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Heart Failure Clinical Trials near Chicago, IL

43 studies for Heart Failure are recruiting at 98 sites within 50 miles of Chicago, Illinois, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Heart Failure trials in the US or all trials near Chicago.

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Heart Failure studies enrolling near Chicago

Showing 43 studies, nearest first.
  1. A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

    NCT06424288

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Illinois Masonic Hospital (Chicago, IL); AMR Park Ridge (Park Ridge, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  2. Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

    NCT06677060

    • Phase 3
    • Ages 40 years and older
    • Sex: All

    Nearest sites: Research Site (Chicago, IL); Research Site (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  3. A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)

    NCT06991257

    • Phase 2
    • Ages 18 to 79 years
    • Sex: All

    Nearest sites: NMH Clinical Research Unit (Chicago, IL); Northwestern Memorial HealthCare - Arkes Pavilion (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  4. A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

    NCT07567001

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Chicago Clinical Research Institute INC (Chicago, IL); Eagle Clinical Research (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  5. A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

    NCT06008197

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Chicago, IL Investigative Site 10062 (Chicago, IL); Glenview, IL Investigative Site 10021 (Glenview, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  6. Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

    NCT06307652

    • Phase 3
    • Ages 18 to 130 years
    • Sex: All

    Nearest sites: Research Site (Chicago, IL); Research Site (Hazel Crest, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  7. AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

    NCT06378632

    • Observational
    • Ages 22 years and older
    • Sex: All

    Nearest sites: Advocate Illinois Masonic Medical Center (Chicago, IL); University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  8. His-Bundle Corrective Pacing in Heart Failure

    NCT05265520

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Northwestern Memorial Hospital (Chicago, IL); Rush University Medical Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  9. Left vs Left Randomized Clinical Trial

    NCT05650658

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Rush University (Chicago, IL); University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  10. Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

    NCT05677100

    • Interventional
    • Ages 21 years and older
    • Sex: All

    Nearest sites: Advocate IMMC (Chicago, IL); University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  11. Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

    NCT06310031

    • Interventional
    • Ages 18 to 100 years
    • Sex: All

    Nearest sites: Advocate Christ Medical Center (Chicago, IL); Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  12. Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

    NCT04592445

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest sites: Bluhm Cardiovascular Institute of Northwestern University (Chicago, IL); University of Chicago Medical Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  13. Cardiogenic Shock Working Group Registry

    NCT04682483

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Northwestern Medicine (Chicago, IL); University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  14. iCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure

    NCT06205225

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Rush University Medical Center (Chicago, IL); University of Illinois Hospital & Health Sciences System (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  15. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

    NCT06526195

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: University of Chicago (Chicago, IL); Advocate Health & Hospitals Corporation (Oakbrook Terrace, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  16. A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

    NCT07219511

    • Phase 1
    • Ages 50 years and older
    • Sex: All

    Nearest sites: Eagle Clinical Research (Chicago, IL); Chicago Medical Research (Hazel Crest, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  17. A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

    NCT05489705

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Chicago Dept of Medicine (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Cardiac Power Output in Cardiogenic Shock Patients

    NCT05700617

    • Early Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: The University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets

    NCT05873634

    • Observational
    • Ages 30 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

    NCT06039176

    • Observational
    • Ages 18 to 100 years
    • Sex: All

    Nearest site: University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

    NCT06217302

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Northwestern University Feinberg School of Medicine (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

    NCT06517186

    • Observational
    • Ages 30 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure

    NCT06526988

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs

    NCT06532890

    • Observational
    • Ages Up to 18 years
    • Sex: All

    Nearest site: Ann & Robert H. Lurie Children's Hospital of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)

    NCT06641362

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Chicago (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. ELEVATE-HFpEF Clinical Study

    NCT06678841

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest site: The University of Chicago Medical Center (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

    NCT06895070

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Northwestern Memorial Hospital (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)

    NCT07059962

    • Observational
    • Ages 21 years and older
    • Sex: All

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. UIC Multi-Ethnic DCM Registry

    NCT07145138

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: University of Illinois Hospital & Health Sciences (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF

    NCT07324772

    • Interventional
    • Ages 60 to 99 years
    • Sex: All

    Nearest site: Northwestern University (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Study of the Progression of Chronic Cardiovascular Conditions

    NCT07420907

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Prolaio (Chicago, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

    NCT05996328

    • Interventional
    • Ages 60 years and older
    • Sex: All

    Nearest site: Edward Hines Jr. VA Hospital, Hines, IL (Hines, IL)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

    NCT06935370

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: AMR Park Ridge (Park Ridge, IL); Chicago Medical Research (Hazel Crest, IL)

    Distance to nearest recruiting site
    ~15 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  34. Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

    NCT07069738

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of Chicago (Hinsdale, IL)

    Distance to nearest recruiting site
    ~15 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

    NCT05934487

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Heart Care Centers of Illinois (HCCI) (Palos Park, IL); Advocate Health System (Downers Grove, IL)

    Distance to nearest recruiting site
    ~16 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  36. A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

    NCT06024746

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: CON-10021, Glenview, IL (Glenview, IL); CON-10025, Naperville, IL (Naperville, IL)

    Distance to nearest recruiting site
    ~17 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  37. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

    NCT03142152

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Advocate Good Samaritan (Downers Grove, IL); Midwest Cardiovascular Institute (MCI) (Naperville, IL)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  38. Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

    NCT07037459

    • Phase 3
    • Ages 18 to 99 years
    • Sex: All

    Nearest sites: Chicago Medical Research LLC (Hazel Crest, IL); Cardiovascular Research of Northwest Indiana LLC (Munster, IN)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  39. Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

    NCT06736574

    • Phase 3
    • Ages 18 to 85 years
    • Sex: All

    Nearest sites: Cardiovascular Research of Northwest Indiana, LLC. (Munster, IN); Midwest Cardiovascular Institute (Naperville, IL)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  40. Alleviant ALLAY-HF Study

    NCT05685303

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest site: Midwest Cardiovascular Institute (Naperville, IL)

    Distance to nearest recruiting site
    ~26 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure

    NCT06783335

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Endotronix (Naperville, IL)

    Distance to nearest recruiting site
    ~26 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. Alleviant ALLAY-HFrEF Study

    NCT06812533

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Midwest Cardiovascular Institute (Naperville, IL)

    Distance to nearest recruiting site
    ~26 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

    NCT06033950

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: FIN-10064, Merrillville, IN (Merrillville, IN)

    Distance to nearest recruiting site
    ~30 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Heart Failure clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.