Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities
NCT07752979
This study is recruiting at 55 US sites in 18 states, according to its ClinicalTrials.gov record last updated .
Summary
Obesity is a condition where a person has excessive body fat, defined by a body mass index (BMI) of 30 kg/m2 or higher. The goal of this study is to evaluate the effect of various doses of ABBV-295 compared to placebo on reducing body weight at Week 32 in participants with obesity or overweight with weight-related comorbidities. ABBV-295 is an investigational long-acting amylin analog being developed for chronic weight management. Participants are placed into multiple treatment groups with different dosing paradigms of ABBV-295 or placebo.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Obesity
- Overweight
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- AbbVie
- Last updated on ClinicalTrials.gov
- October 14, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- Cahaba Research - Pelham /ID# 282381 · Pelham, AL
Arizona · 1
- Headlands Research - Scottsdale /ID# 282571 · Scottsdale, AZ
California · 9
- John Muir Health - Concord /ID# 282469 · Concord, CA
- NorCal Medical Research /ID# 283117 · Greenbrae, CA
- Velocity Clinical Research - Huntington Park /ID# 282987 · Huntington Park, CA
- Los Angeles Institute for Metabolic Research /ID# 282059 · Los Angeles, CA
- Peninsula Research Associates /ID# 282158 · Rolling Hills Estates, CA
- Southern California Dermatology /ID# 282011 · Santa Ana, CA
- Encompass Clinical Research /ID# 282483 · Spring Valley, CA
- University Clinical Investigators /ID# 282132 · Tustin, CA
- Diablo Clinical Research /ID# 282530 · Walnut Creek, CA
Florida · 13
- Innovative Research of West Florida /ID# 281963 · Clearwater, FL
- Northeast Research Institute (NERI) /ID# 282015 · Fleming Island, FL
- Encore Research Group-Jacksonville Center for Clinical Research /ID# 282740 · Jacksonville, FL
- Altus Clinical Research - Lake Worth - South Congress Avenue /ID# 281979 · Lake Worth, FL
- South Florida Wellness & Clinic /ID# 282022 · Margate, FL
- South Broward Research /ID# 282125 · Miramar, FL
- Suncoast Clinical Research Pasco County /ID# 282412 · New Port Richey, FL
- Charter Research - Winter Park /ID# 281968 · Orlando, FL
- Florida Institute For Clinical Research /ID# 282739 · Orlando, FL
- Progressive Medical Research /ID# 282838 · Port Orange, FL
- Charter Research - The Villages /ID# 282376 · The Villages, FL
- Metabolic Research Institute /ID# 282350 · West Palm Beach, FL
- Encore Medical Research - Weston /ID# 282044 · Weston, FL
Idaho · 1
- Elite Clinical Trials - Blackfoot /ID# 282042 · Blackfoot, ID
Illinois · 1
- Great Lakes Clinical Trials - West Wilson Avenue /ID# 282378 · Chicago, IL
Kentucky · 1
- L-MARC Research Center /ID# 282008 · Louisville, KY
Mississippi · 1
- Prime Health and Wellness /ID# 282254 · Fayette, MS
Missouri · 1
- Studymetrix Research /ID# 282163 · City of Saint Peters, MO
Montana · 1
- Mercury Street Medical /ID# 282016 · Butte, MT
Nevada · 1
- Vector Clinical Trials /ID# 282265 · Las Vegas, NV
New York · 1
- Rochester Clinical Research /ID# 282484 · Rochester, NY
North Carolina · 5
- Medication Management /ID# 281965 · Greensboro, NC
- Monroe Biomedical Research /ID# 282009 · Monroe, NC
- Centricity Research - Morehead city /ID# 283264 · Morehead City, NC
- Lucas Research - New Bern /ID# 282747 · New Bern, NC
- Accellacare - Tradd Court - Wilmington /ID# 282200 · Wilmington, NC
North Dakota · 1
- Lillestol Research LLC /ID# 281978 · Fargo, ND
Ohio · 1
- CTI Clinical Research Center /ID# 282043 · Cincinnati, OH
Tennessee · 4
- Holston Medical Group - Bristol /ID# 282045 · Bristol, TN
- New Phase Research & Development /ID# 282131 · Knoxville, TN
- Summit Medical Group- Halls Family Physicians /ID# 282435 · Knoxville, TN
- Clinical Research Associates - Nashville /ID# 282161 · Nashville, TN
Texas · 8
- Amarillo Medical Specialists /ID# 282380 · Amarillo, TX
- Elligo Clinical Research Center /ID# 282166 · Austin, TX
- JCCT - Juno Bellaire /ID# 282263 · Bellaire, TX
- Velocity Clinical Research - Dallas /ID# 282734 · Dallas, TX
- Juno Research /ID# 282413 · Houston, TX
- PlanIt Research /ID# 282204 · Houston, TX
- Dcol Center For Clinical Research /ID# 281961 · Longview, TX
- Texas Diabetes and Endocrinology /ID# 282291 · Round Rock, TX
Virginia · 4
- Washington Center For Weight Management And Research /ID# 282047 · Arlington, VA
- Sovah Health - Danville /ID# 282876 · Danville, VA
- Health Research Of Hampton Roads /ID# 282014 · Newport News, VA
- National Clinical Research /ID# 282007 · Richmond, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.