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Alzheimer's Disease Clinical Trials near Orange, CA

37 studies for Alzheimer's Disease are recruiting at 75 sites within 50 miles of Orange, California, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Alzheimer's Disease trials in the US or all trials near Orange.

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Recruiting now

Alzheimer's Disease studies enrolling near Orange

Showing 37 studies, nearest first.
  1. Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

    NCT06847321

    • Phase 2
    • Ages 55 to 80 years
    • Sex: All

    Nearest sites: ATP Clinical Research, Inc. (Orange, CA); Riverside Clinical Research (Riverside, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  2. A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

    NCT06887192

    • Phase 2
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: Clinical Site (Orange, CA); Clinical Site (Anaheim, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  3. A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease

    NCT07011745

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: ATP Clinical Research (Orange, CA); National Institute of Clinical Research (Garden Grove, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  4. A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

    NCT07633470

    • Phase 4
    • Ages 50 years and older
    • Sex: All

    Nearest sites: ATP Clinical Research, Inc - Orange (Orange, CA); Progeny Psychiatric Clinic - Irvine (Irvine, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  5. Trial-Ready Cohort-Down Syndrome (TRC-DS)

    NCT04165109

    • Observational
    • Ages 25 to 55 years
    • Sex: All

    Nearest site: University of California, Irvine School of Medicine, Co-Enrolling through ABC-DS Only (Orange, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  6. A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

    NCT05511363

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest site: ATP Clinical Research-302 W La Veta Ave (Orange, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  7. Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders

    NCT05929703

    • Interventional
    • Ages 70 years and older
    • Sex: All

    Nearest site: Saddleback Medical Center (Orange, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  8. Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

    NCT07177352

    • Phase 3
    • Ages 50 to 90 years
    • Sex: All

    Nearest sites: Syrentis Clinical Research (Santa Ana, CA); Irvine Center for Clinical Research (Irvine, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  9. A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

    NCT07033494

    • Phase 2
    • Ages 50 to 85 years
    • Sex: All

    Nearest sites: Syrentis Clinical Research ( Site 1001) (Santa Ana, CA); Irvine Clinical Research ( Site 1041) (Irvine, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  10. A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

    NCT07602582

    • Phase 3
    • Ages 55 years and older
    • Sex: All

    Nearest sites: Syrentis Clinical Research (Santa Ana, CA); Irvine Clinical Research (Irvine, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  11. A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

    NCT07717411

    • Phase 3
    • Ages 55 to 80 years
    • Sex: All

    Nearest sites: Syrentis Clinical Research (Santa Ana, CA); Irvine Center for Clinical Research (Irvine, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  12. Clinical Study of SNK01 in Participants With Moderate Alzheimer's Disease

    NCT06189963

    • Phase 1/2
    • Ages 40 to 85 years
    • Sex: All

    Nearest sites: Syrentis Clinical Research (Santa Ana, CA); Behavioral Research Specialists, LLC (Glendale, CA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  13. Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

    NCT05980949

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: Advanced Research Center, Inc. (Anaheim, CA); USC - The Memory and Aging Center (MAC) - Alzheimer Disease Research Center (ADRC) (Los Angeles, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  14. A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

    NCT06585787

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: Advanced Research Center, Inc. (Anaheim, CA); Inland Psychiatric Medical Group (IPMG)-Chino (Chino, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  15. A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

    NCT07011732

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: Advanced Research Center (ARC) - Anaheim (Anaheim, CA); The Neurology Group (Pomona, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  16. A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

    NCT06540833

    • Phase 2
    • Ages 55 years and older
    • Sex: All

    Nearest site: Advanced Research Center, Inc (Anaheim, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

    NCT06651567

    • Phase 2
    • Ages 55 years and older
    • Sex: All

    Nearest site: Advanced Research Center, Inc (Anaheim, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose Administration

    NCT07780383

    • Phase 1
    • Ages 18 to 80 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: CenExel ACT (Formerly Anaheim Clinical Trials; LLC) (Anaheim, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

    NCT06976203

    • Phase 3
    • Ages 60 to 85 years
    • Sex: All

    Nearest sites: Fullerton Neurology and Headache Center (Fullerton, CA); Irvine Clinical Research (Irvine, CA)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  20. A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

    NCT07094516

    • Phase 2
    • Ages 50 to 85 years
    • Sex: All

    Nearest sites: Irvine Center for Clinical Research (Irvine, CA); University of California at Los Angeles (Los Angeles, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  21. Biomarker Exploration in Aging, Cognition and Neurodegeneration

    NCT03860857

    • Phase 3
    • Ages 60 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: University of California, Irvine (Irvine, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

    NCT07589595

    • Phase 2
    • Ages 55 to 85 years
    • Sex: All

    Nearest site: Irvine Clinical Research (Irvine, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease

    NCT07599670

    • Phase 1/2
    • Ages 50 to 90 years
    • Sex: All

    Nearest site: Irvine Center for Clinical Research /ID# 277752 (Irvine, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. ACP-204 in Adults With Alzheimer's Disease Psychosis

    NCT06159673

    • Phase 2/3
    • Ages 55 to 95 years
    • Sex: All

    Nearest sites: ATP Clinical Research (Costa Mesa, CA); Havana Research Institute LLC (Pasadena, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  25. A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

    NCT06657768

    • Phase 1
    • Ages 45 to 85 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Collaborative Neuroscience Network - CNS (Los Alamitos, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

    NCT06808984

    • Phase 2
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: Shreenath Clinical Service - Lakewood (Lakewood, CA); Inland Psychiatric Medical Group. (Chino, CA)

    Distance to nearest recruiting site
    ~17 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  27. A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

    NCT06947941

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest site: Inland Psychiatric Medical Group. (Chino, CA)

    Distance to nearest recruiting site
    ~18 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

    NCT06976216

    • Phase 3
    • Ages 60 to 85 years
    • Sex: All

    Nearest sites: Healthy Brain Clinic (Long Beach, CA); Anderson Clinical Research (Redlands, CA)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  29. [18F]PI-2620 Phase 3 Histopathological Study

    NCT05641688

    • Phase 3
    • Ages 50 years and older
    • Sex: All

    Nearest sites: UC Los Angeles (Los Angeles, CA); Esperanza Clinical (Murrieta, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  30. Cardiac-Control Affecting Learning Through Mindfulness (CALM)

    NCT06410157

    • Interventional
    • Ages 50 to 70 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: University of Southern California (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Polyphenols and Cognitive Decline

    NCT06507254

    • Interventional
    • Ages 50 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: University of California, Los Angeles (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

    NCT06563895

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: University of California, Los Angeles (UCLA) - David Geffen School of Medicine (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Large-coil Parietal Repetitive Transcranial Magnetic Stimulation (rTMS) for Alzheimer Disease (AD)

    NCT06597942

    • Phase 1/2
    • Ages 55 to 100 years
    • Sex: All

    Nearest site: UCLA TMS Clinical and Research Service (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study

    NCT07224607

    • Interventional
    • Ages 55 to 89 years
    • Sex: All

    Nearest site: CSMC (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. Open-Label Extension Protocol to SNK01-AD01 Study

    NCT07228078

    • Phase 2
    • Ages 40 to 85 years
    • Sex: All

    Nearest site: Behavioral Research Specialists, LLC (Glendale, CA)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions

    NCT04684602

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Southern California Hospital at Culver City / Southern California Hospital at Hollywood / Multiple US-based Sub-Investigator Sites (Culver City, CA)

    Distance to nearest recruiting site
    ~35 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia

    NCT07284472

    • Phase 2/3
    • Ages 55 to 90 years
    • Sex: All

    Nearest site: Esperanza Clinical (Murrieta, CA)

    Distance to nearest recruiting site
    ~40 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining an Alzheimer's Disease clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.