Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
NCT06937099
This study is recruiting at 35 US sites in 22 states, according to its ClinicalTrials.gov record last updated .
Summary
The main purpose of this study is to evaluate the efficacy and safety of mirikizumab and placebo compared with mirikizumab and concomitantly administered tirzepatide in adult participants with moderately to severely active CD and obesity, or overweight. The maximum duration of this study is up to 61 weeks.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Crohn's Disease
- Obesity or Overweight
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Eli Lilly and Company
- Last updated on ClinicalTrials.gov
- October 7, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- Digestive Health Specialists · Dothan, AL
California · 4
- Smart Cures Clinical Research · Anaheim, CA
- Cedars-Sinai Medical Center · Beverly Hills, CA
- United Medical Doctors - Los Alamitos · Los Alamitos, CA
- California Medical Research Associates · Northridge, CA
Florida · 6
- Gastro Health Research - Miami · Miami, FL
- Research Associates of South Florida - Miami - Southwest 8th Street · Miami, FL
- Digestive and Liver Center of Florida · Orlando, FL
- Orlando Health · Orlando, FL
- Gastro Health Research - Pensacola · Pensacola, FL
- Precision Clinical Research · Sunrise, FL
Idaho · 1
- Grand Teton Research Group · Idaho Falls, ID
Illinois · 1
- Rush University Medical Center · Chicago, IL
Indiana · 2
- Indiana University Health University Hospital · Indianapolis, IN
- Gastroenterology Health Partners · New Albany, IN
Kentucky · 1
- Gastroenterology Health Partners · Louisville, KY
Louisiana · 2
- Care Access - New Iberia · New Iberia, LA
- Louisiana Research Center · Shreveport, LA
Maryland · 1
- Capital Digestive Care - Chevy Chase · Chevy Chase, MD
Massachusetts · 1
- Lucida Clinical Trials · New Bedford, MA
Missouri · 1
- Washington University School of Medicine · St Louis, MO
New Hampshire · 1
- Dartmouth-Hitchcock Medical Center · Lebanon, NH
New York · 2
- New York Gastroenterology Associates · New York, NY
- Care Access - Yonkers · Yonkers, NY
North Carolina · 1
- Coastal Research Institute - Fayetteville · Fayetteville, NC
Ohio · 1
- Gastro Intestinal Research Institute of Northern Ohio, LLC · Westlake, OH
Pennsylvania · 1
- Thomas Jefferson University - Medicine/GI and Hepatology · Philadelphia, PA
Rhode Island · 1
- University Gastroenterology · Providence, RI
South Carolina · 1
- Gastroenterology Associates - Patewood · Greenville, SC
Tennessee · 1
- Gastroenterology Center Of The Midsouth · Cordova, TN
Texas · 3
- Gastroenterology Research of San Antonio · San Antonio, TX
- Southern Star Research Institute · San Antonio, TX
- Tyler Research Institute · Tyler, TX
Washington · 1
- Washington Gastroenterology - Tacoma · Tacoma, WA
Wisconsin · 1
- Wisconsin Center for Advanced Research · Milwaukee, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.