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Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

NCT05082519

This study is recruiting at 15 US sites in 12 states, according to its ClinicalTrials.gov record last updated .

Summary

This study is for older children, adolescents, and young adults with B-cell Acute Lymphoblastic Leukemia (B-ALL). Higher amounts of body fat is associated with resistance to chemotherapy in patients with B-ALL. Chemotherapy during the first month causes large gains in body fat in most people, even those who start chemotherapy at a healthy weight.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • B-cell Acute Lymphoblastic Leukemia
  • Obesity

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
7 to 25 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Etan Orgel
Last updated on ClinicalTrials.gov
August 19, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 3

  • Children's Hospital Los Angeles · Los Angeles, CA
  • Children's Hospital Orange County · Orange, CA
  • UCSF School of Medicine · San Francisco, CA

Colorado · 1

  • Colorado Children's Hospital · Denver, CO

Illinois · 1

  • Ann & Robert H. Lurie Children's Hospital of Chicago · Chicago, IL

Kansas · 1

  • Children's Mercy Hospital · Kansas City, KS

Michigan · 1

  • C.S. Mott University of Michigan · Ann Arbor, MI

Minnesota · 1

  • Children's Hospitals and Clinics of Minnesota · Minneapolis, MN

North Carolina · 1

  • Levine Children's Hospital · Charlotte, NC

Ohio · 1

  • Cincinnati Children's Hospital Medical Center · Cincinnati, OH

Oregon · 1

  • Oregon Health & Science University · Portland, OR

Pennsylvania · 1

  • Children's Hospital of Philadelphia · Philadelphia, PA

Texas · 2

  • University of Texas, Southwestern · Dallas, TX
  • Baylor Texas Children's Hospital · Houston, TX

Utah · 1

  • Primary Children's Hospital · Salt Lake City, UT

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.