A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
NCT07011732
This study is recruiting at 22 US sites in 13 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC in adult participants with agitation related to Alzheimer's Disease.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Alzheimer Disease
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 55 to 90 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Bristol-Myers Squibb
- Last updated on ClinicalTrials.gov
- October 15, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 1
- Imaging Endpoints · Scottsdale, AZ
California · 3
- Advanced Research Center (ARC) - Anaheim · Anaheim, CA
- The Neurology Group · Pomona, CA
- Sunwise Clinical Research · Walnut Creek, CA
Florida · 4
- Flourish Research · Merritt Island, FL
- Combined Research Orlando (CRO) · Orlando, FL
- Progressive Medical Research · Port Orange, FL
- Hope Research Network - Miami · Virginia Gardens, FL
Maryland · 1
- CBH Health · Gaithersburg, MD
Massachusetts · 3
- Boston Center for Memory · Newton, MA
- Mayflower Clinical Research · South Dartmouth, MA
- Voltaire Springfield · Springfield, MA
Michigan · 2
- NeuroBehavioral Medicine Group · Bloomfield Hills, MI
- Oakland Medical Research · Troy, MI
Nevada · 1
- Redbird Research · Las Vegas, NV
New Jersey · 1
- Global Medical Institutes LLC; Princeton Medical Institute · Princeton, NJ
New York · 2
- Mid Hudson Medical Research · New Windsor, NY
- Five Towns Neurology PC -Woodmere - 923 Broadway · Woodmere, NY
Oklahoma · 1
- Central States Research · Tulsa, OK
Texas · 1
- Advanced Neurology Epilepsy and Sleep Center · El Paso, TX
Utah · 1
- Wasatch Clinical Research, LLC · Salt Lake City, UT
Vermont · 1
- The Memory Clinic · Bennington, VT
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.