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Heart Failure Clinical Trials near Cleveland, OH

33 studies for Heart Failure are recruiting at 35 sites within 50 miles of Cleveland, Ohio, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Heart Failure trials in the US or all trials near Cleveland.

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Recruiting now

Heart Failure studies enrolling near Cleveland

Showing 33 studies, nearest first.
  1. Left vs Left Randomized Clinical Trial

    NCT05650658

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Cleveland Clinic (Cleveland, OH); The MetroHealth System (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  2. Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

    NCT06736574

    • Phase 3
    • Ages 18 to 85 years
    • Sex: All

    Nearest sites: Cleveland Clinic (Cleveland, OH); University Hospitals Cleveland Medical Center (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  3. Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

    NCT00271180

    • Observational
    • Ages Any age
    • Sex: All

    Nearest site: (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  4. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

    NCT03142152

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  5. Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) Study

    NCT04191681

    • Phase 4
    • Ages 18 years and older
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  6. Assessment of CCM in HF With Higher Ejection Fraction

    NCT05064709

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Cleveland Clinic Foundation (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  7. The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

    NCT05427370

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University Hospitals Cleveland Medical Center (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  8. A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

    NCT05489705

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: University Hospitals Cleveland Medical Center (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  9. A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure

    NCT05627440

    • Interventional
    • Ages 18 to 100 years
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  10. CV Imaging of Metabolic Interventions

    NCT05650307

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Cardiovascular Innovation Research Center (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. Development of CIRC Technologies

    NCT05654272

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Cardiovascular Innovation Research Center (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. Alleviant ALLAY-HF Study

    NCT05685303

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

    NCT05714085

    • Phase 2/3
    • Ages 29 days to 17 years
    • Sex: All

    Nearest site: Cleveland Clinic-Cleveland Clinic Chidren's ( Site 0022) (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

    NCT05934487

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University Hospital (Cleveland) (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

    NCT05996328

    • Interventional
    • Ages 60 years and older
    • Sex: All

    Nearest site: Louis Stokes VA Medical Center, Cleveland, OH (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

    NCT06217302

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Cleveland Clinic Foundation (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC

    NCT06228924

    • Phase 1
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

    NCT06291922

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Cleveland Clinic Foundation (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

    NCT06310031

    • Interventional
    • Ages 18 to 100 years
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

    NCT06311708

    • Observational
    • Ages 14 to 65 years
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

    NCT06378632

    • Observational
    • Ages 22 years and older
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

    NCT06526195

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: The Cleveland Clinic Foundation (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. Alleviant ALLAY-HFrEF Study

    NCT06812533

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF

    NCT06849752

    • Observational
    • Ages 40 years and older
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

    NCT06898515

    • Interventional
    • Ages 22 years and older
    • Sex: All

    Nearest site: UH Cleveland Medical Center (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

    NCT06935370

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: VA Northeast Ohio Healthcare System (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. Longitudinal Validation of CIRC Technologies

    NCT07081711

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. The WiSE®-UP Study (The WiSE System Utilization & Performance Study)

    NCT07098858

    • Observational
    • Ages 22 years and older
    • Sex: All

    Nearest site: Cleveland Clinic Foundation (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Fluid Guided Heart Failure Treatment at the Cleveland Clinic

    NCT07205120

    • Interventional
    • Ages 21 years and older
    • Sex: All

    Nearest site: The Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

    NCT07214376

    • Interventional
    • Ages 18 to 85 years
    • Sex: All

    Nearest site: Cleveland Clinic (Cleveland, OH)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. A Nurse-Led Weight Monitoring Intervention For Heart Failure Quality of LIfe and Self-Care

    NCT07184541

    • Interventional
    • Ages 55 years and older
    • Sex: All

    Nearest site: Cleveland Clinic Avon Hospital (Avon, OH)

    Distance to nearest recruiting site
    ~18 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

    NCT06008197

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Akron, OH Investigative Site 10081 (Akron, OH)

    Distance to nearest recruiting site
    ~30 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

    NCT06033950

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: FIN-10081, Akron, OH (Akron, OH)

    Distance to nearest recruiting site
    ~30 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Heart Failure clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.