A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
NCT07783802
This study is recruiting at 29 US sites in 17 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to measure the change in high-sensitivity C-reactive protein (hsCRP), a marker of inflammation in the body, with clazakizumab compared with placebo in adults who have elevated hsCRP and at increased risk for cardiovascular event. Participation in the study will last about 9 months.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Atherosclerosis
- Cardiovascular Disease
- Obesity
- Hypertension
- Diabetes Mellitus, Type 2
- Renal Insufficiency, Chronic
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Eli Lilly and Company
- Last updated on ClinicalTrials.gov
- October 8, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- Heart Center Research, LLC · Huntsville, AL
Arizona · 2
- Eclipse Clinical Research · Tucson, AZ
- Pima Heart · Tucson, AZ
California · 1
- Thrive Clinical Research Group · Glendora, CA
Florida · 4
- Omega Research Orlando · Altamonte Springs, FL
- American Research Institute · Cutler Bay, FL
- K2 Medical Research - Maitland · Maitland, FL
- Florida Institute For Clinical Research, LLC · Orlando, FL
Georgia · 1
- North Georgia Clinical Research · Woodstock, GA
Indiana · 1
- Franciscan Physician Network - Indiana Heart Physicians · Indianapolis, IN
Massachusetts · 1
- K2 Medical Research - Foxborough · Foxborough, MA
Michigan · 1
- Revival Research Institute, LLC · Dearborn, MI
Mississippi · 1
- Olive Branch Family Medical Center · Olive Branch, MS
Nevada · 2
- Excel Clinical Research, LLC · Las Vegas, NV
- Palm Research Center Tenaya · Las Vegas, NV
New York · 2
- Rochester Clinical Research - Buffalo · Buffalo, NY
- CHEAR Center LLC · The Bronx, NY
Ohio · 1
- Velocity Clinical Research, Cincinnati, Springdale · Cincinnati, OH
Pennsylvania · 2
- Suburban Research Associates · West Chester, PA
- Cardiology Consultants of Philadelphia Yardley · Yardley, PA
South Carolina · 1
- Monroe Biomedical Research - Charleston · North Charleston, SC
Texas · 5
- Horizon Clinical Research Group · Cypress, TX
- Cardiovascular Specialists of Willowbrook · Houston, TX
- Texas Cardiology Associates of Houston · Kingwood, TX
- Revival Research Institute, LLC · McKinney, TX
- Texas Institute of Cardiology, PA · McKinney, TX
Utah · 1
- Ogden Clinic - Canyon View · Ogden, UT
Virginia · 2
- Carient Heart & Vascular - Manassas · Manassas, VA
- Carient Heart and Vascular LLC-Reston · Reston, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.