A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
NCT07794579
This study is recruiting at 69 US sites in 29 states, according to its ClinicalTrials.gov record last updated .
Summary
This study will evaluate the efficacy and safety of orforglipron in participants with overweight and assess whether it helps reduce the future risk of obesity-related conditions, including type 2 diabetes, hypertension, and dyslipidemia, and progression to class 1 obesity.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Overweight
- Prediabetic State
- Prehypertension
- Obesity, Abdominal
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Eli Lilly and Company
- Last updated on ClinicalTrials.gov
- October 8, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 3
- Pinnacle Research Group, LLC · Anniston, AL
- Central Research Associates · Birmingham, AL
- Cahaba Research - Pelham · Pelham, AL
Arizona · 2
- Care Access - 801 South Power Road, Mesa · Mesa, AZ
- Synexus Clinical Research US, Inc./Orange Grove Family Practice · Tucson, AZ
California · 9
- Orange County Research Center · Lake Forest, CA
- Healthy Brain Clinic · Long Beach, CA
- Los Angeles Institute for Metabolic Research · Los Angeles, CA
- Desert Oasis Healthcare Medical Group · Palm Springs, CA
- Artemis Institute for Clinical Research · Riverside, CA
- Riverside Clinical · Riverside, CA
- Headlands Research- Sacramento · Sacramento, CA
- Norcal Endocrinology & Internal Medicine · San Ramon, CA
- Diablo Clinical Research, Inc. · Walnut Creek, CA
Connecticut · 1
- Chase Medical Research, LLC · Waterbury, CT
Florida · 8
- Excel Medical Clinical Trials · Boca Raton, FL
- Flourish Research Acquisition, LLC dba Flourish Research - North Miami · Miami, FL
- New Age Medical Research Corporation · Miami, FL
- Renstar Medical Research · Ocala, FL
- Headlands Research Orlando · Orlando, FL
- Oviedo Medical Research · Oviedo, FL
- Care Access - St. Petersburg · St. Petersburg, FL
- Precision Clinical Research · Sunrise, FL
Georgia · 4
- SKY Clinical Research Network Group-Brown · Atlanta, GA
- HOPE Clinical Research & Wellness · Conyers, GA
- Care Access - Dalton Walmart · Dalton, GA
- Care Access - Decatur · Decatur, GA
Idaho · 2
- Family First Medical Center · Idaho Falls, ID
- Solaris Clinical Research · Meridian, ID
Illinois · 1
- Great Lakes Clinical Trials - Ravenswood · Chicago, IL
Iowa · 1
- Iowa Diabetes and Endocrinology Research Center · West Des Moines, IA
Louisiana · 2
- Pennington Biomedical Research Center · Baton Rouge, LA
- IMA Clinical Research Monroe-Main · Monroe, LA
Maryland · 1
- Centennial Medical Group · Columbia, MD
Massachusetts · 1
- Brigham and Women's Hospital Diabetes Program · Boston, MA
Michigan · 2
- Great Lakes Research Group, Inc. · Bay City, MI
- Great Lakes Research Institute · Southfield, MI
Minnesota · 1
- Headlands Research-Twin Cities · Maplewood, MN
Missouri · 1
- Clinvest Headlands Llc · Springfield, MO
Nevada · 2
- M3 Wake Research - Las Vegas Cimarron · Las Vegas, NV
- Renascor Clinical Research · Reno, NV
New Jersey · 1
- IMA Clinical Research Warren · Warren Township, NJ
New York · 2
- Drug Trials America · Hartsdale, NY
- Rochester Clinical Research, LLC · Rochester, NY
North Carolina · 3
- Medication Management · Greensboro, NC
- West Clinical Research · Morehead City, NC
- Trial Management Associates - Wilmington - Floral Parkway · Wilmington, NC
North Dakota · 1
- Lillestol Research · Fargo, ND
Ohio · 1
- Remington-Davis, Inc · Columbus, OH
Oklahoma · 1
- Central States Research · Tulsa, OK
Oregon · 1
- The Corvallis Clinic, P.C. · Corvallis, OR
Pennsylvania · 2
- Clinical Renal Associates Ltd. · Media, PA
- Suburban Research Associates · West Chester, PA
South Carolina · 1
- Care Access - Mauldin · Mauldin, SC
Tennessee · 2
- New Phase Research and Development · Knoxville, TN
- Clinical Research Associates Inc · Nashville, TN
Texas · 11
- IMA Clinical Research Austin · Austin, TX
- Headlands Horizons, LLC dba Headlands Research-Brownsville · Brownsville, TX
- Cedar Health Research - Texas Native Health · Dallas, TX
- Headlands Research-El Paso · El Paso, TX
- Cedar Health Research - Euless · Euless, TX
- Biopharma Informatic, LLC · Houston, TX
- Care Access - Houston - Clinical Trials Center by Walmart & Care Access · Houston, TX
- DCOL Center for Clinical Research · Longview, TX
- IMA Clinical Research San Antonio · San Antonio, TX
- Consano Clinical Research, LLC · Shavano Park, TX
- Care Access - Tyler - Clinical Trials Center by Walmart & Care Access · Tyler, TX
Virginia · 1
- Clinical Research Partners, LLC · Richmond, VA
West Virginia · 1
- Frontier Clinical Research, LLC · Kingwood, WV
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.