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Obesity Clinical Trials near Orange, CA

67 studies for Obesity are recruiting at 134 sites within 50 miles of Orange, California, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Obesity trials in the US or all trials near Orange.

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Obesity studies enrolling near Orange

Showing the 50 nearest of 67 studies.
  1. Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

    NCT07037459

    • Phase 3
    • Ages 18 to 99 years
    • Sex: All

    Nearest sites: University of California Irvine (Orange, CA); National Institute of Clinical Research (Huntington Beach, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    8 sites within 50 mi
  2. Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

    NCT05082519

    • Phase 2
    • Ages 7 to 25 years
    • Sex: All

    Nearest sites: Children's Hospital Orange County (Orange, CA); Children's Hospital Los Angeles (Los Angeles, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  3. Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery

    NCT05975580

    • Phase 4
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: University of California Irvine Medical Center (Orange, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  4. Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)

    NCT06783751

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: University of California, Irvine (Orange, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  5. Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

    NCT07684235

    • Phase 3
    • Ages 18 to 99 years
    • Sex: All

    Nearest sites: Southern California Clinical Research (Santa Ana, CA); Ark Clinical Research- Tustin (Fountain Valley, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  6. Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

    NCT07752979

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Southern California Dermatology /ID# 282011 (Santa Ana, CA); University Clinical Investigators /ID# 282132 (Tustin, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  7. A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

    NCT07321886

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Southern California Clinical Research (Santa Ana, CA); University Clinical Investigators, Inc. (Tustin, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  8. A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

    NCT07392190

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Southern California Clinical Research (Santa Ana, CA); University Clinical Investigators, Inc. (Tustin, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  9. Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

    NCT07575399

    • Phase 3
    • Ages 18 to 99 years
    • Sex: All

    Nearest sites: Southern California Clinical Research (Santa Ana, CA); Peninsula Research Associates (Rolling Hills Estates, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  10. Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

    NCT07353931

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Wolverine Clinical Trials (Santa Ana, CA); Ark Clinical Research - Fountain Valley (Fountain Valley, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  11. A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

    NCT06897475

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Wolverine Clinical Trials (Santa Ana, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

    NCT07595549

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: University Clinical Investigators, Inc. (Tustin, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

    NCT06937086

    • Phase 3
    • Ages 18 to 70 years
    • Sex: All

    Nearest sites: Smart Cures Clinical Research (Anaheim, CA); United Medical Doctors - Los Alamitos (Los Alamitos, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  14. Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

    NCT06937099

    • Phase 3
    • Ages 18 to 70 years
    • Sex: All

    Nearest sites: Smart Cures Clinical Research (Anaheim, CA); United Medical Doctors - Los Alamitos (Los Alamitos, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  15. A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity

    NCT07291232

    • Phase 1
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: CenExel Act- Anaheim Clinical Trials /ID# 283200 (Anaheim, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

    NCT07720271

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Providence Medical Foundation (Fullerton, CA); Torrance Clinical Research Institute, Inc. (Lomita, CA)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  17. A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

    NCT06857942

    • Phase 4
    • Ages 18 years and older
    • Sex: All

    Nearest sites: First OC Dermatology Research Inc (Fountain Valley, CA); Metropolis Dermatology (Los Angeles, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  18. A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

    NCT07654374

    • Phase 3
    • Ages 18 to 79 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: ACCOMPLISH-2 Research Site (Fountain Valley, CA); ACCOMPLISH-2 Research Site (Rolling Hills Estates, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  19. A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

    NCT07351058

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: University of California Irvine (Irvine, CA); Orange County Research Center (Lake Forest, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  20. A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

    NCT07351045

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of California Irvine (Irvine, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes

    NCT06924320

    • Phase 1/2
    • Ages 18 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Altasciences Clinical Los Angeles, Inc. (Cypress, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)

    NCT07225816

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Altasciences Clinical LA, Inc. (Cypress, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity

    NCT07395687

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Altasciences Clinical LA, Inc. (Cypress, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body Weight

    NCT07710768

    • Phase 1
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Altasciences Clinical LA, Inc. (Cypress, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

    NCT07567001

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: California Heart Specialist (Huntington Beach, CA); Pacific Clinical Studies (Los Alamitos, CA)

    Distance to nearest recruiting site
    ~12 mi (city-level)
    Recruiting sites
    13 sites within 50 mi
  26. A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

    NCT07282600

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Pacific Clinical Studies (Los Alamitos, CA); Ark Clinical Research (Long Beach, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  27. A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

    NCT07369011

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Collaborative Neuroscience Research, LLC (Los Alamitos, CA); Ark Clinical Research (Long Beach, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  28. Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

    NCT07684144

    • Phase 3
    • Ages 18 to 99 years
    • Sex: All

    Nearest sites: Core Healthcare Group (Cerritos, CA); Empire Clinical Research (Pomona, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  29. A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

    NCT07794579

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Orange County Research Center (Lake Forest, CA); Healthy Brain Clinic (Long Beach, CA)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  30. Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

    NCT07037433

    • Phase 3
    • Ages 45 to 99 years
    • Sex: All

    Nearest sites: Orange County Research Center (Lake Forest, CA); Valley Clinical Trials, LLC dba Flourish Research (Covina, CA)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  31. A Study to Learn How Different Amounts of the Study Medicine Called PF-08642534 Are Tolerated and Act in the Body of People Who Have Obesity

    NCT07731139

    • Phase 1
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: Orange County Research Center (Lake Forest, CA)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671

    NCT07815678

    • Phase 1/2
    • Ages 25 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Research Site (Lake Forest, CA)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. A Phase 1 Study of VK2735 in Obese Adults Without Comorbidities

    NCT07838740

    • Phase 1
    • Ages 18 to 60 years
    • Sex: All

    Nearest site: Viking Clinical Site #001 (Lake Forest, CA)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. A Phase 1 Study of VK3019 in Overweight and Obese Adults Without Comorbidities

    NCT07846033

    • Phase 1
    • Ages 18 to 60 years
    • Sex: All

    Nearest site: Viking Clinical Site #001 (Lake Forest, CA)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

    NCT07668414

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Western University of Health Sciences (Pomona, CA)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

    NCT07783802

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Thrive Clinical Research Group (Glendora, CA)

    Distance to nearest recruiting site
    ~24 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

    NCT06143956

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Velocity Clinical Research, Huntington Park (Huntington Park, CA); Peninsula Research Associates (Rolling Hills Estates, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  38. A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

    NCT07589608

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Velocity Clinical Research, Huntington Park (Huntington Park, CA); Peninsula Research Associates (Rolling Hills Estates, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  39. Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

    NCT07770841

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: National Research Institute - Huntington Park (Huntington Park, CA); Los Angeles Institute for Metabolic Research (Los Angeles, CA)

    Distance to nearest recruiting site
    ~25 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  40. AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

    NCT07533175

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Torrance Clinical Research Institute, Inc. (Lomita, CA)

    Distance to nearest recruiting site
    ~27 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Use a Breathing Machine (PAP) (VESPER-OSA 1)

    NCT07823608

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Probe Clinical Research Corporation (Riverside, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

    NCT04453072

    • Interventional
    • Ages 13 to 30 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: UCLA / Jonsson Comprehensive Cancer Center (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients

    NCT04997473

    • Interventional
    • Ages 13 to 30 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: UCLA Mattel Children's Hospital (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. Brown Adipose Tissue Activity in Response to Semaglutide Administered to Obese Subjects.

    NCT05419726

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: UCLA Health (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. BrainWeighve App Feasibility Study

    NCT05530538

    • Interventional
    • Ages 14 to 21 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: UCLA Marion Davies Children's Center (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. Family Intervention to Prevent Childhood Obesity

    NCT05606731

    • Interventional
    • Ages 2 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Head Start (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects

    NCT05653258

    • Phase 2/3
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Cedars Sinai Medical Center (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. Use of Continuous Glucose Monitors in Children and Adolescents With Obesity

    NCT06254768

    • Interventional
    • Ages 10 to 21 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Pediatric Endocrinology Division, University of California (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. eMOTION: Examining Affective Mechanisms in Physical Activity Engagement

    NCT06570642

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: University of Southern California (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  50. FEAST Perinatal Support Program Intervention

    NCT06715787

    • Interventional
    • Ages 18 years and older
    • Sex: Female

    Nearest site: University of Southern California (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining an Obesity clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.