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A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

NCT07595549

This study is recruiting at 30 US sites in 13 states, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this clinical study is to learn about the effects and safety of berobenatide (PF-08653944). This may help people with overweight or obesity lose weight. People in this study may also have type 2 diabetes. About 950 adults will be in this study. Berobenatide will be compared to a placebo. A placebo does not have any medicine in it but looks just like the medicine being studied. Berobenatide or placebo is given by a shot under the skin in the belly area.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Obesity
  • Overweight and/or Obesity
  • Overweight

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Pfizer
Last updated on ClinicalTrials.gov
October 13, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 7

  • San Fernando Valley Health Institute · Canoga Park, CA
  • Headlands Research California, LLC · Escondido, CA
  • ImmuniMet, LLC · Modesto, CA
  • Clinical Trials Research · Sacramento, CA
  • University Clinical Investigators, Inc. · Tustin, CA
  • Diablo Clinical Research, Inc. · Walnut Creek, CA
  • Southern California Retina Specialists · West Hills, CA

Florida · 4

  • Nature Coast Clinical Research · Crystal River, FL
  • West Coast Eye Institute · Lecanto, FL
  • South Broward Research · Miramar, FL
  • Center for Diabetes, Obesity and Metabolism Inc · Pembroke Pines, FL

Illinois · 4

  • Cedar Crosse Research Center · Chicago, IL
  • Northwestern University · Chicago, IL
  • Endeavor Health - Family Medicine Administration · Evanston, IL
  • Endeavor Health- Endocrinology Research · Skokie, IL

Indiana · 1

  • MediSphere Medical Research Center, LLC · Evansville, IN

Maryland · 1

  • Ascension Saint Agnes Heart Care · Baltimore, MD

Michigan · 1

  • Aa Mrc Llc · Flint, MI

Nebraska · 1

  • University Of Nebraska Medical Center · Omaha, NE

New Mexico · 1

  • Albuquerque Clinical Trials, Inc. · Albuquerque, NM

New York · 1

  • Weill Cornell Medicine - Comprehensive Weight Control Center · New York, NY

North Carolina · 3

  • Medication Management, LLC · Greensboro, NC
  • Accellacare - Wilmington · Wilmington, NC
  • Jeffrey Coleman, OD · Wilmington, NC

Ohio · 2

  • Midwest Eye Center · Cincinnati, OH
  • Velocity Clinical Research, Mt. Auburn · Cincinnati, OH

Texas · 3

  • PlanIt Research, LLC · Houston, TX
  • PlanIt Research, LLC (Monitoring Room) · Houston, TX
  • VIP Trials · San Antonio, TX

Virginia · 1

  • York Clinical Research, LLC · Norfolk, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.