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Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

NCT07100080

This study is recruiting at 23 US sites in 13 states, according to its ClinicalTrials.gov record last updated .

Summary

A Study of Izalontamab Brengitecan (BMS-986507) versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer after failure of EGFR TKI Therapy

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Non-Small Cell Lung Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2/3
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Bristol-Myers Squibb
Last updated on ClinicalTrials.gov
October 9, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 2

  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care building · Irvine, CA
  • University of California, Irvine (UCI) Health - UC Irvine Medical Center · Orange, CA

Colorado · 1

  • Shaw Cancer Center · Edwards, CO

Georgia · 2

  • Piedmont Healthcare · Atlanta, GA
  • John B Amos Cancer Center · Columbus, GA

Illinois · 1

  • Rush University Medical Center · Chicago, IL

Massachusetts · 1

  • Dana-Farber Cancer Institute · Boston, MA

Missouri · 1

  • Washington University School of Medicine · St Louis, MO

Nevada · 1

  • Renown Regional Medical Center · Reno, NV

New York · 4

  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island · Mineola, NY
  • NYU Langone Health · New York, NY
  • Weill Cornell Medical College · New York, NY
  • Rochester General Hospital Infectious Disease · Rochester, NY

Ohio · 2

  • University Hospitals Cleveland Medical Center · Cleveland, OH
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C · Columbus, OH

Oregon · 3

  • Oregon Health and Science University · Portland, OR
  • Providence Cancer Institute Franz Clinic · Portland, OR
  • Providence St. Vincent Medical Center · Portland, OR

Pennsylvania · 2

  • Hospital of the University of Pennsylvania · Philadelphia, PA
  • West Penn Allegheny Health · Pittsburgh, PA

Tennessee · 1

  • Tennessee Oncology · Nashville, TN

Virginia · 2

  • University of Virginia Health System · Charlottesville, VA
  • Virginia Commonwealth University (Vcu) · Richmond, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.