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Prostate Cancer Clinical Trials near Chicago, IL

73 studies for Prostate Cancer are recruiting at 163 sites within 50 miles of Chicago, Illinois, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Prostate Cancer trials in the US or all trials near Chicago.

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Recruiting now

Prostate Cancer studies enrolling near Chicago

Showing the 50 nearest of 73 studies.
  1. Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

    NCT05946213

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Advocate Illinois Masonic Medical Center (Chicago, IL); Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    19 sites within 50 mi
  2. Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

    NCT05334069

    • Observational
    • Ages 40 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Advocate Illinois Masonic Medical Center (Chicago, IL); John H Stroger Jr Hospital of Cook County (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    18 sites within 50 mi
  3. Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

    NCT04423211

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Northwestern University (Chicago, IL); Rush MD Anderson Cancer Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    10 sites within 50 mi
  4. Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

    NCT06470243

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Northwestern University (Chicago, IL); University of Illinois (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    8 sites within 50 mi
  5. International Registry for Men With Advanced Prostate Cancer (IRONMAN)

    NCT03151629

    • Observational
    • Ages 21 years and older
    • Sex: Male

    Nearest sites: Robert H. Lurie Comprehensive Cancer Center of Northwestern University (Chicago, IL); University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  6. Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

    NCT03866382

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Rush MD Anderson Cancer Center (Chicago, IL); University of Chicago Comprehensive Cancer Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  7. Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

    NCT06592924

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: University of Illinois (Chicago, IL); Elmhurst Memorial Hospital (Elmhurst, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  8. Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

    NCT07200830

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Northwestern University (Chicago, IL); Northwestern Medicine Oak Brook (Oak Brook, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  9. Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

    NCT03678025

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Rush University Medical Center (Chicago, IL); University of Illinois (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  10. FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial

    NCT06244004

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Northwestern University (Chicago, IL); Northwestern University Oak Brook IL453 (Oak Brook, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  11. Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

    NCT06931340

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Rush MD Anderson Cancer Center (Chicago, IL); University of Illinois (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  12. An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

    NCT05939414

    • Phase 3
    • Ages 18 to 100 years
    • Sex: Male

    Nearest sites: University of Chicago (Chicago, IL); The Cancer Institute of Alexian Brothers (Elk Grove, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  13. Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial

    NCT06022822

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Northwestern University (Chicago, IL); University of Chicago Comprehensive Cancer Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  14. Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

    NCT06136624

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: University of Chicago Medical Center ( Site 0045) (Chicago, IL); University of Illinois at Chicago ( Site 0105) (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  15. Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

    NCT06855277

    • Phase 3
    • Ages 18 to 100 years
    • Sex: Male

    Nearest sites: Northwestern University (Chicago, IL); University of Illinois Cancer Center at Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  16. A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

    NCT06925737

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Rush University Medical Center-Hematology and Oncology ( Site 0028) (Chicago, IL); University of Illinois at Chicago-University of Illinois Cancer Center ( Site 0063) (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  17. A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

    NCT06952803

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: Research Site (Chicago, IL); Research Site (Chicago Ridge, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  18. A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

    NCT07213674

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest sites: University of Illinois Chicago (Chicago, IL); Midwestern Regional Medical Center dba City of Hope Chicago (Zion, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  19. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    NCT03452774

    • Observational
    • Ages Any age
    • Sex: All

    Nearest site: Massive Bio SYNERGY-AI site (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

    NCT04104776

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Chicago Medical Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

    NCT04373564

    • Phase 4
    • Ages 18 to 64 years
    • Sex: All

    Nearest site: University of Chicago Medical Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

    NCT04472338

    • Observational
    • Ages 40 years and older
    • Sex: Male
    • Accepts healthy volunteers

    Nearest site: Northwestern (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. A Study of NX-1607 in Adults With Advanced Malignancies

    NCT05107674

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. Clinical Trial of Approaches to Prostate Cancer Surgery

    NCT05155501

    • Interventional
    • Ages 40 to 80 years
    • Sex: Male

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

    NCT05176483

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Exelixis Clinical Site #26 (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

    NCT05417594

    • Phase 1/2
    • Ages 18 to 130 years
    • Sex: All

    Nearest site: Research Site (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

    NCT05519449

    • Phase 1
    • Ages 18 to 100 years
    • Sex: Male

    Nearest site: University of Chicago Medical Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss

    NCT05593497

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Jesse Brown VA Medical Center, Chicago, IL (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test

    NCT05629494

    • Phase 4
    • Ages 18 to 80 years
    • Sex: Male

    Nearest site: University of Chicago Medical Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

    NCT05691465

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy

    NCT05710380

    • Interventional
    • Ages 18 years and older
    • Sex: Male

    Nearest site: University of Chicago Medicine Comprehensive Cancer Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer

    NCT05726292

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: University of Chicago Comprehensive Cancer Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Prostate Cancer Treatment Using Androgen Deprivation Therapy and Focal Prostate Ablation

    NCT05790213

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: UChicago Medicine Comprehensive Cancer Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

    NCT05800665

    • Phase 1
    • Ages 18 years and older
    • Sex: Male

    Nearest site: University of Illinois Hospital & Health Sciences System (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance

    NCT05852041

    • Early Phase 1
    • Ages 18 years and older
    • Sex: Male
    • Accepts healthy volunteers

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

    NCT05983432

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Northwestern University Feinberg School of Medicine (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life

    NCT06171269

    • Interventional
    • Ages 18 years and older
    • Sex: Male

    Nearest site: University of Chicago Medicine Comprehensive Cancer Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

    NCT06172478

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Illinois Cancer Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. Geriatric Assessment and Technology Evaluation in Prostate Cancer

    NCT06215508

    • Observational
    • Ages 18 Minutes and older
    • Sex: Male

    Nearest site: o University of Chicago Medicine Comprehensive Cancer Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. Enzalutamide Implants (Enolen) in Patients With Prostate Cancer

    NCT06257693

    • Phase 1
    • Ages 21 years and older
    • Sex: Male

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

    NCT06274047

    • Phase 3
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Rush MD Anderson (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. GU-01: Glycyrrhizin in Prostate Cancer

    NCT06378346

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: University of Illinois (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

    NCT06395519

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Chicago Medical Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

    NCT06465069

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Chicago Hospital (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial

    NCT06499870

    • Phase 2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

    NCT06778863

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: The University of Chicago Comprehensive Cancer Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

    NCT06780670

    • Phase 2/3
    • Ages 18 to 100 years
    • Sex: Male

    Nearest site: University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

    NCT06785636

    • Phase 1/2
    • Ages 18 years and older
    • Sex: Male

    Nearest site: University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. An Investigational Scan (rhPSMA-7.3 PET/CT) for Detecting Biochemically Recurrent Prostate Cancer, ENLIGHTEN Trial

    NCT06813898

    • Early Phase 1
    • Ages Any age
    • Sex: Male

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  50. Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

    NCT06824818

    • Interventional
    • Ages 70 years and older
    • Sex: Male

    Nearest site: The University of Illinois at Chicago (UIC) (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Prostate Cancer clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.