A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
NCT06585787
This study is recruiting at 44 US sites in 19 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to evaluate the safety and efficacy of KarXT in adult participants with mild to severe Alzheimer's Disease (AD) with moderate to severe psychosis related to AD.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Alzheimer Disease
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 55 to 90 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Last updated on ClinicalTrials.gov
- September 22, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 2
- Gilbert Neurology Partners - PLLC - Avacare · Gilbert, AZ
- Banner Alzheimer's Institute · Phoenix, AZ
California · 3
- Advanced Research Center, Inc. · Anaheim, CA
- Inland Psychiatric Medical Group (IPMG)-Chino · Chino, CA
- USC - The Memory and Aging Center (MAC) - Alzheimer Disease Research Center (ADRC) · Los Angeles, CA
Connecticut · 1
- University of Connecticut Health Center · Farmington, CT
Florida · 11
- Envision Trials LLC · Bonita Springs, FL
- Arrow Clinical Trials · Daytona Beach, FL
- Aqualane Clinical Research · Naples, FL
- Sensible HealthCare, LLC · Ocoee, FL
- Charter Research Orlando · Orlando, FL
- Combined Research Orlando Phase I-IV LLC · Orlando, FL
- Nova Psychiatry · Orlando, FL
- Guardian Angel Research · Tampa, FL
- Interventional Psychiatry of Tampa Bay · Tampa, FL
- Charter Research · The Villages, FL
- Premiere Research Institute at Palm Beach Neurology, PA · West Palm Beach, FL
Georgia · 1
- Agile Clinical Research Trials, LLC · Atlanta, GA
Massachusetts · 4
- McLean Hospital · Belmont, MA
- Tufts Medical Center - 800 Washington St - PPDS · Boston, MA
- Boston Neuro Research Center · North Dartmouth, MA
- Elixia Health - Springfield - Elixia - PPDS · Springfield, MA
Michigan · 1
- Neurobehavioral Medicine Group (NBMG) · Bloomfield Township, MI
Mississippi · 1
- Precise Research Centers · Flowood, MS
Missouri · 1
- Tekton Research, LLC - Saint Louis Psychiatry - PPDS · St Louis, MO
New Jersey · 1
- Advanced Memory Research Institute - CenExel - PPDS · Toms River, NJ
New York · 3
- Mid Hudson Medical Research PLLC · New Windsor, NY
- SUNY Upstate Medical University · Syracuse, NY
- Five Towns Neurology, PC · Woodmere, NY
North Carolina · 3
- Triad Clinical Trials - 515 College Rd · Greensboro, NC
- AMC Research, LLC - Flourish - PPDS · Matthews, NC
- West Clinical Research · Morehead City, NC
Ohio · 2
- Ohio State University · Columbus, OH
- Insight Clinical Trials LLC - Independence · Independence, OH
Oklahoma · 1
- The Rivus Wellness & Research Institute · Oklahoma City, OK
Rhode Island · 1
- Alzheimer's Disease and Memory Disorders Center at Rhode Island Hospital · Providence, RI
Tennessee · 1
- Vanderbilt Psychiatric Hospital · Nashville, TN
Texas · 5
- Senior Adults Specialty Research · Austin, TX
- Epic Medical Research LLC - DeSoto · DeSoto, TX
- Advanced Neuro Research Center - El Paso · El Paso, TX
- University Hills Clinical Research - 102 Decker Ct · Irving, TX
- Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases · San Antonio, TX
Virginia · 1
- Conquest Research, LLC - Virginia - Vienna · Vienna, VA
Washington · 1
- Northwest Clinical Research Center · Bellevue, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.