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Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs

NCT06532890

This study is recruiting at 7 US sites in 7 states, according to its ClinicalTrials.gov record last updated .

Summary

This study aims to discover circulating microRNAs (associated with drug doses and levels) that can be used to characterize the overall immune state in pediatric heart transplant patients and predict patients that will go on to develop infection and rejection. MicroRNAs (miRs) are small, non-coding RNA molecules that regulate gene expression and serve as molecular biomarkers found in the circulation.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Cardiac Failure
  • Graft Rejection

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
Up to 18 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Northwestern University
Last updated on ClinicalTrials.gov
August 25, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Colorado · 1

  • Children's Hospital Colorado · Aurora, CO

Illinois · 1

  • Ann & Robert H. Lurie Children's Hospital of Chicago · Chicago, IL

Michigan · 1

  • University of Michigan · Ann Arbor, MI

New York · 1

  • Columbia University · New York, NY

Pennsylvania · 1

  • University of Pittsburgh · Pittsburgh, PA

Tennessee · 1

  • Vanderbilt University · Nashville, TN

Texas · 1

  • Texas Children's Hospital · Houston, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.