorado · 1
- Research Site · Boulder, CO
Florida · 3
- Research Site · Coral Springs, FL
- Research Site · St. Petersburg, FL
- Research Site · West Palm Beach, FL
Illinois · 1
- Research Site · Decatur, IL
Kansas · 1
- Research Site · Topeka, KS
New Mexico · 1
- Research Site · Farmington, NM
North Carolina · 2
- Research Site · Durham, NC
- Research Site · Wilson, NC
Ohio · 2
- Research Site · Canton, OH
- Research Site · Maumee, OH
Pennsylvania · 1
- Research Site · Philadelphia, PA
Tennessee · 1
- Research Site · Nashville, TN
Texas · 1
- Research Site · Dallas, TX
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.