AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
NCT06793371
This study is recruiting at 24 US sites in 16 states, according to its ClinicalTrials.gov record last updated .
Summary
This is a Phase 2 dose-finding study in adult participants with symptomatic HFpEF.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 40 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Cytokinetics
- Last updated on ClinicalTrials.gov
- August 27, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- Eastern Shore Research Institute, LLC · Fairhope, AL
Arizona · 1
- University of Arizona Sarver Heart Center · Tucson, AZ
Arkansas · 1
- John L. McClellan Memorial Veterans Hospital · Little Rock, AR
California · 5
- BioSolutions Clinical Research Center · Imperial, CA
- Profound Research LLC · Pasadena, CA
- University of California, San Francisco - Heart and Vascular Center · San Francisco, CA
- FOMAT - Comprehensive Cardiovascular Care · Santa Maria, CA
- Blue Coast Research Center, LLC · Vista, CA
Florida · 3
- Las Mercedes Medical Research · Hialeah, FL
- New Generation of Medical Research · Hialeah, FL
- Cleveland Clinic Florida · Weston, FL
Illinois · 1
- Methodist Medical Center of Illinois · Peoria, IL
Massachusetts · 1
- Massachusetts General Hospital · Boston, MA
Minnesota · 1
- Mayo Clinic · Rochester, MN
Missouri · 1
- Washington University Center for Advanced Medicine · St Louis, MO
New Jersey · 1
- Morristown Medical Center · Morristown, NJ
New York · 2
- Mount Sinai West · New York, NY
- NYU Langone Health · New York, NY
Ohio · 1
- The Lindner Center for Research & Education at The Christ Hospital · Cincinnati, OH
Oregon · 1
- Oregon Health and Science University · Portland, OR
Texas · 2
- University of Texas Southwestern Medical Center, Dallas · Dallas, TX
- Center for Advanced Heart Failure · Houston, TX
Washington · 1
- Swedish Heart & Vascular Institute, Advanced Cardiac Support Program · Seattle, WA
Wisconsin · 1
- Froedtert Hospital - Center for Advanced Care · Milwaukee, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.