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A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

NCT06897475

This study is recruiting at 25 US sites in 14 states, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this study is to measure the change in hemoglobin A1c (HbA1c) with LY3457263 compared with placebo in participants with type 2 diabetes who are not at HbA1c goal when treated with a stable dose of semaglutide or tirzepatide. Participation in the study will last about 9 months.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Type 2 Diabetes

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 to 75 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Eli Lilly and Company
Last updated on ClinicalTrials.gov
October 9, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 1

  • Helios Clinical Research - Phoenix · Phoenix, AZ

California · 1

  • Wolverine Clinical Trials · Santa Ana, CA

Florida · 2

  • Renstar Medical Research · Ocala, FL
  • Oviedo Medical Research · Oviedo, FL

Georgia · 4

  • Balanced Life Health Care Solutions/SKYCRNG · Lawrenceville, GA
  • Physicians Research Associates · Lawrenceville, GA
  • Rophe Adult and Pediatric Medicine/SKYCRNG · Union City, GA
  • North Georgia Clinical Research · Woodstock, GA

Idaho · 1

  • Elite Clinical Trials · Rexburg, ID

Indiana · 1

  • Investigators Research Group · Brownsburg, IN

New Jersey · 1

  • Clinical Research of Philadelphia · Pennington, NJ

New York · 3

  • NYC Research INC · Long Island City, NY
  • Richmond University Medical Center · Staten Island, NY
  • Southgate Medical Group · West Seneca, NY

North Carolina · 2

  • Lucas Research, Inc. · Morehead City, NC
  • Shelby Clinical Research · Shelby, NC

Ohio · 1

  • Providence Health Partners-Center for Clinical Research · Dayton, OH

Oklahoma · 1

  • Alliance for Multispecialty Research, LLC · Norman, OK

Pennsylvania · 1

  • Frontier Clinical Research, LLC · Scottdale, PA

Texas · 5

  • Juno Research · Houston, TX
  • Southern Endocrinology Associates · Mesquite, TX
  • Texas Diabetes & Endocrinology, P.A. · Round Rock, TX
  • Consano Clinical Research, LLC · Shavano Park, TX
  • Texas Valley Clinical Research · Weslaco, TX

Washington · 1

  • Eastside Research Associates · Redmond, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.