Lung Cancer Clinical Trials near Orange, CA
228 studies for Lung Cancer are recruiting at 533 sites within 50 miles of Orange, California, according to ClinicalTrials.gov data processed .
Distances are city-level approximations. See all Lung Cancer trials in the US or all trials near Orange.
Recruiting now
Lung Cancer studies enrolling near Orange
- A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
NCT06667076
- Phase 2
- Ages 18 years and older
- Sex: All
Nearest sites: St. Joseph Hospital Center for Cancer Prevention and Treatment (Orange, CA); University of California Irvine (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 18 sites within 50 mi
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+)
NCT07711691
- Interventional
- Ages 50 to 80 years
- Sex: All
Nearest sites: Primary Care & Internal Medicine Services (Orange, CA); UCI Chao Family Comprehensive Cancer Center (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 13 sites within 50 mi
- Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
NCT06767514
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Clinical Study Site (Orange, CA); Clinical Study Site (Anaheim, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 7 sites within 50 mi
- Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
NCT06350097
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Research Site (Orange, CA); Research Site (Los Alamitos, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 5 sites within 50 mi
- A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)
NCT06858813
- Phase 1
- Ages 18 years and older
- Sex: All
Nearest sites: University Of California Irvine Medical Center /ID# 270507 (Orange, CA); City of Hope - Orange County Lennar Foundation Cancer Center /ID# 276120 (Irvine, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 5 sites within 50 mi
- Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
NCT05983432
- Phase 1
- Ages 18 years and older
- Sex: All
Nearest sites: University of California Irvine Medical Center (Orange, CA); City of Hope Cancer Center (Duarte, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 4 sites within 50 mi
- A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
NCT06312137
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: St. Joseph Hospital-The Center for Cancer Prevention and Treatment ( Site 4002) (Orange, CA); Hoag Memorial Hospital Presbyterian ( Site 0096) (Newport Beach, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 4 sites within 50 mi
- A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
NCT06793215
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: University of California Irvine (Orange, CA); UCI Health-CIACC (Irvine, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 4 sites within 50 mi
- Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
NCT07195695
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: University of California Irvine (Orange, CA); OPN Healthcare, Inc. (Glendale, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 4 sites within 50 mi
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
NCT03452774
- Observational
- Ages Any age
- Sex: All
Nearest sites: Massive Bio SYNERGY-AI site (Orange, CA); Massive Bio SYNERGY-AI site (Irvine, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 3 sites within 50 mi
- Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
NCT06890598
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: University of California, Irvine (UCI) Health - UC Irvine Medical Center (Orange, CA); UCLA Hematology/Oncology - Santa Monica (Los Angeles, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 3 sites within 50 mi
- Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations
NCT07185997
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Providence St. Joseph Hospital (Orange, CA); St. Jude Medical Center (Fullerton, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 3 sites within 50 mi
- A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
NCT04302025
- Phase 2
- Ages 18 years and older
- Sex: All
Nearest sites: The Center for Cancer Prevention and Treatment at St.Joseph Hospital of Orange (Orange, CA); University of California Los Angeles - Jonsson Comprehensive Cancer Center (Los Angeles, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
NCT05208762
- Phase 1
- Ages 18 years and older
- Sex: All
Nearest sites: UC Irvine Health - Chao Family Comprehensive Cancer Center (Orange, CA); Chao Family Comprehensive Cancer Center and Ambulatory Care (Irvine, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
NCT05379985
- Phase 1/2
- Ages 18 years and older
- Sex: All
Nearest sites: UC Irvine/Chao Family Comprehensive Cancer Center (Orange, CA); UCLA (Santa Monica, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- A Study of VET3-TGI in Patients With Solid Tumors
NCT06444815
- Phase 1
- Ages 18 years and older
- Sex: All
Nearest sites: UC Irvine Health (Orange, CA); USC/Norris Comprehensive Cancer Center (Los Angeles, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
NCT06765109
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: University of California, Irvine Health (Orange, CA); Hoag Hospital Newport Beach (Newport Beach, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
NCT07100080
- Phase 2/3
- Ages 18 years and older
- Sex: All
Nearest sites: University of California, Irvine (UCI) Health - UC Irvine Medical Center (Orange, CA); UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care building (Irvine, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)
NCT07140016
- Phase 1
- Ages 18 years and older
- Sex: All
Nearest sites: University of California - Irvine (Orange, CA); Providence Medical Foundation - Fullerton - Virginia K. Crosson Cancer Center (Fullerton, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)
NCT07154706
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: UCI Chao Family Comprehensive Cancer Center (Orange, CA); UCLA (Los Angeles, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors
NCT07284186
- Phase 1
- Ages 18 years and older
- Sex: All
Nearest sites: Research Site (Orange, CA); Research Site (Duarte, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.
NCT07365319
- Phase 2/3
- Ages 18 years and older
- Sex: All
Nearest sites: Providence St. Joseph Hospital (Orange, CA); Los Angeles Cancer Network (Glendale, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- Patient-Derived Xenografts to Reduce Cancer Health Disparities
NCT04410302
- Observational
- Ages 21 to 100 years
- Sex: All
Nearest site: UC Irvine Health/Chao Family Comprehensive Cancer Center (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC
NCT04686305
- Phase 1
- Ages 18 years and older
- Sex: All
Nearest site: Research Site (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- TATE and Pembrolizumab (MK3475) in mCRC and NSCLC
NCT04701476
- Phase 2
- Ages 18 years and older
- Sex: All
Nearest site: University of California, Irvine Medical Center (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
NCT05498428
- Phase 2
- Ages 18 years and older
- Sex: All
Nearest site: University of California Irvine (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
NCT06128551
- Phase 1/2
- Ages 18 years and older
- Sex: All
Nearest site: UC IRVINE Health (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- Assess Diversity of Gut Microbiome in Met NSCLC in Correlation to Tx & Adverse Effects
NCT06221800
- Observational
- Ages 18 years and older
- Sex: All
Nearest site: Chao Family Comprehensive Cancer Center University of California, Irvine (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
NCT06580002
- Phase 2
- Ages 18 years and older
- Sex: All
Nearest site: Chao Family Comprehensive Cancer Center, University of California Irvine (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer
NCT07062172
- Interventional
- Ages 18 to 80 years
- Sex: All
Nearest site: Chao Family Comprehensive Cancer Center University of California, Irvine (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
NCT07064018
- Phase 1/2
- Ages 18 years and older
- Sex: All
Nearest site: Chao Family Comprehensive Cancer Center University of California, Irvine (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
NCT07447050
- Phase 2
- Ages 18 years and older
- Sex: All
Nearest site: Chao Family Comprehensive Cancer Center, University of California Irvine (Orange, CA)
- Distance to nearest recruiting site
- <1 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
NCT03851445
- Phase 2/3
- Ages 18 years and older
- Sex: All
Nearest sites: Kaiser Permanente-Anaheim (Anaheim, CA); City of Hope at Irvine Lennar (Irvine, CA)
- Distance to nearest recruiting site
- ~5 mi (city-level)
- Recruiting sites
- 23 sites within 50 mi
- Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
NCT06616584
- Phase 2/3
- Ages 18 years and older
- Sex: All
Nearest sites: Kaiser Permanente-Anaheim (Anaheim, CA); City of Hope at Irvine Lennar (Irvine, CA)
- Distance to nearest recruiting site
- ~5 mi (city-level)
- Recruiting sites
- 20 sites within 50 mi
- Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
NCT07222566
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Oncura Health - Anaheim (Anaheim, CA); Memorial Care Orange Coast Medical Center Attn (Fountain Valley, CA)
- Distance to nearest recruiting site
- ~5 mi (city-level)
- Recruiting sites
- 16 sites within 50 mi
- Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
NCT04267848
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Kaiser Permanente-Anaheim (Anaheim, CA); Kaiser Permanente-Irvine (Irvine, CA)
- Distance to nearest recruiting site
- ~5 mi (city-level)
- Recruiting sites
- 13 sites within 50 mi
- A Study of Sigvotatug Vedotin in Advanced Solid Tumors
NCT04389632
- Phase 1
- Ages 18 years and older
- Sex: All
Nearest sites: Providence Medical Foundation (Anaheim, CA); Providence Medical Foundation (Fullerton, CA)
- Distance to nearest recruiting site
- ~5 mi (city-level)
- Recruiting sites
- 7 sites within 50 mi
- A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
NCT06692738
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Research Site (Anaheim, CA); Research Site (Los Alamitos, CA)
- Distance to nearest recruiting site
- ~5 mi (city-level)
- Recruiting sites
- 5 sites within 50 mi
- Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
NCT04613596
- Phase 2/3
- Ages 18 years and older
- Sex: All
Nearest sites: Providence - Saint Joseph Home Health - Anaheim (Anaheim, CA); TRIO - Cancer & Blood Specialty Clinic - Los Alamitos (Los Alamitos, CA)
- Distance to nearest recruiting site
- ~5 mi (city-level)
- Recruiting sites
- 4 sites within 50 mi
- A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
NCT06627647
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Research Site (Anaheim, CA); Research Site (Beverly Hills, CA)
- Distance to nearest recruiting site
- ~5 mi (city-level)
- Recruiting sites
- 4 sites within 50 mi
- Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
NCT06357533
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Research Site (Anaheim, CA); Research Site (Fountain Valley, CA)
- Distance to nearest recruiting site
- ~5 mi (city-level)
- Recruiting sites
- 3 sites within 50 mi
- Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
NCT06801834
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest site: Los Angeles Cancer Network (Anaheim, CA)
- Distance to nearest recruiting site
- ~5 mi (city-level)
- Recruiting sites
- 1 site within 50 mi
- Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers
NCT07227298
- Phase 1/2
- Ages 18 years and older
- Sex: All
Nearest sites: Providence Medical Foundation (Fullerton, CA); Providence St. Jude Medical Center (Fullerton, CA)
- Distance to nearest recruiting site
- ~7 mi (city-level)
- Recruiting sites
- 9 sites within 50 mi
- Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
NCT05098132
- Phase 1/2
- Ages 18 years and older
- Sex: All
Nearest sites: Providence Medical Foundation (Fullerton, CA); Hoag Memorial Hospital Presbyterian (Newport Beach, CA)
- Distance to nearest recruiting site
- ~7 mi (city-level)
- Recruiting sites
- 5 sites within 50 mi
- A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
NCT06623422
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Providence St. Jude Medical Center ( Site 0106) (Fullerton, CA); VA Long Beach Healthcare System ( Site 0199) (Long Beach, CA)
- Distance to nearest recruiting site
- ~7 mi (city-level)
- Recruiting sites
- 4 sites within 50 mi
- This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
NCT06758401
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Providence Medical Foundation (Fullerton, CA); Providence St. Jude Medical Center (Fullerton, CA)
- Distance to nearest recruiting site
- ~7 mi (city-level)
- Recruiting sites
- 4 sites within 50 mi
- Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
NCT05297734
- Interventional
- Ages 18 years and older
- Sex: All
Nearest sites: St Jude Heritage Medical Group (Fullerton, CA); Beckman Research Institute of City of Hope (Duarte, CA)
- Distance to nearest recruiting site
- ~7 mi (city-level)
- Recruiting sites
- 3 sites within 50 mi
- First in Human Study of TORL-1-23 in Participants With Advanced Cancer
NCT05103683
- Phase 1
- Ages 18 years and older
- Sex: All
Nearest sites: Providence Medical Foundation (Fullerton, CA); UCLA - JCCC Clinical Research Unit (Los Angeles, CA)
- Distance to nearest recruiting site
- ~7 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
NCT06203210
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: Clinical Research Providence Medical Foundation (Fullerton, CA); UCLA Hematology-Oncology (Los Angeles, CA)
- Distance to nearest recruiting site
- ~7 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
- LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
NCT06216301
- Phase 3
- Ages 18 years and older
- Sex: All
Nearest sites: St. Jude Herritage Medical Group (Fullerton, CA); Hoag Family Cancer Institute - Hoag Memorial Hospital (Newport Beach, CA)
- Distance to nearest recruiting site
- ~7 mi (city-level)
- Recruiting sites
- 2 sites within 50 mi
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Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.