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Heart Failure Clinical Trials near Boston, MA

45 studies for Heart Failure are recruiting at 61 sites within 50 miles of Boston, Massachusetts, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Heart Failure trials in the US or all trials near Boston.

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Recruiting now

Heart Failure studies enrolling near Boston

Showing 45 studies, nearest first.
  1. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

    NCT03142152

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Beth Israel Deaconess (Boston, MA); Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  2. Alleviant ALLAY-HFrEF Study

    NCT06812533

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Boston Medical Center (Boston, MA); Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  3. US Benchmarking Clinical Study

    NCT07215715

    • Observational
    • Ages 60 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Boston Medical Center (Boston, MA); Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  4. Home Hospital for Suddenly Ill Adults

    NCT03524222

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Brigham and Women's Faulkner Hospital (Boston, MA); Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  5. Cardiogenic Shock Working Group Registry

    NCT04682483

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Beth Israel Deaconess Medical Center (Boston, MA); Tufts Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  6. A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

    NCT05489705

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Harvard (Massachusetts General Hospital) (Boston, MA); Harvard Medical School - Brigham and Women's Hospital (BWH) (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  7. Left vs Left Randomized Clinical Trial

    NCT05650658

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Beth Israel Deaconess Medical Center (Boston, MA); Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  8. Alleviant ALLAY-HF Study

    NCT05685303

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest sites: Boston Medical Center (Boston, MA); Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  9. Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF

    NCT05934565

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest sites: BIDMC (Boston, MA); VA Boston (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  10. A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

    NCT06008197

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Boston, MA Investigative Stie 10087 (Boston, MA); Providence, RI Investigative Site 10050 (Providence, RI)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  11. Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

    NCT06307652

    • Phase 3
    • Ages 18 to 130 years
    • Sex: All

    Nearest sites: Research Site (Boston, MA); Research Site (Providence, RI)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  12. Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

    NCT06310031

    • Interventional
    • Ages 18 to 100 years
    • Sex: All

    Nearest sites: Massachusetts General Hospital (Boston, MA); Tufts Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  13. Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

    NCT06677060

    • Phase 3
    • Ages 40 years and older
    • Sex: All

    Nearest sites: Research Site (Boston, MA); Research Site (Roslindale, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  14. Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

    NCT00271180

    • Observational
    • Ages Any age
    • Sex: All

    Nearest site: (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure

    NCT03480633

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Imaging Histone Deacetylase in the Heart

    NCT03549559

    • Interventional
    • Ages 18 to 85 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. Promoting Well-being and Health in Heart Failure

    NCT04829617

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Assessment of CCM in HF With Higher Ejection Fraction

    NCT05064709

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

    NCT05327062

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. Pulmonary Artery Catheter in Cardiogenic Shock Trial

    NCT05485376

    • Interventional
    • Ages 18 to 90 years
    • Sex: All

    Nearest site: Tufts Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF

    NCT05577819

    • Interventional
    • Ages 65 years and older
    • Sex: All

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure

    NCT05627440

    • Interventional
    • Ages 18 to 100 years
    • Sex: All

    Nearest site: Tufts Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

    NCT05714085

    • Phase 2/3
    • Ages 29 days to 17 years
    • Sex: All

    Nearest site: Boston Children's Hospital ( Site 0035) (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

    NCT05934487

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Tufts Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Purinergic Signaling and the Postmenopausal Heart

    NCT06015776

    • Observational
    • Ages 30 to 88 years
    • Sex: All

    Nearest site: Beth Israel Deaconess Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. Care Transitions App for Patients With Multiple Chronic Conditions

    NCT06051058

    • Interventional
    • Ages 55 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System

    NCT06147336

    • Interventional
    • Ages 22 to 88 years
    • Sex: All

    Nearest site: One Boston Medical Center Place (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. The STOP-MED CTRCD Trial

    NCT06183437

    • Phase 4
    • Ages 18 years and older
    • Sex: All

    Nearest site: Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

    NCT06217302

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Joslin Diabetes Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC

    NCT06228924

    • Phase 1
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure

    NCT06253104

    • Observational
    • Ages 18 to 100 years
    • Sex: All

    Nearest site: Tufts Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

    NCT06311708

    • Observational
    • Ages 14 to 65 years
    • Sex: All

    Nearest site: Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

    NCT06517186

    • Observational
    • Ages 30 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Mass General Brigham (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

    NCT06526195

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. ELEVATE-HFpEF Clinical Study

    NCT06678841

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest site: Tufts Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

    NCT06736574

    • Phase 3
    • Ages 18 to 85 years
    • Sex: All

    Nearest site: Tufts Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF

    NCT06793371

    • Phase 2
    • Ages 40 to 85 years
    • Sex: All

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

    NCT06939751

    • Observational
    • Ages 18 to 99 years
    • Sex: All

    Nearest site: Tufts Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. CCM OPEN HF Registry

    NCT07112924

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)

    NCT07202000

    • Phase 2
    • Ages 40 years and older
    • Sex: All

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

    NCT07214376

    • Interventional
    • Ages 18 to 85 years
    • Sex: All

    Nearest site: Boston Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. Targeted Artificial Intelligence Language mOdel Recommendations for Heart Failure (TAILOR-HF)

    NCT07337577

    • Interventional
    • Ages 18 to 85 years
    • Sex: All

    Nearest site: Mass General Brigham (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. Diffusion MRI in Heart Failure

    NCT02973633

    • Early Phase 1
    • Ages 18 to 85 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Charlestown, MA)

    Distance to nearest recruiting site
    ~1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. Supporting Health in Veterans With Heart Failure

    NCT05839067

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: VA Clinic - Providence (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

    NCT07069738

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Southcoast Physicians Group (Fall River, MA)

    Distance to nearest recruiting site
    ~46 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Heart Failure clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.