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Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

NCT07353931

This study is recruiting at 38 US sites in 19 states, according to its ClinicalTrials.gov record last updated .

Summary

The YDAN master protocol will support two independent studies, J3R-MC-YOA1 and J3R-MC-YOA2. Each study will investigate how well and safely Eloralintide (LY3841136) works in adults with obesity or overweight who have osteoarthritis (OA) of the knee with pain. Participation in the study will last about 75 weeks, including screening.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Osteoarthritis
  • Overweight or Obesity

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Eli Lilly and Company
Last updated on ClinicalTrials.gov
October 8, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Alabama · 1

  • AMR Clinical · Mobile, AL

Arizona · 4

  • Care Access - 801 South Power Road, Mesa · Mesa, AZ
  • Elite Pain and Spine Institute - South Crimson Road · Mesa, AZ
  • Elite Clinical Studies, LLC · Phoenix, AZ
  • Tucson Orthopaedic Institute - North Wyatt Drive · Tucson, AZ

California · 4

  • Ark Clinical Research - Fountain Valley · Fountain Valley, CA
  • Wolverine Clinical Trials · Santa Ana, CA
  • Encompass Clinical Research · Spring Valley, CA
  • Diablo Clinical Research, Inc. · Walnut Creek, CA

Colorado · 1

  • Skylight Health Research - Colorado Springs · Colorado Springs, CO

Florida · 3

  • Westside Center for Clinical Research · Jacksonville, FL
  • Care Access - St. Petersburg · St. Petersburg, FL
  • Conquest Research · Winter Park, FL

Georgia · 1

  • Orita Clinical Research · Decatur, GA

Idaho · 1

  • Medical Research Partners · Ammon, ID

Illinois · 1

  • Great Lakes Clinical Trials - Ravenswood · Chicago, IL

Indiana · 1

  • Qualmedica Research, LLC · Evansville, IN

Kansas · 1

  • AMR Clinical · Newton, KS

Kentucky · 1

  • Monroe Biomedical Research - Louisville · Louisville, KY

Massachusetts · 2

  • Skylight Health Research - Burlington · Burlington, MA
  • Care Access - Quincy · Quincy, MA

New York · 4

  • Ellipsis Research Group - Brooklyn - 7th Street · Brooklyn, NY
  • Rochester Clinical Research - Buffalo · Buffalo, NY
  • NYC Research INC · Long Island City, NY
  • Rochester Clinical Research, LLC · Rochester, NY

Oklahoma · 1

  • Central States Research · Tulsa, OK

Pennsylvania · 1

  • Keystone Clinical Studies · Plymouth Meeting, PA

Texas · 8

  • JCCT - Juno Bellaire Site · Bellaire, TX
  • Epic Medical Research - DeSoto · DeSoto, TX
  • Valley Institute of Research - Fort Worth · Fort Worth, TX
  • Care Access - Houston · Houston, TX
  • Endeavor Clinical Trials · San Antonio, TX
  • VIP Trials · San Antonio, TX
  • Consano Clinical Research, LLC · Shavano Park, TX
  • Texas Valley Clinical Research · Weslaco, TX

Utah · 1

  • AMR Clinical · South Jordan, UT

Virginia · 1

  • Charlottesville Medical Research · Charlottesville, VA

Washington · 1

  • Paramount Clinical Research - Data Point Clinical Research · Kirkland, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.