Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
NCT05379985
This study is recruiting at 21 US sites in 13 states, according to its ClinicalTrials.gov record last updated .
Summary
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Non-small Cell Lung Cancer (NSCLC)
- Colorectal Cancer (CRC)
- Pancreatic Ductal Adenocarcinoma (PDAC)
- Advanced Solid Tumors
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 1/2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Revolution Medicines, Inc.
- Last updated on ClinicalTrials.gov
- May 15, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 2
- UC Irvine/Chao Family Comprehensive Cancer Center · Orange, CA
- UCLA · Santa Monica, CA
Florida · 1
- Moffitt Cancer Center · Tampa, FL
Georgia · 1
- Piedmont Healthcare · Atlanta, GA
Louisiana · 1
- Mary Bird Perkins Cancer Center · Baton Rouge, LA
Maryland · 1
- Johns Hopkins University · Baltimore, MD
Massachusetts · 1
- Dana Farber Cancer Institute · Boston, MA
New York · 3
- Columbia University · New York, NY
- Memorial Sloan-Kettering Cancer Center · New York, NY
- Perlmutter Cancer Center at NYU Langone Health · New York, NY
Ohio · 2
- Christ Hospital Cancer Center · Cincinnati, OH
- Taylor Cancer Research Center · Maumee, OH
Tennessee · 2
- Tennessee Oncology · Chattanooga, TN
- Sarah Cannon Research Institute · Nashville, TN
Texas · 4
- University of Texas at Austin · Austin, TX
- Mary Crowley Cancer Research · Dallas, TX
- The University of Texas MD Anderson Cancer Center · Houston, TX
- Next Oncology · San Antonio, TX
Utah · 1
- Huntsman Cancer Institute · Salt Lake City, UT
Virginia · 1
- Next Oncology Virginia · Fairfax, VA
Washington · 1
- Virginia Mason Medical Center · Seattle, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.