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Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

NCT07227298

This study is recruiting at 44 US sites in 9 states, according to its ClinicalTrials.gov record last updated .

Summary

This study is being done to learn more about a new medicine called PF-08634404 and how it works when used with other cancer medicines in people who have advanced solid tumors. An advanced solid tumor is a type of cancer that has spread beyond its original location and cannot be removed by surgery or cured with standard treatments.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Advanced/Metastatic Non-Small Cell Lung Cancer
  • Carcinoma, Non-Small Cell Lung
  • Non-Small Cell Lung Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1/2
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Pfizer
Last updated on ClinicalTrials.gov
October 8, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arkansas · 3

  • Highlands Oncology Group, PA · Fayetteville, AR
  • Highlands Oncology Group, PA · Rogers, AR
  • Highlands Oncology Group, PA · Springdale, AR

California · 12

  • Providence Medical Foundation · Fullerton, CA
  • Providence St. Jude Medical Center · Fullerton, CA
  • Providence St. Jude Medical Center - Virginia K. Crosson Cancer Center and Infusion Center · Fullerton, CA
  • Scripps Clinic Torrey Pines (Scripps Cancer Center) · La Jolla, CA
  • Scripps Green Hospital · La Jolla, CA
  • Scripps Shiley Pavilion · La Jolla, CA
  • LACN Century City · Los Angeles, CA
  • START Los Angeles, LLC · Los Angeles, CA
  • Valkyrie Clinical Trials · Los Angeles, CA
  • Valkyrie Clinical Trials (Additional Site Pharmacy Storage Suite) · Los Angeles, CA
  • Valkyrie Clinical Trials (Additional Site Suite) · Los Angeles, CA
  • Mission Community Hospital (Satellite Site) · Panorama City, CA

Colorado · 3

  • Rocky Mountain Cancer Centers,LLP · Aurora, CO
  • Rocky Mountain Cancer Centers,LLP · Denver, CO
  • Rocky Mountain Cancer Centers,LLP · Lone Tree, CO

Florida · 6

  • BRCR Medical Center Inc. · Coral Springs, FL
  • Mid Florida Hematology and Oncology Center · Orange City, FL
  • Orlando Health Ambulatory Care Center · Orlando, FL
  • Orlando Health Cancer Institute · Orlando, FL
  • Orlando Health Orlando Regional Medical Center · Orlando, FL
  • BRCR Global - Tamarac · Tamarac, FL

New Jersey · 6

  • Hackensack University Medical Center · Hackensack, NJ
  • John Theurer Cancer Center at Hackensack University Medical Center · Hackensack, NJ
  • Newman Street Imaging · Hackensack, NJ
  • John Theurer Cancer Center at JSUMC · Neptune City, NJ
  • John Theurer Cancer Center at From Road · Paramus, NJ
  • Heart Center Glenpointe · Teaneck, NJ

New York · 1

  • Montefiore Medical Center- Montefiore Medical Park · The Bronx, NY

Oregon · 1

  • Oncology Associates of Oregon, P.C. · Eugene, OR

Texas · 5

  • Dallas Cancer Specialists · Garland, TX
  • Lumi Research · Houston, TX
  • Southwest Oncology Associates · Houston, TX
  • US Oncology Investigational Products Center (IPC) · Irving, TX
  • Voyage Clinical · Sugar Land, TX

Virginia · 7

  • Massey Cancer Center Clinical & Translational Research Lab · Richmond, VA
  • VCU Health Stony Point · Richmond, VA
  • VCU Medical Center Gateway Building · Richmond, VA
  • Virginia Commonwealth University · Richmond, VA
  • Virginia Commonwealth University · Richmond, VA
  • VCU Health Community Memorial Hospital · South Hill, VA
  • VCU Health Tappahannock Hospital · Tappahannock, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.