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A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

NCT06143956

This study is recruiting at 43 US sites in 21 states, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this Phase-2 chronic weight management master protocol (CWMM) is to create a framework to evaluate the safety and efficacy of various investigational interventions for chronic weight management with intervention-specific appendices (ISAs). The CWMM establishes entry criteria for newly enrolled participants across the master and the ISAs. The ISAs may start independently of other ISAs as interventions become available for clinical testing. The results for the CWMM screening record will be reported when all the ISA's complete.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Obesity
  • Overweight

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 to 75 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Eli Lilly and Company
Last updated on ClinicalTrials.gov
October 7, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 3

  • The Institute for Liver Health II dba Arizona Clinical Trials - Mesa · Chandler, AZ
  • Headlands Research - Scottsdale · Scottsdale, AZ
  • The Institute for Liver Health II dba Arizona Liver Health-Tucson · Tucson, AZ

California · 4

  • NorCal Medical Research, Inc · Greenbrae, CA
  • Velocity Clinical Research, Huntington Park · Huntington Park, CA
  • Peninsula Research Associates · Rolling Hills Estates, CA
  • Diablo Clinical Research, Inc. · Walnut Creek, CA

Connecticut · 1

  • Stamford Therapeutics Consortium · Stamford, CT

Florida · 5

  • New Horizon Research Center · Miami, FL
  • Indago Research & Health Center, Inc · Miami Lakes, FL
  • Suncoast Clinical Research, Inc. · New Port Richey, FL
  • Charter Research - Winter Park · Orlando, FL
  • Charter Research - Lady Lake · The Villages, FL

Idaho · 1

  • Medical Research Partners · Ammon, ID

Illinois · 1

  • Great Lakes Clinical Trials - Ravenswood · Chicago, IL

Iowa · 1

  • Iowa Diabetes and Endocrinology Research Center · West Des Moines, IA

Kansas · 1

  • Cotton O'Neil Diabetes & Endocrinology · Topeka, KS

Kentucky · 1

  • Monroe Biomedical Research - Louisville · Louisville, KY

Massachusetts · 2

  • Knownwell · Needham, MA
  • Lucida Clinical Trials · New Bedford, MA

Michigan · 2

  • Headlands Research - Detroit · Southfield, MI
  • Arcturus Healthcare , PLC, Troy Internal Medicine Research Division · Troy, MI

Missouri · 2

  • StudyMetrix Research · City of Saint Peters, MO
  • Clinvest Headlands Llc · Springfield, MO

Nevada · 1

  • Las Vegas Medical Research · Las Vegas, NV

New York · 3

  • Dent Neurologic Institute · Amherst, NY
  • Velocity Clinical Research, Syracuse · East Syracuse, NY
  • Rochester Clinical Research, LLC · Rochester, NY

North Carolina · 4

  • Medication Management · Greensboro, NC
  • Monroe Biomedical Research · Monroe, NC
  • Lucas Research, Inc · Morehead City, NC
  • Lucas Research, Inc. · New Bern, NC

Ohio · 1

  • CTI Clinical Research Center · Cincinnati, OH

South Carolina · 1

  • Tribe Clinical Research, LLC · Greenville, SC

Tennessee · 1

  • Quality Medical Research · Nashville, TN

Texas · 6

  • IMA Clinical Research Austin · Austin, TX
  • FutureSearch Trials of Dallas · Dallas, TX
  • Velocity Clinical Research, Dallas · Dallas, TX
  • PlanIt Research, PLLC · Houston, TX
  • Endeavor Clinical Trials · San Antonio, TX
  • Texas Valley Clinical Research · Weslaco, TX

Virginia · 1

  • Sovah Clinical Research-River District · Danville, VA

Washington · 1

  • Central Washington Health Services Association d/b/a Confluence Health · Wenatchee, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.