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Breast Cancer Clinical Trials near St Louis, MO

92 studies for Breast Cancer are recruiting at 230 sites within 50 miles of St Louis, Missouri, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Breast Cancer trials in the US or all trials near St Louis.

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Recruiting now

Breast Cancer studies enrolling near St Louis

Showing the 50 nearest of 92 studies.
  1. Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

    NCT05929768

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    17 sites within 50 mi
  2. Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

    NCT05879926

    • Phase 3
    • Ages 18 to 60 years
    • Sex: Female

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    16 sites within 50 mi
  3. Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

    NCT05564377

    • Phase 2
    • Ages Any age
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    12 sites within 50 mi
  4. Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

    NCT05812807

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    12 sites within 50 mi
  5. Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

    NCT06058377

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    12 sites within 50 mi
  6. ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

    NCT06876714

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    12 sites within 50 mi
  7. S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

    NCT03723928

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    11 sites within 50 mi
  8. Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

    NCT05334069

    • Observational
    • Ages 40 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    11 sites within 50 mi
  9. Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

    NCT06418204

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    11 sites within 50 mi
  10. Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

    NCT06500481

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital South (St Louis, MO); Siteman Cancer Center at Christian Hospital (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    8 sites within 50 mi
  11. De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

    NCT04852887

    • Phase 3
    • Ages 50 to 70 years
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  12. S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

    NCT03418961

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital Saint Louis (St Louis, MO); Mercy Hospital South (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  13. Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

    NCT03606967

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Siteman Cancer Center at Christian Hospital (St Louis, MO); Siteman Cancer Center-South County (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  14. Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

    NCT07391774

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Missouri Baptist Medical Center (St Louis, MO); Cancer Care Center of O'Fallon (O'Fallon, IL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  15. A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

    NCT07062965

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Siteman Cancer Center (St Louis, MO); Siteman Cancer Center - North County (Florissant, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  16. E-Mindfulness Approaches for Living After Breast Cancer

    NCT06748222

    • Phase 3
    • Ages 18 to 50 years
    • Sex: All

    Nearest sites: Mercy Hospital South (St Louis, MO); Missouri Baptist Medical Center (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  17. Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

    NCT07327489

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Mercy Hospital - South (St Louis, MO); Mercy Hospital -STL (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  18. Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells

    NCT00353483

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score

    NCT02476786

    • Phase 2
    • Ages 70 years and older
    • Sex: Female

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

    NCT03053193

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. The PREDICT Registry:

    NCT03448926

    • Observational
    • Ages 30 to 85 years
    • Sex: Female

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    NCT03452774

    • Observational
    • Ages Any age
    • Sex: All

    Nearest site: Massive Bio SYNERGY-AI site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

    NCT04354064

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. Treatment Monitoring of Patients Receiving CDK 4/6 Inhibitors for Hormone Receptor (HR) Positive, HER2 Negative Metastatic Breast Cancer (MBC) With or Without the Addition of DiviTum® Serum Thymidine Kinase 1 (TK1) Activity Testing

    NCT04968964

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

    NCT04981119

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

    NCT05123482

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Research Site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

    NCT05216432

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine St. Louis (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

    NCT05232916

    • Phase 3
    • Ages 18 to 100 years
    • Sex: All

    Nearest site: Siteman Cancer Center - Washington University Medical Campus (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer

    NCT05304962

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

    NCT05490472

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Cryoablation vs Lumpectomy in T1 Breast Cancers

    NCT05505643

    • Interventional
    • Ages 50 years and older
    • Sex: Female

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

    NCT05633654

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

    NCT05696626

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

    NCT05768139

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. NeoTAILOR: ABiomarker-directed Approach to Guide Neoadjuvant Therapy for Patients With Stage II/III ER-positive, HER2-negative Breast Cancer

    NCT05837455

    • Phase 2
    • Ages 18 years and older
    • Sex: Female

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema

    NCT05890677

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine in St. Louis (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients

    NCT05972343

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast Cancer

    NCT05977036

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

    NCT06084481

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University /ID# 257379 (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

    NCT06103864

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Research Site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

    NCT06172478

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University, School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

    NCT06179303

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Siteman Cancer Center at Washington University (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

    NCT06184750

    • Phase 2
    • Ages 18 to 55 years
    • Sex: Female

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors

    NCT06188520

    • Phase 1/2
    • Ages 18 years and older
    • Sex: Female

    Nearest site: Research Site (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. A Phase 1/1b Study of IAM1363 in HER2 Cancers

    NCT06253871

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

    NCT06270706

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

    NCT06312176

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine ( Site 0076) (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

    NCT06369285

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

    NCT06374459

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Washington University School of Medicine (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  50. Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

    NCT06393374

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Siteman Cancer Center ( Site 0099) (St Louis, MO)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Breast Cancer clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.