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Alzheimer's Disease Clinical Trials near Boston, MA

49 studies for Alzheimer's Disease are recruiting at 66 sites within 50 miles of Boston, Massachusetts, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Alzheimer's Disease trials in the US or all trials near Boston.

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Alzheimer's Disease studies enrolling near Boston

Showing 49 studies, nearest first.
  1. A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

    NCT06585787

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: Tufts Medical Center - 800 Washington St - PPDS (Boston, MA); McLean Hospital (Belmont, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  2. Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

    NCT07177352

    • Phase 3
    • Ages 50 to 90 years
    • Sex: All

    Nearest sites: Adams Clinical Boston (Boston, MA); Adams Clinical Watertown (Watertown, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  3. Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

    NCT06563895

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Boston University (BU) School of Medicine (Boston, MA); Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  4. Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

    NCT06847321

    • Phase 2
    • Ages 55 to 80 years
    • Sex: All

    Nearest sites: Adams Clinical Boston (Boston, MA); Adams Clinical Watertown (Watertown, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  5. Dominantly Inherited Alzheimer Network (DIAN)

    NCT00869817

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Brigham and Women's Hospital (Boston, MA); Butler Hospital (Providence, RI)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  6. Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

    NCT05776641

    • Interventional
    • Ages 55 to 90 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Massachusetts General Hospital (Boston, MA); Massachusetts Institute of Technology (Cambridge, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  7. PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases

    NCT02649985

    • Phase 1/2
    • Ages 18 to 85 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Brigham MS Center, 60 Fenwood Road (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  8. Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

    NCT04124029

    • Observational
    • Ages 30 to 90 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  9. Trial-Ready Cohort-Down Syndrome (TRC-DS)

    NCT04165109

    • Observational
    • Ages 25 to 55 years
    • Sex: All

    Nearest site: Massachusetts General Hospital, Co-Enrolling through ABC-DS Only (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  10. Assess Fibrin in Brains With AD/ADRD

    NCT05336695

    • Phase 1/2
    • Ages 55 to 90 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)

    NCT05658913

    • Observational
    • Ages 18 to 120 years
    • Sex: All

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

    NCT05661084

    • Interventional
    • Ages 55 years and older
    • Sex: All

    Nearest site: Hinda and Arthur Marcus Institute for Aging Research (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

    NCT05881239

    • Observational
    • Ages 18 to 100 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. Cognitive Neurology Unit Clinical Registry

    NCT05925621

    • Observational
    • Ages 50 to 95 years
    • Sex: All

    Nearest site: Beth Israel Deaconess Medical Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

    NCT05950607

    • Interventional
    • Ages 60 to 106 years
    • Sex: All

    Nearest site: Hebrew SeniorLife (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Gamma-Music Based Intervention for Mild Alzheimer's Disease

    NCT05984524

    • Interventional
    • Ages 50 to 95 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Northeastern University (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

    NCT06094192

    • Interventional
    • Ages 50 to 100 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: 111 Cummington Mall. Room 264 (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease

    NCT06489548

    • Phase 2
    • Ages 60 to 85 years
    • Sex: All

    Nearest site: Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

    NCT06538311

    • Early Phase 1
    • Ages 40 to 99 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

    NCT06651567

    • Phase 2
    • Ages 55 years and older
    • Sex: All

    Nearest site: Tufts University School of Medicine (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Mindfulness for Cognition in Early-stage Alzheimer's Disease

    NCT06792877

    • Interventional
    • Ages 50 to 100 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: VA Boston Healthcare System - Jamaica Plain Campus (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. TMS for Cognitive Decline in Aging and Preclinical AD

    NCT06956300

    • Interventional
    • Ages 40 to 99 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. Biomarker-based Trial of NPC-1 for Alzheimer's Pathology

    NCT07236190

    • Phase 2
    • Ages 55 years and older
    • Sex: All

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease

    NCT07659964

    • Interventional
    • Ages 50 to 90 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Boston University Neuromotor Recovery Laboratory (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease

    NCT05904132

    • Interventional
    • Ages 50 to 80 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Charlestown, MA)

    Distance to nearest recruiting site
    ~1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. Gamma Frequency Stimulation in Individuals With Down Syndrome

    NCT05196984

    • Interventional
    • Ages 25 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts Institute of Technology (Cambridge, MA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy

    NCT05655195

    • Interventional
    • Ages 65 to 100 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts Institute of Technology (Cambridge, MA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)

    NCT07496918

    • Phase 2
    • Ages 18 to 100 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: MIT (Cambridge, MA)

    Distance to nearest recruiting site
    ~3 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

    NCT06821568

    • Interventional
    • Ages 65 to 90 years
    • Sex: All

    Nearest site: Hebrew Rehabilitation Center (Roslindale, MA)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

    NCT07633470

    • Phase 4
    • Ages 50 years and older
    • Sex: All

    Nearest sites: Adams Clinical - Watertown (Watertown, MA); ActivMed Practices & Research, LLC (Methuen, MA)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  31. Triage Survey for Neurology Research Eligibility

    NCT06104852

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Adams Clinical (Watertown, MA)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease

    NCT07599670

    • Phase 1/2
    • Ages 50 to 90 years
    • Sex: All

    Nearest site: Adams Clinical /ID# 277754 (Watertown, MA)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

    NCT05245903

    • Observational
    • Ages 18 to 89 years
    • Sex: All

    Nearest site: McLean Hospital (Belmont, MA)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. Making Connections Thru Music

    NCT06079216

    • Interventional
    • Ages 18 to 103 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Hopeful Aging (Winchester, MA); The Hearthstone Institute, LLC (Winchester, MA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  35. The BRAIN App (Phase 2 SBIR)

    NCT06298474

    • Interventional
    • Ages 65 years and older
    • Sex: All

    Nearest site: Hopeful Aging (Winchester, MA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

    NCT06976216

    • Phase 3
    • Ages 60 to 85 years
    • Sex: All

    Nearest sites: Boston Center for Memory (Newton, MA); Rhode Island Mood & Memory Research Institute (East Providence, RI)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  37. A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

    NCT06937229

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest site: Boston Center for Memory (Newton, MA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

    NCT07011732

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest site: Boston Center for Memory (Newton, MA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

    NCT07033494

    • Phase 2
    • Ages 50 to 85 years
    • Sex: All

    Nearest site: Boston Center for Memory ( Site 1008) (Newton, MA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

    NCT07602582

    • Phase 3
    • Ages 55 years and older
    • Sex: All

    Nearest site: Boston Center for Memory (Newton, MA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease

    NCT07688213

    • Phase 2
    • Ages 55 to 85 years
    • Sex: All

    Nearest site: Boston Center for Memory - Newton- Site Number : 8400007 (Newton, MA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. [18F]PI-2620 Phase 3 Histopathological Study

    NCT05641688

    • Phase 3
    • Ages 50 years and older
    • Sex: All

    Nearest site: Alzheimer's Disease Center (Braintree, MA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

    NCT07589595

    • Phase 2
    • Ages 55 to 85 years
    • Sex: All

    Nearest sites: K2 Medical Research - Foxborough (Foxborough, MA); Neurology Center of New England (Foxborough, MA)

    Distance to nearest recruiting site
    ~22 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  44. Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

    NCT06808984

    • Phase 2
    • Ages 55 to 90 years
    • Sex: All

    Nearest site: K2 Medical Research (Foxborough, MA)

    Distance to nearest recruiting site
    ~22 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

    NCT07094516

    • Phase 2
    • Ages 50 to 85 years
    • Sex: All

    Nearest site: ActivMed Practices and Research (Methuen, MA)

    Distance to nearest recruiting site
    ~26 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

    NCT06584357

    • Observational
    • Ages 60 to 90 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: K2 Medical Research (East Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

    NCT05552157

    • Phase 2/3
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Butler Hospital (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

    NCT06647498

    • Phase 2/3
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Butler Hospital (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. Alzheimer's Tau Platform: Master Protocol

    NCT06957418

    • Phase 2
    • Ages 50 to 80 years
    • Sex: All

    Nearest site: Butler Hospital Memory and Aging Program (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining an Alzheimer's Disease clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.