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Lung Cancer Clinical Trials near St Louis, MO

108 studies for Lung Cancer are recruiting at 238 sites within 50 miles of St Louis, Missouri, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Lung Cancer trials in the US or all trials near St Louis.

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Recruiting now

Lung Cancer studies enrolling near St Louis

Showing the 50 nearest of 108 studies.
  1. Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

    NCT03851445

    • Phase 2/3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    18 sites within 50 mi
  2. Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

    NCT04267848

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    14 sites within 50 mi
  3. Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

    NCT06616584

    • Phase 2/3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital South (St Louis, MO); Missouri Baptist Medical Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    12 sites within 50 mi
  4. Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

    NCT05334069

    • Observational
    • Ages 40 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    11 sites within 50 mi
  5. Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

    NCT06418204

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    11 sites within 50 mi
  6. Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

    NCT03191149

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    10 sites within 50 mi
  7. Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

    NCT06031688

    • Phase 2
    • Ages 18 Minutes and older
    • Sex: All

    Nearest sites: Mercy Hospital South (St Louis, MO); Siteman Cancer Center at Christian Hospital (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    8 sites within 50 mi
  8. Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

    NCT06500481

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital South (St Louis, MO); Siteman Cancer Center at Christian Hospital (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    8 sites within 50 mi
  9. Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

    NCT06686771

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Siteman Cancer Center at Christian Hospital (St Louis, MO); Siteman Cancer Center-South County (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    8 sites within 50 mi
  10. Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

    NCT05624996

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  11. LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

    NCT06073431

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital South (St Louis, MO); Missouri Baptist Medical Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  12. Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

    NCT04181060

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  13. Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

    NCT05642572

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  14. Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

    NCT06116682

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital South (St Louis, MO); Missouri Baptist Medical Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  15. A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

    NCT07293247

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Missouri Baptist Medical Center (St Louis, MO); Cancer Care Center of O'Fallon (O'Fallon, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  16. Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

    NCT06096844

    • Phase 3
    • Ages 70 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  17. Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

    NCT06498635

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  18. GEMINI-NSCLC: NSCLC Biomarker Study

    NCT05236114

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Clinic Oncology and Hematology - David C. Pratt Cancer Center (St Louis, MO); Mercy Clinic Oncology and Hematology - Sindelar Cancer Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  19. A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

    NCT06312137

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Research - David C. Pratt Cancer Center ( Site 0006) (St Louis, MO); Mercy South - David M Sindelar Cancer Center ( Site 0098) (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  20. Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

    NCT06767514

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Clinical Study Site (St Louis, MO); Clinical Study Site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  21. Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

    NCT06769126

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  22. CARE Tool Study Aim 3

    NCT07296887

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Washington University School of Medicine (St Louis, MO); Alton Memorial Hospital (Alton, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  23. Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

    NCT07327489

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital - South (St Louis, MO); Mercy Hospital -STL (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  24. A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

    NCT03093116

    • Phase 1/2
    • Ages 12 years and older
    • Sex: All

    Nearest site: Washington University Infusion Center Pharmacy (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    NCT03452774

    • Observational
    • Ages Any age
    • Sex: All

    Nearest site: Massive Bio SYNERGY-AI site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

    NCT03526835

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine at St Louis (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

    NCT04302025

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Siteman Cancer Center - Washington University Medical Campus (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

    NCT04354064

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

    NCT04981119

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

    NCT05123482

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Research Site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

    NCT05267626

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Phase 2 Study for the Patient, Who Has Diagnosed With Small Cell Lung Cancer (SCLC) or Non Small Cell Lung Cancer (NSCLC) or Renal Cell Carcinoma (RCC) and Finished the First Line Stand Treatment , Need More Treatment

    NCT05363280

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Siteman Cancer Center, Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

    NCT05490472

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

    NCT05498428

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School Of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

    NCT05652686

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (Siteman Cancer Center) (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients

    NCT05703971

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine - Siteman Cancer Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

    NCT05786924

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

    NCT05856981

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University Medical Campus (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

    NCT06026410

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

    NCT06051695

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

    NCT06172478

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University, School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

    NCT06203210

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Mercy Clinic Oncology and Hematology Sindelar Cancer Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

    NCT06218914

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Research Site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

    NCT06236438

    • Phase 2/3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University-School of Medicine /ID# 262759 (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. A Phase 1/1b Study of IAM1363 in HER2 Cancers

    NCT06253871

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. A Study of KK2269 in Adult Participants With Solid Tumors

    NCT06266299

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

    NCT06270706

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

    NCT06350097

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Research Site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node or Other High Risk Features

    NCT06449313

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine-Sitemen Cancer Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  50. A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

    NCT06465069

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine in St. Louis (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Lung Cancer clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.