A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
NCT07589595
This study is recruiting at 36 US sites in 15 states, according to its ClinicalTrials.gov record last updated .
Summary
The main purpose of this study is to evaluate whether treatment with donanemab slows the progression of cognitive (how we think, learn, remember, pay attention, and make decisions) and functional (how we are able to perform daily activities) decline. For each participant, the study will last one and a half years.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Cognitive Dysfunction
- Lewy Body Disease
- Synucleinopathies
- Amyloid
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 55 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Eli Lilly and Company
- Last updated on ClinicalTrials.gov
- November 4, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 2
- TrialSphere Corp · Chandler, AZ
- HonorHealth Research Institute · Scottsdale, AZ
California · 3
- Profound Research LLC · Carlsbad, CA
- Irvine Clinical Research · Irvine, CA
- Stanford Neuroscience Health Center · Palo Alto, CA
Colorado · 1
- CenExel Rocky Mountain Clinical Research · Englewood, CO
Connecticut · 1
- Ki Health Partners, LLc, dba New England Institute for Clinical Research · Stamford, CT
Florida · 11
- JEM Research Institute · Atlantis, FL
- VIN - Aventura · Aventura, FL
- Brain Matters Research · Delray Beach, FL
- Neuropsychiatric Research Center of Southwest Florida · Fort Myers, FL
- K2 Medical Research ORLANDO · Maitland, FL
- BRP-Kendal Lakes · Miami, FL
- Renstar Medical Research · Ocala, FL
- Charter Research - Orlando · Orlando, FL
- Axiom Brain Health LLC · Tampa, FL
- Palm Beach Neurology · West Palm Beach, FL
- Conquest Research · Winter Park, FL
Indiana · 1
- Indiana University Health Neuroscience Center · Indianapolis, IN
Massachusetts · 3
- K2 Medical Research - Foxborough · Foxborough, MA
- Neurology Center of New England · Foxborough, MA
- Headlands Eastern MA LLC · Plymouth, MA
Michigan · 1
- QUEST Research Institute · Farmington Hills, MI
Minnesota · 1
- Struthers Parkinson's Center · Golden Valley, MN
Missouri · 1
- Citizens Memorial Hospital District · Bolivar, MO
Oregon · 2
- Oregon Health and Science University · Portland, OR
- Summit Headlands · Portland, OR
Pennsylvania · 1
- Pennsylvania Hospital · Philadelphia, PA
Texas · 6
- Gadolin Research · Beaumont, TX
- Kerwin Medical Center · Dallas, TX
- Houston Methodist Hospital · Houston, TX
- The University of Texas Health Science Center at Houston · Houston, TX
- Central Texas Neurology Consultants · Round Rock, TX
- The University of Texas Health Science Center · San Antonio, TX
Virginia · 1
- Re:Cognition Health · Fairfax, VA
Washington · 1
- EvergreenHealth · Kirkland, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.