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Prostate Cancer Clinical Trials near Orange, CA

132 studies for Prostate Cancer are recruiting at 266 sites within 50 miles of Orange, California, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Prostate Cancer trials in the US or all trials near Orange.

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Recruiting now

Prostate Cancer studies enrolling near Orange

Showing the 50 nearest of 132 studies.
  1. Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

    NCT06592924

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: UC Irvine Health/Chao Family Comprehensive Cancer Center (Orange, CA); Kaiser Permanente-Anaheim (Anaheim, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    28 sites within 50 mi
  2. A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

    NCT06925737

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0006) (Orange, CA); City of Hope Lennar Foundation Cancer Center ( Site 0059) (Irvine, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  3. Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

    NCT05946213

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: UC Irvine Health/Chao Family Comprehensive Cancer Center (Orange, CA); UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care (Irvine, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  4. A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

    NCT07213674

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: University of California Irvine (Orange, CA); Providence Saint Jude Medical Center (Fullerton, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  5. Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

    NCT05983432

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest sites: University of California Irvine Medical Center (Orange, CA); City of Hope Cancer Center (Duarte, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  6. A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

    NCT06136650

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0040) (Orange, CA); CHAO Family Comprehensive Cancer Center and Ambulatory Care ( Site 0120) (Irvine, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  7. Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

    NCT07200830

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: UC Irvine Health/Chao Family Comprehensive Cancer Center (Orange, CA); City of Hope at Irvine Lennar (Irvine, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  8. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    NCT03452774

    • Observational
    • Ages Any age
    • Sex: All

    Nearest sites: Massive Bio SYNERGY-AI site (Orange, CA); Massive Bio SYNERGY-AI site (Irvine, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  9. Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer

    NCT05997615

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: UCI Health Chao Family Comprehensive Cancer Center (Orange, CA); Lennar Foundation Cancer Center (Irvine, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  10. Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

    NCT06056830

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: UC Irvine Health (Orange, CA); Greater Los Angeles VA Medical Center (Los Angeles, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  11. Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

    NCT05803941

    • Phase 4
    • Ages 18 to 100 years
    • Sex: Male

    Nearest sites: St. Joseph Hospital (Orange, CA); Providence Saint Johns Health Ctr (Santa Monica, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  12. A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer

    NCT06609005

    • Phase 1/2
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: UC Irvine Medical Center (Orange, CA); Hoag Family Cancer Institute (Newport Beach, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  13. Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

    NCT06632977

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: UC Irvine Health/Chao Family Comprehensive Cancer Center (Orange, CA); UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care (Irvine, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  14. A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

    NCT06863272

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: University of California-Irvine Medical Center ( Site 0016) (Orange, CA); UCLA Hematology & Oncology ( Site 0003) (Los Angeles, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  15. Impact of Intraoperative ICG on Functional Outc in RARP

    NCT06446648

    • Early Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Chao Family Comprehensive Cancer Center University of California, Irvine (Orange, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

    NCT06580002

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Chao Family Comprehensive Cancer Center, University of California Irvine (Orange, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

    NCT06855277

    • Phase 3
    • Ages 18 to 100 years
    • Sex: Male

    Nearest site: Univ Cali Irvine ALS Neuromuscular (Orange, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

    NCT06629779

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Los Angeles Cancer Network (LACN) (Anaheim, CA); Los Angeles Cancer Network (LACN) (Fountain Valley, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  19. A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

    NCT04729114

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Los Angeles Cancer Network (Anaheim, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

    NCT04221542

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Providence Saint Jude Medical Center (Fullerton, CA); City of Hope National Medical Center (Duarte, CA)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  21. A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

    NCT07225946

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: MemorialCare Orange Coast Medical Center (Fountain Valley, CA); Cancer and Blood Specialty Clinic (Los Alamitos, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  22. SBRT Boost for Unfavorable Prostate Cancer'

    NCT02016248

    • Interventional
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Orange Coast Memorial Medical Center (Fountain Valley, CA); Saddleback Memorial Medical Center (Laguna Hills, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  23. A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

    NCT06785636

    • Phase 1/2
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: MemorialCare Orange Coast Medical Center (Fountain Valley, CA); Cancer and Blood Research Center (Los Alamitos, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  24. This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

    NCT07028853

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: UCLA Hematology/Oncology - Irvine (Irvine, CA); UCLA Hematology/Oncology - Laguna Hills (Laguna Hills, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    16 sites within 50 mi
  25. Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

    NCT05806515

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: City of Hope at Irvine Lennar (Irvine, CA); City of Hope Comprehensive Cancer Center (Duarte, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  26. Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

    NCT05804318

    • Interventional
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: City of Hope Orange County Lennar Foundation Cancer Center (Irvine, CA); Duarte Cancer Center (Duarte, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  27. Study With [225Ac]Ac-FL-020 in mCRPC Participants

    NCT06492122

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Chao Family Comprehensive Cancer Center (Irvine, CA); City of Hope Medical Center (Duarte, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  28. Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate Cancer

    NCT07790718

    • Interventional
    • Ages 40 to 80 years
    • Sex: Male

    Nearest sites: City of Hope at Irvine Lennar (Irvine, CA); City of Hope Medical Center (Duarte, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  29. PyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer

    NCT04700332

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Hoag Memorial Hospital Presbyterian (Irvine, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. A Phase I Trial of 61Cu-NODAGA-PSMA for Patients with Prostate Cancer

    NCT06736054

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Hoag Memorial Hospital Presbyterian (Irvine, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

    NCT07581184

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Hoag Memorial Hospital Presbyterian (Irvine, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

    NCT03866382

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: USC Norris Oncology/Hematology-Newport Beach (Newport Beach, CA); Keck Medicine of USC Koreatown (Los Angeles, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  33. Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

    NCT05519449

    • Phase 1
    • Ages 18 to 100 years
    • Sex: Male

    Nearest sites: Hoag Memorial Hospital Presbyterian (Newport Beach, CA); UCLA Department of Medicine (Los Angeles, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  34. AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

    NCT07611110

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Research Site (Newport Beach, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer

    NCT04986423

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Innovative Clinical Research Institute (Whittier, CA); California Research Institute (Los Angeles, CA)

    Distance to nearest recruiting site
    ~17 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  36. Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

    NCT04423211

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: City of Hope Corona (Corona, CA); City of Hope Upland (Upland, CA)

    Distance to nearest recruiting site
    ~18 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  37. Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

    NCT03678025

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Tibor Rubin VA Medical Center (Long Beach, CA); City of Hope Comprehensive Cancer Center (Duarte, CA)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  38. Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

    NCT05334069

    • Observational
    • Ages 40 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Tibor Rubin VA Medical Center (Long Beach, CA); Providence Saint Joseph Medical Center/Disney Family Cancer Center (Burbank, CA)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  39. Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors

    NCT07080242

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest sites: MemorialCare Long Beach Medical Center (Long Beach, CA); Valkyrie Clinical Trials (Los Angeles, CA)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  40. Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

    NCT04787744

    • Phase 2/3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: VA Long Beach Healthcare System, Long Beach, CA (Long Beach, CA); VA Greater Los Angeles Healthcare System, West Los Angeles, CA (West Los Angeles, CA)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  41. Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

    NCT06470243

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Tibor Rubin VA Medical Center (Long Beach, CA)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. Study of AR Suppression With Carotuximab in Metastatic, Castration-Resistant Prostate Canc

    NCT05534646

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: City of Hope (Duarte, CA); Cedars-Sinai Medical Center (Los Angeles, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  43. A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

    NCT05652686

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: City of Hope (City of Hope National Medical Center, City of Hope Medical Center) (Duarte, CA); USC Norris Comprehensive Cancer Center (Los Angeles, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  44. Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes

    NCT05832086

    • Phase 2
    • Ages Any age
    • Sex: Male

    Nearest sites: Beckman Research Institute of the City of Hope (Duarte, CA); Cedars-Sinai Medical Center (Los Angeles, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  45. A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

    NCT06465069

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest sites: City of Hope National Medical Center (Duarte, CA); UCLA Department of Medicine-Hematology/Oncology (Los Angeles, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  46. A Study of LY4257496 in Participants With Cancer (OMNIRAY)

    NCT07114601

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest sites: City of Hope (Duarte, CA); University of California, Los Angeles (UCLA) (Santa Monica, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  47. Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

    NCT04472338

    • Observational
    • Ages 40 years and older
    • Sex: Male
    • Accepts healthy volunteers

    Nearest site: City of Hope (Duarte, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer

    NCT04734730

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: City of Hope Medical Center (Duarte, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. Study to Detect Changes in Urinary and Gut Microbiome During Androgen Deprivation Therapy and Radiation Therapy in Patients With Prostate Cancer

    NCT04775355

    • Observational
    • Ages 18 years and older
    • Sex: Male

    Nearest site: City of Hope Medical Center (Duarte, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  50. Clinical Trial of Approaches to Prostate Cancer Surgery

    NCT05155501

    • Interventional
    • Ages 40 to 80 years
    • Sex: Male

    Nearest site: Beckman Research Institute of City of Hope (Duarte, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Prostate Cancer clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.